SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5VV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.10A 1rjdA-5fbzA:
undetectable		 1rjdA-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.10A 1rjdB-5fbzA:
2.2		 1rjdB-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A  86
GLY A  78
SER A 228
LEU A  33
LEU A  91
 None
None
5VV  A   1 ( 3.0A)
None
None
 1.08A 1rjdC-5fbzA:
2.2		 1rjdC-5fbzA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 3ln1A-5fbzA:
undetectable		 3ln1A-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 3ln1B-5fbzA:
undetectable		 3ln1B-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 3ln1C-5fbzA:
undetectable		 3ln1C-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 265
VAL A  76
GLY A  74
ALA A  73
LEU A  33
 None
None
5VV  A   1 ( 4.8A)
None
None
 1.08A 3ln1C-5fbzA:
undetectable		 3ln1C-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 3ln1D-5fbzA:
0.6		 3ln1D-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 265
VAL A  76
GLY A  74
ALA A  73
LEU A  33
 None
None
5VV  A   1 ( 4.8A)
None
None
 1.08A 3ln1D-5fbzA:
0.6		 3ln1D-5fbzA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 GLY A  84
GLY A  74
ILE A 259
ALA A  80
ASP A   2
 5VV  A   1 ( 4.4A)
5VV  A   1 ( 4.8A)
None
None
5VV  A   1 ( 4.7A)
 1.07A 4a6dA-5fbzA:
2.4		 4a6dA-5fbzA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		3 / 3 ILE A   7
ASP A  11
ARG A 188
 None
None
5VV  A   1 ( 3.6A)
 0.83A 4pstA-5fbzA:
undetectable		 4pstA-5fbzA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 5jw1A-5fbzA:
undetectable		 5jw1A-5fbzA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.94A 5jw1B-5fbzA:
undetectable		 5jw1B-5fbzA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.93A 5kirA-5fbzA:
undetectable		 5kirA-5fbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 ALA A 158
VAL A  72
GLY A  74
ALA A  73
LEU A  91
 None
None
5VV  A   1 ( 4.8A)
None
None
 0.96A 5kirB-5fbzA:
undetectable		 5kirB-5fbzA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5fbz ENZYME SUBTILASE
SUBHAL FROM BACILLUS
HALMAPALUS
(Bacillus
halmapalus) 		5 / 12 SER A  75
GLY A 251
GLY A 223
ASN A 161
HIS A  68
 5VV  A   1 ( 2.6A)
None
None
None
None
 1.07A 5kocB-5fbzA:
undetectable		 5kocB-5fbzA:
22.57