SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6A9'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 440
PHE A 402
GLU A 484
GLY A 444
 None
None
6A9  A 903 ( 3.9A)
None
 1.13A 1icuA-5mhfA:
undetectable
1icuB-5mhfA:
undetectable		 1icuA-5mhfA:
16.43
1icuB-5mhfA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 402
GLU A 484
GLY A 444
PHE A 440
 None
6A9  A 903 ( 3.9A)
None
None
 1.16A 1icuA-5mhfA:
undetectable
1icuB-5mhfA:
undetectable		 1icuA-5mhfA:
16.43
1icuB-5mhfA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 PHE A 440
PHE A 402
GLU A 484
GLY A 444
 None
None
6A9  A 903 ( 3.9A)
None
 1.17A 1kqbA-5mhfA:
undetectable
1kqbB-5mhfA:
undetectable		 1kqbA-5mhfA:
undetectable
1kqbB-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 6 GLU A 804
TYR A 746
PHE A 819
PRO A 436
 6A9  A 903 ( 4.9A)
6A9  A 903 (-3.9A)
6A9  A 903 ( 4.9A)
6A9  A 903 (-4.3A)
 1.45A 2vmyA-5mhfA:
undetectable		 2vmyA-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		3 / 3 ASN A 508
ASP A 448
ARG A 748
 None
6A9  A 903 (-3.0A)
None
 0.77A 3k13C-5mhfA:
undetectable		 3k13C-5mhfA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5mhf MANNOSYL-OLIGOSACCHA
RIDE GLUCOSIDASE
(Mus
musculus) 		4 / 7 GLN A 502
GLU A 449
GLU A 484
PRO A 436
 None
None
6A9  A 903 ( 3.9A)
6A9  A 903 (-4.3A)
 1.42A 3ql6A-5mhfA:
undetectable		 3ql6A-5mhfA:
8.60