SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6DK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 11 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.47A 1c3sA-5g10A:
41.4		 1c3sA-5g10A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C3S_A_SHHA952_1
(HDLP (HISTONE
DEACETYLASE-LIKE
PROTEIN))		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 PRO A 210
PHE A 209
ASP A 269
PHE A 153
ASP A 181
 None
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
 1.30A 1c3sA-5g10A:
41.4		 1c3sA-5g10A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T69_A_SHHA379_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 ASP A 101
HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
TYR A 313
 6DK  A1375 (-3.0A)
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 0.63A 1t69A-5g10A:
42.0		 1t69A-5g10A:
24.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		7 / 11 HIS A 143
HIS A 144
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
 1.23A 1zz1A-5g10A:
56.8		 1zz1A-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 11 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.27A 1zz1A-5g10A:
56.8		 1zz1A-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 11 LEU A  23
ASP A 181
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 None
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.19A 1zz1A-5g10A:
56.8		 1zz1A-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  23
HIS A 144
HIS A 183
ASP A 269
TYR A 313
 None
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 1.09A 1zz1A-5g10A:
56.8		 1zz1A-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.20A 1zz1B-5g10A:
57.6
1zz1C-5g10A:
57.1		 1zz1B-5g10A:
45.23
1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 12 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.20A 1zz1B-5g10A:
57.6
1zz1C-5g10A:
57.1		 1zz1B-5g10A:
45.23
1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.05A 1zz1B-5g10A:
57.6
1zz1C-5g10A:
57.1		 1zz1B-5g10A:
45.23
1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 LEU A  23
ASP A 181
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 None
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.15A 1zz1B-5g10A:
57.6
1zz1C-5g10A:
57.1		 1zz1B-5g10A:
45.23
1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  23
HIS A 144
HIS A 183
ASP A 269
TYR A 313
 None
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 1.06A 1zz1B-5g10A:
57.6
1zz1C-5g10A:
57.1		 1zz1B-5g10A:
45.23
1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		7 / 12 HIS A 143
HIS A 144
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
 1.24A 1zz1C-5g10A:
57.1		 1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 12 HIS A 143
HIS A 144
GLY A 152
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.26A 1zz1C-5g10A:
57.1		 1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 LEU A  23
ASP A 181
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 None
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.20A 1zz1C-5g10A:
57.1		 1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 LEU A  23
HIS A 144
HIS A 183
ASP A 269
TYR A 313
 None
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 1.10A 1zz1C-5g10A:
57.1		 1zz1C-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZZ1_D_SHHD2752_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		8 / 9 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 0.25A 1zz1D-5g10A:
56.8		 1zz1D-5g10A:
45.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 5 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
 0.25A 3c0zA-5g10A:
46.6		 3c0zA-5g10A:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 8 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.33A 3c0zB-5g10A:
46.8		 3c0zB-5g10A:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		8 / 8 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
 0.36A 3c0zB-5g10A:
46.8		 3c0zB-5g10A:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 209
ASP A 269
PHE A 153
ASP A 181
 6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
 0.90A 3c0zB-5g10A:
46.8		 3c0zB-5g10A:
31.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3C0Z_C_SHHC301_1
(HISTONE DEACETYLASE
7A)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 6 ASP A 101
HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
 6DK  A1375 (-3.0A)
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
 0.69A 3c0zC-5g10A:
47.0		 3c0zC-5g10A:
31.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		8 / 10 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
PRO A 275
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.58A 4bz6A-5g10A:
40.2		 4bz6A-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 10 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.25A 4bz6A-5g10A:
40.2		 4bz6A-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_A_SHHA700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 10 LYS A  46
HIS A 143
ASP A 181
ASP A 269
GLY A 311
 None
6DK  A1375 (-4.1A)
ZN  A1372 (-2.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
 1.39A 4bz6A-5g10A:
40.2		 4bz6A-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 12 HIS A 143
HIS A 144
ASP A 181
HIS A 183
PHE A 209
ASP A 269
PRO A 275
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.65A 4bz6A-5g10A:
40.2
4bz6B-5g10A:
40.3		 4bz6A-5g10A:
24.05
4bz6B-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_B_SHHB700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.25A 4bz6A-5g10A:
40.2
4bz6B-5g10A:
40.3		 4bz6A-5g10A:
24.05
4bz6B-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
ASP A 181
HIS A 183
PHE A 209
ASP A 269
PRO A 275
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.65A 4bz6C-5g10A:
40.3		 4bz6C-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_C_SHHC700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.24A 4bz6C-5g10A:
40.3		 4bz6C-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		8 / 10 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
PRO A 275
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.59A 4bz6D-5g10A:
40.6		 4bz6D-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 10 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.24A 4bz6D-5g10A:
40.6		 4bz6D-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BZ6_D_SHHD700_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 10 HIS A 143
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.25A 4bz6D-5g10A:
40.6		 4bz6D-5g10A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		11 / 12 HIS A  39
ASP A 101
HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 None
6DK  A1375 (-3.0A)
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.58A 4lxzA-5g10A:
44.6		 4lxzA-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A  39
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 None
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.19A 4lxzA-5g10A:
44.6		 4lxzA-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.35A 4lxzA-5g10A:
44.6		 4lxzA-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.04A 4lxzA-5g10A:
