SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5XJ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	8 / 12	ALA A 481 LEU A 514 THR A 529 TRP A 531 CYH A 532 LEU A 567 HIS A 574 GLY A 593	5XJ A 801 (-3.1A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None None 5XJ A 801 ( 3.7A)	0.54A	1uwhA-5fd2A: 36.5	1uwhA-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWH_A_BAXA1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	8 / 12	ALA A 481 LEU A 514 THR A 529 TRP A 531 LEU A 567 HIS A 574 GLY A 593 PHE A 583	5XJ A 801 (-3.1A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) None None 5XJ A 801 ( 3.7A) 5XJ A 801 (-4.3A)	1.16A	1uwhA-5fd2A: 36.5	1uwhA-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWH_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 CYH A 532 LEU A 567 HIS A 574 GLY A 593	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None None 5XJ A 801 ( 3.7A)	0.54A	1uwhB-5fd2A: 36.4	1uwhB-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWJ_A_BAXA1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	VAL A 471 ALA A 481 THR A 508 LEU A 514 THR A 529 TRP A 531 CYH A 532 LEU A 567 HIS A 574 GLY A 593	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) None 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None None 5XJ A 801 ( 3.7A)	0.55A	1uwjA-5fd2A: 35.4	1uwjA-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWJ_A_BAXA1723_2 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 7	ILE A 463 LYS A 483 ILE A 513 ILE A 572	5XJ A 801 ( 4.7A) 5XJ A 801 (-3.8A) None None	0.59A	1uwjA-5fd2A: 35.4	1uwjA-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWJ_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	ILE A 463 VAL A 471 ALA A 481 LEU A 514 THR A 529 TRP A 531 CYH A 532 GLY A 593 LYS A 601	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 ( 3.7A) None	0.98A	1uwjB-5fd2A: 35.3	1uwjB-5fd2A: 99.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1UWJ_B_BAXB1723_1 (B-RAF PROTO-ONCOGENE SERINE/THREONINE-PRO TEIN KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	ILE A 463 VAL A 471 ALA A 481 LEU A 514 THR A 529 TRP A 531 CYH A 532 LEU A 567 HIS A 574 GLY A 593	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None None 5XJ A 801 ( 3.7A)	0.58A	1uwjB-5fd2A: 35.3	1uwjB-5fd2A: 99.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_A_2FAA500_2 (ADENOSYLHOMOCYSTEINA SE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 5	GLN A 530 THR A 529 HIS A 574 LEU A 567	None 5XJ A 801 (-3.4A) None None	1.31A	2zj0A-5fd2A: undetectable	2zj0A-5fd2A: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_A_ADNA500_2 (ADENOSYLHOMOCYSTEINA SE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 5	GLN A 530 THR A 529 HIS A 574 LEU A 567	None 5XJ A 801 (-3.4A) None None	1.37A	3ce6A-5fd2A: undetectable	3ce6A-5fd2A: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CE6_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 5	GLN A 530 THR A 529 HIS A 574 LEU A 567	None 5XJ A 801 (-3.4A) None None	1.36A	3ce6C-5fd2A: undetectable	3ce6C-5fd2A: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_A_TOPA208_1 (DIHYDROFOLATE REDUCTASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	5 / 11	ALA A 598 GLU A 501 LEU A 505 VAL A 504 ILE A 513	None None 5XJ A 801 (-3.8A) None None	1.12A	3jw5A-5fd2A: undetectable	3jw5A-5fd2A: 21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JW5_B_TOPB208_1 (DIHYDROFOLATE REDUCTASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	5 / 10	ALA A 598 GLU A 501 LEU A 505 VAL A 504 ILE A 513	None None 5XJ A 801 (-3.8A) None None	1.14A	3jw5B-5fd2A: undetectable	3jw5B-5fd2A: 21.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3OG7_A_032A1_1 (AKAP9-BRAF FUSION PROTEIN)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	12 / 12	ILE A 463 VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 THR A 529 TRP A 531 CYH A 532 PHE A 583 PHE A 595 GLY A 596	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.57A	3og7A-5fd2A: 37.3	3og7A-5fd2A: 90.