SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '61G'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		5 / 11 ALA A 119
LEU A 120
LEU A 135
HIS A  93
SER A 128
 61G  A 403 (-4.8A)
None
61G  A 403 ( 4.5A)
PIS  A 402 (-4.1A)
None
 1.01A 1h9zA-5hc8A:
undetectable		 1h9zA-5hc8A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		5 / 11 ALA A 119
LEU A 120
LEU A 135
HIS A  93
SER A 128
 61G  A 403 (-4.8A)
None
61G  A 403 ( 4.5A)
PIS  A 402 (-4.1A)
None
 1.07A 1ha2A-5hc8A:
undetectable		 1ha2A-5hc8A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		4 / 7 LEU A 135
TYR A 139
ILE A  75
GLY A  92
 61G  A 403 ( 4.5A)
None
None
None
 0.91A 4eq4A-5hc8A:
undetectable		 4eq4A-5hc8A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		4 / 7 LEU A 135
TYR A 139
ILE A  75
GLY A  92
 61G  A 403 ( 4.5A)
None
None
None
 0.91A 4eqlA-5hc8A:
undetectable		 4eqlA-5hc8A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_B_SALB602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		4 / 7 LEU A 135
TYR A 139
ILE A  75
GLY A  92
 61G  A 403 ( 4.5A)
None
None
None
 0.90A 4eqlB-5hc8A:
undetectable		 4eqlB-5hc8A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		4 / 6 LEU A 135
TYR A 139
ILE A  75
GLY A  92
 61G  A 403 ( 4.5A)
None
None
None
 0.94A 4l39A-5hc8A:
undetectable		 4l39A-5hc8A:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5hc8 PRENYLTRANSFERENCE
FOR PROTEIN
(Lavandula
lanata) 		4 / 7 LEU A 135
TYR A 139
ILE A  75
GLY A  92
 61G  A 403 ( 4.5A)
None
None
None
 0.92A 4l39B-5hc8A:
undetectable		 4l39B-5hc8A:
18.26