SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '63F'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CEA_B_ACAB90_1 (PLASMINOGEN)	3qgh	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 7	ARG A 158 ASP A 318 ASP A 319 TYR A 448	None None None 63F A 601 (-4.1A)	1.40A	1ceaB-3qghA: undetectable	1ceaB-3qghA: 10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2G70_A_SAMA2001_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	3qgh	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 7	TYR A 191 GLY A 317 THR A 292 ASP A 318	63F A 601 (-4.9A) None 63F A 601 ( 4.7A) None	1.07A	2g70A-3qghA: undetectable	2g70A-3qghA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J24_B_ESTB600_1 (ESTROGEN RECEPTOR BETA)	3qgh	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	5 / 12	LEU A 409 LEU A 425 MET A 426 ILE A 462 ILE A 463	None None None 63F A 601 (-4.0A) None	0.99A	4j24B-3qghA: undetectable	4j24B-3qghA: 16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IK1_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	3qgh	RNA-DIRECTED RNA POLYMERASE (Hepacivirus C)	4 / 5	PHE A 551 GLY A 543 ASP A 458 ILE A 462	63F A 601 (-4.3A) None None 63F A 601 (-4.0A)	0.78A	5ik1A-3qghA: undetectable	5ik1A-3qghA: 21.54

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CEA_B_ACAB90_1","PLASMINOGEN","3qgh","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"ARG A 158;ASP A 318;ASP A 319;TYR A 448","None;None;None;63F A 601 (-4.1A)","1.40A","1ceaB-3qghA:undetectable",null],["2G70_A_SAMA2001_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","3qgh","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"TYR A 191;GLY A 317;THR A 292;ASP A 318","63F A 601 (-4.9A);None;63F A 601 ( 4.7A);None","1.07A","2g70A-3qghA:undetectable","1ceaB-3qghA:10.90"],["4J24_B_ESTB600_1","ESTROGEN RECEPTOR BETA","3qgh","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",5,"LEU A 409;LEU A 425;MET A 426;ILE A 462;ILE A 463","None;None;None;63F A 601 (-4.0A);None","0.99A","4j24B-3qghA:undetectable","2g70A-3qghA:20.81"],["5IK1_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","3qgh","RNA-DIRECTED RNA POLYMERASE","Hepacivirus C",4,"PHE A 551;GLY A 543;ASP A 458;ILE A 462","63F A 601 (-4.3A);None;None;63F A 601 (-4.0A)","0.78A","5ik1A-3qghA:undetectable","4j24B-3qghA:16.26"]]