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B1000_1 (P38A)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	5 / 12	GLY A 464 VAL A 471 ALA A 481 LYS A 483 THR A 529	None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.4A)	0.50A	3ohtB-5fd2A: 17.1	3ohtB-5fd2A: 26.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	5 / 8	ILE A 463 VAL A 471 ALA A 481 ASN A 581 ASP A 594	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) None None	0.52A	4ogrA-5fd2A: 23.9	4ogrA-5fd2A: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	6 / 9	ILE A 463 VAL A 471 ALA A 481 CYH A 532 ASN A 581 ASP A 594	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-4.6A) None None	0.67A	4ogrI-5fd2A: 17.0	4ogrI-5fd2A: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R7I_A_STIA1001_1 (MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	6 / 12	VAL A 471 ALA A 481 LYS A 483 THR A 529 CYH A 532 GLY A 593	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.6A) 5XJ A 801 ( 3.7A)	0.59A	4r7iA-5fd2A: 14.2	4r7iA-5fd2A: 28.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_A_032A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	ALA A 481 LYS A 483 LEU A 514 ILE A 527 THR A 529 SER A 536 PHE A 583 GLY A 593 PHE A 595 GLY A 596	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) None 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.66A	4rzvA-5fd2A: 14.0	4rzvA-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_A_032A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	ALA A 481 LYS A 483 LEU A 514 ILE A 527 THR A 529 TRP A 531 PHE A 583 GLY A 593 PHE A 595 GLY A 596	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.53A	4rzvA-5fd2A: 14.0	4rzvA-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_A_032A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	LYS A 483 LEU A 514 ILE A 527 THR A 529 SER A 535 SER A 536 PHE A 583 GLY A 593 PHE A 595 GLY A 596	5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) None None 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.71A	4rzvA-5fd2A: 14.0	4rzvA-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_A_032A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 5	ILE A 463 VAL A 471 PHE A 516 CYH A 532	5XJ A 801 ( 4.7A) 5XJ A 801 (-4.6A) None 5XJ A 801 (-4.6A)	0.54A	4rzvA-5fd2A: 14.0	4rzvA-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_A_032A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 5	VAL A 471 PHE A 516 CYH A 532 HIS A 539	5XJ A 801 (-4.6A) None 5XJ A 801 (-4.6A) None	0.98A	4rzvA-5fd2A: 14.0	4rzvA-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4RZV_B_032B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	12 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 CYH A 532 SER A 536 PHE A 583 GLY A 593 PHE A 595 GLY A 596	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.82A	4rzvB-5fd2A: 36.5	4rzvB-5fd2A: 93.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XV2_A_P06A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 CYH A 532 PHE A 583 GLY A 593 PHE A 595	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A)	0.70A	4xv2A-5fd2A: 30.7	4xv2A-5fd2A: 90.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XV2_A_P06A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 PHE A 583 GLY A 593 ASP A 594 PHE A 595	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) None 5XJ A 801 (-3.7A)	0.78A	4xv2A-5fd2A: 30.7	4xv2A-5fd2A: 90.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XV2_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	ALA A 481 LYS A 483 LEU A 505 LEU A 514 THR A 529 TRP A 531 CYH A 532 PHE A 583 GLY A 593 PHE A 595	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A)	0.76A	4xv2B-5fd2A: 36.1	4xv2B-5fd2A: 90.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4XV2_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	10 / 12	ALA A 481 LYS A 483 LEU A 505 LEU A 514 THR A 529 TRP A 531 PHE A 583 GLY A 593 ASP A 594 PHE A 595	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) None 5XJ A 801 (-3.7A)	0.80A	4xv2B-5fd2A: 36.1	4xv2B-5fd2A: 90.