SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6EX'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KUH_A_HLTA150_1 (CALMODULIN)	5ixx	ALR2278 PROTEIN (Nostoc sp. PCC 7120)	4 / 6	LEU A 141 MET A 144 LEU A 148 MET A 1	HEM A 201 ( 4.7A) 6EX A 202 ( 3.6A) HEM A 201 ( 3.4A) 6EX A 202 (-4.2A)	1.08A	2kuhA-5ixxA: undetectable	2kuhA-5ixxA: 15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_1 (CYTOCHROME P450 2R1)	5ixx	ALR2278 PROTEIN (Nostoc sp. PCC 7120)	5 / 12	VAL A 5 ALA A 8 VAL A 108 VAL A 52 THR A 48	6EX A 202 (-4.0A) None HEM A 201 ( 4.7A) None None	1.13A	3czhA-5ixxA: undetectable	3czhA-5ixxA: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DL9_A_V2HA602_0 (CYTOCHROME P450 2R1)	5ixx	ALR2278 PROTEIN (Nostoc sp. PCC 7120)	5 / 12	VAL A 5 ALA A 8 VAL A 108 VAL A 52 THR A 48	6EX A 202 (-4.0A) None HEM A 201 ( 4.7A) None None	1.13A	3dl9A-5ixxA: undetectable	3dl9A-5ixxA: 17.65