SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5RH'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZN_B_SAMB402_0 (UNCHARACTERIZED PROTEIN MJ0883)	5eqi	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 (Homo sapiens)	5 / 12	PHE A 26 PHE A 291 GLY A 31 ILE A 164 PHE A 379	None 5RH A 501 ( 4.9A) None 5RH A 501 (-4.3A) 5RH A 501 ( 4.5A)	1.43A	2zznB-5eqiA: undetectable	2zznB-5eqiA: 20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJJ_B_NCTB501_1 (CYTOCHROME P450 2A6)	5eqi	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 (Homo sapiens)	4 / 7	PHE A 72 PHE A 26 GLY A 134 THR A 137	None None None 5RH A 501 (-2.9A)	1.01A	4ejjB-5eqiA: undetectable	4ejjB-5eqiA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V1F_C_BQ1C1087_0 (F0F1 ATP SYNTHASE SUBUNIT C)	5eqi	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 (Homo sapiens)	3 / 3	GLU A 380 ALA A 377 PHE A 379	5RH A 501 ( 3.6A) None 5RH A 501 ( 4.5A)	0.65A	4v1fC-5eqiA: undetectable	4v1fC-5eqiA: 11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EQP_A_BUWA601_1 (CHOLINESTERASE)	5eqi	SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1 (Homo sapiens)	4 / 8	TRP A 388 GLY A 138 SER A 80 PHE A 26	5RH A 501 (-3.1A) None 5RH A 501 (-2.7A) None	1.04A	6eqpA-5eqiA: undetectable	6eqpA-5eqiA: 9.71

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZZN_B_SAMB402_0","UNCHARACTERIZED PROTEIN MJ0883","5eqi","SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1","Homo sapiens",5,"PHE A  26;PHE A 291;GLY A  31;ILE A 164;PHE A 379","None;5RH A 501 ( 4.9A);None;5RH A 501 (-4.3A);5RH A 501 ( 4.5A)","1.43A","2zznB-5eqiA:undetectable",null],["4EJJ_B_NCTB501_1","CYTOCHROME P450 2A6","5eqi","SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1","Homo sapiens",4,"PHE A  72;PHE A  26;GLY A 134;THR A 137","None;None;None;5RH A 501 (-2.9A)","1.01A","4ejjB-5eqiA:undetectable","2zznB-5eqiA:20.84"],["4V1F_C_BQ1C1087_0","F0F1 ATP SYNTHASE SUBUNIT C","5eqi","SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1","Homo sapiens",3,"GLU A 380;ALA A 377;PHE A 379","5RH A 501 ( 3.6A);None;5RH A 501 ( 4.5A)","0.65A","4v1fC-5eqiA:undetectable","4ejjB-5eqiA:22.22"],["6EQP_A_BUWA601_1","CHOLINESTERASE","5eqi","SOLUTE CARRIER FAMILY 2, FACILITATED GLUCOSE TRANSPORTER MEMBER 1","Homo sapiens",4,"TRP A 388;GLY A 138;SER A  80;PHE A  26","5RH A 501 (-3.1A);None;5RH A 501 (-2.7A);None","1.04A","6eqpA-5eqiA:undetectable","4v1fC-5eqiA:11.41"]]