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BOJ_B_4TXB201_1 (TRANSTHYRETIN)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 7	LYS A 483 LEU A 485 THR A 529 LEU A 525	5XJ A 801 (-3.8A) None 5XJ A 801 (-3.4A) None	0.86A	5bojB-5fd2A: undetectable	5bojB-5fd2A: 22.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CSW_A_P06A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	11 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 THR A 529 TRP A 531 CYH A 532 PHE A 583 GLY A 593 PHE A 595	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A)	0.74A	5cswA-5fd2A: 37.1	5cswA-5fd2A: 93.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CSW_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	7 / 12	PHE A 468 ALA A 481 LYS A 483 LEU A 514 THR A 529 CYH A 532 GLY A 593	None 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.6A) 5XJ A 801 ( 3.7A)	1.50A	5cswB-5fd2A: 36.2	5cswB-5fd2A: 93.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CSW_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	11 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 THR A 529 TRP A 531 CYH A 532 PHE A 583 GLY A 593 PHE A 595	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) 5XJ A 801 (-3.7A)	0.72A	5cswB-5fd2A: 36.2	5cswB-5fd2A: 93.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HES_A_032A401_1 (MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	6 / 12	VAL A 471 ALA A 481 ILE A 527 THR A 529 PHE A 595 GLY A 596	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.37A	5hesA-5fd2A: 10.2	5hesA-5fd2A: 31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HES_A_032A401_2 (MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 6	LYS A 483 PHE A 516 SER A 536 ASP A 594	5XJ A 801 (-3.8A) None None None	0.59A	5hesA-5fd2A: 10.2	5hesA-5fd2A: 31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HES_B_032B401_1 (MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	7 / 12	VAL A 471 ALA A 481 LYS A 483 ILE A 527 THR A 529 PHE A 595 GLY A 596	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-3.7A) 5XJ A 801 (-3.7A)	0.32A	5hesB-5fd2A: 21.7	5hesB-5fd2A: 31.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HI2_A_BAXA801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 CYH A 532 LEU A 567 HIS A 574 GLY A 593	5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.6A) None None 5XJ A 801 ( 3.7A)	0.59A	5hi2A-5fd2A: 25.2	5hi2A-5fd2A: 89.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_A_P06A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 505 LEU A 514 ILE A 527 THR A 529 TRP A 531 PHE A 583	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A)	0.64A	5hieA-5fd2A: 35.2	5hieA-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_A_P06A801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 ILE A 527 THR A 529 TRP A 531 PHE A 583 GLY A 593	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A)	0.56A	5hieA-5fd2A: 35.2	5hieA-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 7	ILE A 463 GLY A 464 CYH A 532 PHE A 595	5XJ A 801 ( 4.7A) None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.7A)	0.75A	5hieA-5fd2A: 35.6	5hieA-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 7	ILE A 463 GLY A 464 PHE A 516 CYH A 532	5XJ A 801 ( 4.7A) None None 5XJ A 801 (-4.6A)	0.46A	5hieA-5fd2A: 35.6	5hieA-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_B_P06B801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 ILE A 527 THR A 529 TRP A 531 PHE A 583 GLY A 593	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A)	0.56A	5hieB-5fd2A: 35.7	5hieB-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_C_P06C801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	GLY A 464 VAL A 471 ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 PHE A 583 GLY A 593	None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A)	0.51A	5hieC-5fd2A: 35.1	5hieC-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_C_P06C801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 THR A 529 TRP A 531 PHE A 583 GLY A 593 ASP A 594	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A) None	0.70A	5hieC-5fd2A: 35.1	5hieC-5fd2A: 97.