SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5PZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5ejw CHROMOBOX PROTEIN
HOMOLOG 7
(Mus
musculus) 		3 / 3 SER A  -8
GLY A  -7
ARG A  -3
 None
5PZ  A 101 ( 3.7A)
None
 0.66A 1t9wA-5ejwA:
undetectable		 1t9wA-5ejwA:
5.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5ejw CHROMOBOX PROTEIN
HOMOLOG 7
(Mus
musculus) 		9 / 9 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
HIS A  47
LEU A  49
 None
None
5PZ  A 101 (-3.6A)
5PZ  A 101 (-4.1A)
None
5PZ  A 101 (-3.5A)
None
None
None
 0.68A 4x3uA-5ejwA:
8.4		 4x3uA-5ejwA:
92.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5ejw CHROMOBOX PROTEIN
HOMOLOG 7
(Mus
musculus) 		8 / 10 ARG A  20
LEU A  29
TRP A  32
TRP A  35
TYR A  39
THR A  41
TRP A  42
HIS A  47
 None
None
5PZ  A 101 (-3.6A)
5PZ  A 101 (-4.1A)
None
5PZ  A 101 (-3.5A)
None
None
 0.52A 4x3uB-5ejwA:
8.3		 4x3uB-5ejwA:
92.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X3U_B_SVRB101_2
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5ejw CHROMOBOX PROTEIN
HOMOLOG 7
(Mus
musculus) 		8 / 10 ARG A  20
LEU A  29
TRP A  32
TYR A  39
THR A  41
TRP A  42
HIS A  47
LEU A  49
 None
None
5PZ  A 101 (-3.6A)
None
5PZ  A 101 (-3.5A)
None
None
None
 0.83A 4x3uB-5ejwA:
8.3		 4x3uB-5ejwA:
92.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5ejw CHROMOBOX PROTEIN
HOMOLOG 7
(Mus
musculus) 		4 / 7 VAL A  30
HIS A  47
SER A  -9
THR A  41
 None
None
None
5PZ  A 101 (-3.5A)
 0.97A 5vkqA-5ejwA:
undetectable
5vkqD-5ejwA:
undetectable		 5vkqA-5ejwA:
3.93
5vkqD-5ejwA:
3.93