SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6DB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_1 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	5 / 12	THR A 168 PHE A 108 ARG A 102 ILE A 80 LEU A 51	6DB A 304 ( 4.1A) None 6DB A 304 (-2.8A) None None	1.21A	2nyrA-5itoA: undetectable	2nyrA-5itoA: 18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_C_W9TC1005_1 (HEMOLYTIC LECTIN CEL-III)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	3 / 3	ASP A 55 GLY A 240 TYR A 42	None None 6DB A 304 (-4.7A)	0.75A	3w9tC-5itoA: undetectable	3w9tC-5itoA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_G_W9TG503_1 (HEMOLYTIC LECTIN CEL-III)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	3 / 3	ASP A 55 GLY A 240 TYR A 42	None None 6DB A 304 (-4.7A)	0.74A	3w9tG-5itoA: undetectable	3w9tG-5itoA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VM8_B_SAMB301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	5 / 10	VAL A 239 GLY A 240 GLY A 242 ILE A 80 ALA A 95	None None None None 6DB A 304 (-3.9A)	1.06A	5vm8B-5itoA: undetectable	5vm8B-5itoA: 22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB5_A_NMYA301_0 (AAC(3)-IIIB PROTEIN)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	5 / 11	TYR A 39 ASP A 187 THR A 188 THR A 168 GLY A 167	6DB A 304 (-3.9A) None None 6DB A 304 ( 4.1A) 1PE A 303 (-3.9A)	1.32A	6mb5A-5itoA: undetectable	6mb5A-5itoA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_C_NMYC302_0 (AAC(3)-IIIB PROTEIN)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	5 / 10	TYR A 39 ASP A 187 THR A 188 THR A 168 GLY A 167	6DB A 304 (-3.9A) None None 6DB A 304 ( 4.1A) 1PE A 303 (-3.9A)	1.34A	6mb9C-5itoA: undetectable	6mb9C-5itoA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MB9_D_NMYD302_0 (AAC(3)-IIIB PROTEIN)	5ito	NOPALINE-BINDING PERIPLASMIC PROTEIN (Agrobacterium fabrum)	5 / 10	TYR A 39 ASP A 187 THR A 188 THR A 168 GLY A 167	6DB A 304 (-3.9A) None None 6DB A 304 ( 4.1A) 1PE A 303 (-3.9A)	1.35A	6mb9D-5itoA: undetectable	6mb9D-5itoA: 18.67

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NYR_B_SVRB401_1","NAD-DEPENDENT DEACETYLASE SIRTUIN-5;NAD-DEPENDENT DEACETYLASE SIRTUIN-5","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",5,"THR A 168;PHE A 108;ARG A 102;ILE A  80;LEU A  51","6DB A 304 ( 4.1A);None;6DB A 304 (-2.8A);None;None","1.21A","2nyrA-5itoA:undetectable",null],["3W9T_C_W9TC1005_1","HEMOLYTIC LECTIN CEL-III","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",3,"ASP A  55;GLY A 240;TYR A  42","None;None;6DB A 304 (-4.7A)","0.75A","3w9tC-5itoA:undetectable","2nyrA-5itoA:18.47"],["3W9T_G_W9TG503_1","HEMOLYTIC LECTIN CEL-III","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",3,"ASP A  55;GLY A 240;TYR A  42","None;None;6DB A 304 (-4.7A)","0.74A","3w9tG-5itoA:undetectable","3w9tC-5itoA:19.28"],["5VM8_B_SAMB301_0","RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",5,"VAL A 239;GLY A 240;GLY A 242;ILE A  80;ALA A  95","None;None;None;None;6DB A 304 (-3.9A)","1.06A","5vm8B-5itoA:undetectable","3w9tG-5itoA:19.28"],["6MB5_A_NMYA301_0","AAC(3)-IIIB PROTEIN","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",5,"TYR A  39;ASP A 187;THR A 188;THR A 168;GLY A 167","6DB A 304 (-3.9A);None;None;6DB A 304 ( 4.1A);1PE A 303 (-3.9A)","1.32A","6mb5A-5itoA:undetectable","5vm8B-5itoA:22.46"],["6MB9_C_NMYC302_0","AAC(3)-IIIB PROTEIN","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",5,"TYR A  39;ASP A 187;THR A 188;THR A 168;GLY A 167","6DB A 304 (-3.9A);None;None;6DB A 304 ( 4.1A);1PE A 303 (-3.9A)","1.34A","6mb9C-5itoA:undetectable","6mb5A-5itoA:18.67"],["6MB9_D_NMYD302_0","AAC(3)-IIIB PROTEIN","5ito","NOPALINE-BINDING PERIPLASMIC PROTEIN","Agrobacterium fabrum",5,"TYR A  39;ASP A 187;THR A 188;THR A 168;GLY A 167","6DB A 304 (-3.9A);None;None;6DB A 304 ( 4.1A);1PE A 303 (-3.9A)","1.35A","6mb9D-5itoA:undetectable","6mb9C-5itoA:18.67"]]