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5HIE_D_P06D801_1 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	9 / 12	VAL A 471 ALA A 481 LYS A 483 LEU A 514 ILE A 527 THR A 529 TRP A 531 PHE A 583 GLY A 593	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-4.5A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.4A) 5XJ A 801 (-4.3A) 5XJ A 801 ( 3.7A)	0.56A	5hieD-5fd2A: 35.1	5hieD-5fd2A: 97.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IZJ_G_AZ1G2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAR-DAR)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 7	GLY A 464 GLY A 466 VAL A 471 LYS A 483	None None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.8A)	0.27A	5izjA-5fd2A: 7.3	5izjA-5fd2A: 25.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_B_AG2B501_1 (ARGININE/AGMATINE ANTIPORTER)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 6	ILE A 573 GLY A 593 ASN A 581 ILE A 572	None 5XJ A 801 ( 3.7A) None None	1.00A	5j4nB-5fd2A: undetectable	5j4nB-5fd2A: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J5X_B_AZ1B2_1 (CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA 47P-AZ1-DAL-DAR-DAR- DAR-DAR)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	5 / 7	GLY A 464 GLY A 466 VAL A 471 LYS A 483 ASP A 594	None None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.8A) None	0.52A	5j5xA-5fd2A: 16.0	5j5xA-5fd2A: 25.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5P9I_A_1E8A701_1 (TYROSINE-PROTEIN KINASE BTK)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	7 / 12	GLY A 469 VAL A 471 ALA A 481 LYS A 483 ILE A 527 THR A 529 PHE A 595	None 5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 ( 4.0A) 5XJ A 801 (-3.4A) 5XJ A 801 (-3.7A)	1.40A	5p9iA-5fd2A: 22.6	5p9iA-5fd2A: 30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_1 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	6 / 12	VAL A 471 ALA A 481 LYS A 483 THR A 529 CYH A 532 PHE A 583	5XJ A 801 (-4.6A) 5XJ A 801 (-3.1A) 5XJ A 801 (-3.8A) 5XJ A 801 (-3.4A) 5XJ A 801 (-4.6A) 5XJ A 801 (-4.3A)	0.65A	5vcyA-5fd2A: 23.1	5vcyA-5fd2A: 26.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F3N_B_ADNB505_2 (-)	5fd2	SERINE/THREONINE-PRO TEIN KINASE B-RAF (Homo sapiens)	4 / 4	GLN A 530 THR A 529 HIS A 574 LEU A 567	None 5XJ A 801 (-3.4A) None None	1.50A	6f3nB-5fd2A: undetectable	6f3nB-5fd2A: 22.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UWH_A_BAXA1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",8,"ALA A 481;LEU A 514;THR A 529;TRP A 531;CYH A 532;LEU A 567;HIS A 574;GLY A 593","5XJ A 801 (-3.1A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;None;5XJ A 801 ( 3.7A)","0.54A","1uwhA-5fd2A:36.5",null],["1UWH_A_BAXA1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",8,"ALA A 481;LEU A 514;THR A 529;TRP A 531;LEU A 567;HIS A 574;GLY A 593;PHE A 583","5XJ A 801 (-3.1A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);None;None;5XJ A 801 ( 3.7A);5XJ A 801 (-4.3A)","1.16A","1uwhA-5fd2A:36.5","1uwhA-5fd2A:99.64"],["1UWH_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;CYH A 532;LEU A 567;HIS A 574;GLY A 593","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;None;5XJ A 801 ( 3.7A)","0.54A","1uwhB-5fd2A:36.4","1uwhA-5fd2A:99.64"],["1UWJ_A_BAXA1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"VAL A 471;ALA A 481;THR A 508;LEU A 514;THR A 529;TRP A 531;CYH A 532;LEU A 567;HIS A 574;GLY A 593","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);None;5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;None;5XJ A 801 ( 3.7A)","0.55A","1uwjA-5fd2A:35.4","1uwhB-5fd2A:99.64"],["1UWJ_A_BAXA1723_2","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"ILE