44.6		 4lxzA-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 PRO A 140
HIS A 183
GLY A 152
ASP A 269
GLY A 311
 None
ZN  A1372 (-3.2A)
6DK  A1375 (-3.9A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
 1.21A 4lxzA-5g10A:
44.6		 4lxzA-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 11 HIS A  39
ASP A 101
HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 None
6DK  A1375 (-3.0A)
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.58A 4lxzB-5g10A:
44.5		 4lxzB-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A  39
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 None
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.18A 4lxzB-5g10A:
44.5		 4lxzB-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.29A 4lxzB-5g10A:
44.5		 4lxzB-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_B_SHHB408_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 143
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.07A 4lxzB-5g10A:
44.5		 4lxzB-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		11 / 12 ASP A 101
HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-3.0A)
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.55A 4lxzC-5g10A:
44.7		 4lxzC-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 PRO A 140
HIS A 183
GLY A 152
ASP A 269
GLY A 311
 None
ZN  A1372 (-3.2A)
6DK  A1375 (-3.9A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
 1.19A 4lxzC-5g10A:
44.7		 4lxzC-5g10A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.48A 4qa0A-5g10A:
42.4		 4qa0A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.27A 4qa0A-5g10A:
42.4		 4qa0A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.24A 4qa0A-5g10A:
42.4		 4qa0A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 144
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.01A 4qa0A-5g10A:
42.4		 4qa0A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 183
PHE A 209
ASP A 269
GLY A 312
TYR A 313
 ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.30A 4qa0A-5g10A:
42.4		 4qa0A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.27A 4qa0B-5g10A:
42.1		 4qa0B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 11 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.52A 4qa0B-5g10A:
42.1		 4qa0B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 143
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.25A 4qa0B-5g10A:
42.1		 4qa0B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 144
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.02A 4qa0B-5g10A:
42.1		 4qa0B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 11 HIS A 183
PHE A 209
ASP A 269
GLY A 312
TYR A 313
 ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.30A 4qa0B-5g10A:
42.1		 4qa0B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.45A 4qa2A-5g10A:
42.5		 4qa2A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.25A 4qa2A-5g10A:
42.5		 4qa2A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.25A 4qa2A-5g10A:
42.5		 4qa2A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 144
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.03A 4qa2A-5g10A:
42.5		 4qa2A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 183
PHE A 209
ASP A 269
GLY A 312
TYR A 313
 ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.29A 4qa2A-5g10A:
42.5		 4qa2A-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.44A 4qa2B-5g10A:
42.8		 4qa2B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 144
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.24A 4qa2B-5g10A:
42.8		 4qa2B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 312
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.25A 4qa2B-5g10A:
42.8		 4qa2B-5g10A:
24.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 144
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-3.9A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.03A 4qa2B-5g10A:
42.8		 4qa2B-5g10A:
24.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_A_SHHA2004_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.36A 5eeiA-5g10A:
48.6		 5eeiA-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEI_B_SHHB801_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A 143
HIS A 144
GLY A 152
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.34A 5eeiB-5g10A:
48.8		 5eeiB-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A  39
HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
GLY A 311
TYR A 313
 None
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 0.37A 5eenA-5g10A:
48.8		 5eenA-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 HIS A  39
HIS A 183
PHE A 209
ASP A 269
GLY A 312
TYR A 313
 None
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 1.31A 5eenA-5g10A:
48.8		 5eenA-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		6 / 12 HIS A 143
HIS A 144
ASP A 181
HIS A 183
ASP A 269
GLY A 267
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
 1.25A 5eenA-5g10A:
48.8		 5eenA-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_A_5OGA804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
GLY A 311
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-3.3A)
6DK  A1375 (-4.4A)
 1.06A 5eenA-5g10A:
48.8		 5eenA-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		10 / 12 HIS A  39
HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
LEU A 276
TYR A 313
 None
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.43A 5eenB-5g10A:
48.8		 5eenB-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EEN_B_5OGB804_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.96A 5eenB-5g10A:
48.8		 5eenB-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 12 HIS A  39
HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
TYR A 313
 None
6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 (-4.4A)
 0.34A 5ef8A-5g10A:
48.8		 5ef8A-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_A_LBHA2004_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 PRO A 210
PHE A 209
ASP A 269
PHE A 153
ASP A 181
 None
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
 1.39A 5ef8A-5g10A:
48.8		 5ef8A-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		9 / 12 HIS A 143
HIS A 144
PHE A 153
ASP A 181
HIS A 183
PHE A 209
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
6DK  A1375 (-3.9A)
6DK  A1375 ( 4.0A)
ZN  A1372 (-2.0A)
ZN  A1372 (-3.2A)
6DK  A1375 ( 4.0A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.41A 5ef8B-5g10A:
48.9		 5ef8B-5g10A:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5EF8_B_LBHB2004_1
(HDAC6 PROTEIN)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		5 / 12 HIS A 143
HIS A 183
ASP A 269
LEU A 276
TYR A 313
 6DK  A1375 (-4.1A)
ZN  A1372 (-3.2A)
ZN  A1372 ( 2.5A)
None
6DK  A1375 (-4.4A)
 0.94A 5ef8B-5g10A:
48.9		 5ef8B-5g10A:
30.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5g10 HDAH
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 313
TYR A 135
SER A 266
 6DK  A1375 (-4.4A)
None
None
 0.84A 5iktB-5g10A:
undetectable		 5iktB-5g10A:
19.33