A 463;LYS A 483;ILE A 513;ILE A 572","5XJ A 801 ( 4.7A);5XJ A 801 (-3.8A);None;None","0.59A","1uwjA-5fd2A:35.4","1uwjA-5fd2A:99.64"],["1UWJ_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"ILE A 463;VAL A 471;ALA A 481;LEU A 514;THR A 529;TRP A 531;CYH A 532;GLY A 593;LYS A 601","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 ( 3.7A);None","0.98A","1uwjB-5fd2A:35.3","1uwjA-5fd2A:99.64"],["1UWJ_B_BAXB1723_1","B-RAF PROTO-ONCOGENE SERINE\/THREONINE-PROTEIN KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"ILE A 463;VAL A 471;ALA A 481;LEU A 514;THR A 529;TRP A 531;CYH A 532;LEU A 567;HIS A 574;GLY A 593","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;None;5XJ A 801 ( 3.7A)","0.58A","1uwjB-5fd2A:35.3","1uwjB-5fd2A:99.64"],["2ZJ0_A_2FAA500_2","ADENOSYLHOMOCYSTEINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"GLN A 530;THR A 529;HIS A 574;LEU A 567","None;5XJ A 801 (-3.4A);None;None","1.31A","2zj0A-5fd2A:undetectable","1uwjB-5fd2A:99.64"],["3CE6_A_ADNA500_2","ADENOSYLHOMOCYSTEINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"GLN A 530;THR A 529;HIS A 574;LEU A 567","None;5XJ A 801 (-3.4A);None;None","1.37A","3ce6A-5fd2A:undetectable","2zj0A-5fd2A:20.93"],["3CE6_C_ADNC500_2","ADENOSYLHOMOCYSTEINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"GLN A 530;THR A 529;HIS A 574;LEU A 567","None;5XJ A 801 (-3.4A);None;None","1.36A","3ce6C-5fd2A:undetectable","3ce6A-5fd2A:20.97"],["3JW5_A_TOPA208_1","DIHYDROFOLATE REDUCTASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",5,"ALA A 598;GLU A 501;LEU A 505;VAL A 504;ILE A 513","None;None;5XJ A 801 (-3.8A);None;None","1.12A","3jw5A-5fd2A:undetectable","3ce6C-5fd2A:20.97"],["3JW5_B_TOPB208_1","DIHYDROFOLATE REDUCTASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",5,"ALA A 598;GLU A 501;LEU A 505;VAL A 504;ILE A 513","None;None;5XJ A 801 (-3.8A);None;None","1.14A","3jw5B-5fd2A:undetectable","3jw5A-5fd2A:21.07"],["3OG7_A_032A1_1","AKAP9-BRAF FUSION PROTEIN","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",12,"ILE A 463;VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;THR A 529;TRP A 531;CYH A 532;PHE A 583;PHE A 595;GLY A 596","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.57A","3og7A-5fd2A:37.3","3jw5B-5fd2A:21.07"],["3OHT_B_1N1B1000_1","P38A","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",5,"GLY A 464;VAL A 471;ALA A 481;LYS A 483;THR A 529","None;5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.4A)","0.50A","3ohtB-5fd2A:17.1","3og7A-5fd2A:90.48"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",5,"ILE A 463;VAL A 471;ALA A 481;ASN A 581;ASP A 594","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);None;None","0.52A","4ogrA-5fd2A:23.9","3ohtB-5fd2A:26.09"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",6,"ILE A 463;VAL A 471;ALA A 481;CYH A 532;ASN A 581;ASP A 594","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-4.6A);None;None","0.67A","4ogrI-5fd2A:17.0","4ogrA-5fd2A:24.72"],["4R7I_A_STIA1001_1","MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",6,"VAL A 471;ALA A 481;LYS A 483;THR A 529;CYH A 532;GLY A 593","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.4A);5XJ A 801 (-4.6A);5XJ A 801 ( 3.7A)","0.59A","4r7iA-5fd2A:14.2","4ogrI-5fd2A:24.72"],["4RZV_A_032A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"ALA A 481;LYS A 483;LEU A 514;ILE A 527;THR A 529;SER A 536;PHE A 583;GLY A 593;PHE A 595;GLY A 596","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);None;5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.66A","4rzvA-5fd2A:14.0","4r7iA-5fd2A:28.65"],["4RZV_A_032A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"ALA A 481;LYS A 483;LEU A 514;ILE A 527;THR A 529;TRP A 531;PHE A 583;GLY A 593;PHE A 595;GLY A 596","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.53A","4rzvA-5fd2A:14.0","4rzvA-5fd2A:93.95"],["4RZV_A_032A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"LYS A 483;LEU A 514;ILE A 527;THR A 529;SER A 535;SER A 536;PHE A 583;GLY A 593;PHE A 595;GLY A 596","5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);None;None;5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.71A","4rzvA-5fd2A:14.0","4rzvA-5fd2A:93.95"],["4RZV_A_032A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"ILE A 463;VAL A 471;PHE A 516;CYH A 532","5XJ A 801 ( 4.7A);5XJ A 801 (-4.6A);None;5XJ A 801 (-4.6A)","0.54A","4rzvA-5fd2A:14.0","4rzvA-5fd2A:93.95"],["4RZV_A_032A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"VAL A 471;PHE A 516;CYH A 532;HIS A 539","5XJ A 801 (-4.6A);None;5XJ A 801 (-4.6A);None","0.98A","4rzvA-5fd2A:14.0","4rzvA-5fd2A:93.95"],["4RZV_B_032B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",12,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;CYH A 532;SER A 536;PHE A 583;GLY A 593;PHE A 595;GLY A 596","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.82A","4rzvB-5fd2A:36.5","4rzvA-5fd2A:93.95"],["4XV2_A_P06A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;CYH A 532;PHE A 583;GLY A 593;PHE A 595","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A)","0.70A","4xv2A-5fd2A:30.7","4rzvB-5fd2A:93.95"],["4XV2_A_P06A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;PHE A 583;GLY A 593;ASP A 594;PHE A 595","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);None;5XJ A 801 (-3.7A)","0.78A","4xv2A-5fd2A:30.7","4xv2A-5fd2A:90.24"],["4XV2_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"ALA A 481;LYS A 483;LEU A 505;LEU A 514;THR A 529;TRP A 531;CYH A 532;PHE A 583;GLY A 593;PHE A 595","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A)","0.76A","4xv2B-5fd2A:36.1","4xv2A-5fd2A:90.24"],["4XV2_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",10,"ALA A 481;LYS A 483;LEU A 505;LEU A 514;THR A 529;TRP A 531;PHE A 583;GLY A 593;ASP A 594;PHE A 595","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);None;5XJ A 801 (-3.7A)","0.80A","4xv2B-5fd2A:36.1","4xv2B-5fd2A:90.24"],["5BOJ_B_4TXB201_1","TRANSTHYRETIN","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"LYS A 483;LEU A 485;THR A 529;LEU A 525","5XJ A 801 (-3.8A);None;5XJ A 801 (-3.4A);None","0.86A","5bojB-5fd2A:undetectable","4xv2B-5fd2A:90.24"],["5CSW_A_P06A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",11,"VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;THR A 529;TRP A 531;CYH A 532;PHE A 583;GLY A 593;PHE A 595","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A)","0.74A","5cswA-5fd2A:37.1","5bojB-5fd2A:22.17"],["5CSW_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",7,"PHE A 468;ALA A 481;LYS A 483;LEU A 514;THR A 529;CYH A 532;GLY A 593","None;5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.6A);5XJ A 801 ( 3.7A)","1.50A","5cswB-5fd2A:36.2","5cswA-5fd2A:93.97"],["5CSW_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",11,"VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;THR A 529;TRP A 531;CYH A 532;PHE A 583;GLY A 593;PHE A 595","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);5XJ A 801 (-3.7A)","0.72A","5cswB-5fd2A:36.2","5cswB-5fd2A:93.97"],["5HES_A_032A401_1","MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",6,"VAL A 471;ALA A 481;ILE A 527;THR A 529;PHE A 595;GLY A 596","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.37A","5hesA-5fd2A:10.2","5cswB-5fd2A:93.97"],["5HES_A_032A401_2","MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"LYS A 483;PHE A 516;SER A 536;ASP A 594","5XJ A 801 (-3.8A);None;None;None","0.59A","5hesA-5fd2A:10.2","5hesA-5fd2A:31.12"],["5HES_B_032B401_1","MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE MLT","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",7,"VAL A 471;ALA A 481;LYS A 483;ILE A 527;THR A 529;PHE A 595;GLY A 596","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-3.7A);5XJ A 801 (-3.7A)","0.32A","5hesB-5fd2A:21.7","5hesA-5fd2A:31.12"],["5HI2_A_BAXA801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;CYH A 532;LEU A 567;HIS A 574;GLY A 593","5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.6A);None;None;5XJ A 801 ( 3.7A)","0.59A","5hi2A-5fd2A:25.2","5hesB-5fd2A:31.12"],["5HIE_A_P06A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"VAL A 471;ALA A 481;LYS A 483;LEU A 505;LEU A 514;ILE A 527;THR A 529;TRP A 531;PHE A 583","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A)","0.64A","5hieA-5fd2A:35.2","5hi2A-5fd2A:89.23"],["5HIE_A_P06A801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;ILE A 527;THR A 529;TRP A 531;PHE A 583;GLY A 593","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A)","0.56A","5hieA-5fd2A:35.2","5hieA-5fd2A:97.68"],["5HIE_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"ILE A 463;GLY A 464;CYH A 532;PHE A 595","5XJ A 801 ( 4.7A);None;5XJ A 801 (-4.6A);5XJ A 801 (-3.7A)","0.75A","5hieA-5fd2A:35.6","5hieA-5fd2A:97.68"],["5HIE_A_P06A801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"ILE A 463;GLY A 464;PHE A 516;CYH A 532","5XJ A 801 ( 4.7A);None;None;5XJ A 801 (-4.6A)","0.46A","5hieA-5fd2A:35.6","5hieA-5fd2A:97.68"],["5HIE_B_P06B801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;ILE A 527;THR A 529;TRP A 531;PHE A 583;GLY A 593","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A)","0.56A","5hieB-5fd2A:35.7","5hieA-5fd2A:97.68"],["5HIE_C_P06C801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"GLY A 464;VAL A 471;ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;PHE A 583;GLY A 593","None;5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A)","0.51A","5hieC-5fd2A:35.1","5hieB-5fd2A:97.68"],["5HIE_C_P06C801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;THR A 529;TRP A 531;PHE A 583;GLY A 593;ASP A 594","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A);None","0.70A","5hieC-5fd2A:35.1","5hieC-5fd2A:97.68"],["5HIE_D_P06D801_1","SERINE\/THREONINE-PROTEIN KINASE B-RAF","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",9,"VAL A 471;ALA A 481;LYS A 483;LEU A 514;ILE A 527;THR A 529;TRP A 531;PHE A 583;GLY A 593","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-4.5A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-4.4A);5XJ A 801 (-4.3A);5XJ A 801 ( 3.7A)","0.56A","5hieD-5fd2A:35.1","5hieC-5fd2A:97.68"],["5IZJ_G_AZ1G2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAR-DAR","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"GLY A 464;GLY A 466;VAL A 471;LYS A 483","None;None;5XJ A 801 (-4.6A);5XJ A 801 (-3.8A)","0.27A","5izjA-5fd2A:7.3","5hieD-5fd2A:97.68"],["5J4N_B_AG2B501_1","ARGININE\/AGMATINE ANTIPORTER","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"ILE A 573;GLY A 593;ASN A 581;ILE A 572","None;5XJ A 801 ( 3.7A);None;None","1.00A","5j4nB-5fd2A:undetectable","5izjA-5fd2A:25.68"],["5J5X_B_AZ1B2_1","CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA;47P-AZ1-DAL-DAR-DAR-DAR-DAR","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",5,"GLY A 464;GLY A 466;VAL A 471;LYS A 483;ASP A 594","None;None;5XJ A 801 (-4.6A);5XJ A 801 (-3.8A);None","0.52A","5j5xA-5fd2A:16.0","5j4nB-5fd2A:21.62"],["5P9I_A_1E8A701_1","TYROSINE-PROTEIN KINASE BTK","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",7,"GLY A 469;VAL A 471;ALA A 481;LYS A 483;ILE A 527;THR A 529;PHE A 595","None;5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 ( 4.0A);5XJ A 801 (-3.4A);5XJ A 801 (-3.7A)","1.40A","5p9iA-5fd2A:22.6","5j5xA-5fd2A:25.68"],["5VCY_A_DB8A401_1","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",6,"VAL A 471;ALA A 481;LYS A 483;THR A 529;CYH A 532;PHE A 583","5XJ A 801 (-4.6A);5XJ A 801 (-3.1A);5XJ A 801 (-3.8A);5XJ A 801 (-3.4A);5XJ A 801 (-4.6A);5XJ A 801 (-4.3A)","0.65A","5vcyA-5fd2A:23.1","5p9iA-5fd2A:30.70"],["6F3N_B_ADNB505_2","-","5fd2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","Homo sapiens",4,"GLN A 530;THR A 529;HIS A 574;LEU A 567","None;5XJ A 801 (-3.4A);None;None","1.50A","6f3nB-5fd2A:undetectable","5vcyA-5fd2A:26.73"]]