SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5HY'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIK_A_ADNA699_1 (ADENOSINE KINASE)	3qvl	PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae)	5 / 12	LEU A 148 GLY A 185 GLY A 186 THR A 119 ASN A 12	None 5HY A 1 (-3.8A) None 5HY A 1 (-3.6A) 5HY A 1 (-4.0A)	1.13A	1likA-3qvlA: undetectable	1likA-3qvlA: 23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_C_SAMC2293_0 (GLYCINE N-METHYLTRANSFERASE)	3qvl	PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae)	5 / 12	GLY A 183 THR A 118 ALA A 188 GLY A 81 SER A 79	None 5HY A 1 (-4.4A) None None 5HY A 1 (-3.1A)	1.31A	1nbiC-3qvlA: undetectable	1nbiC-3qvlA: 24.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD3_A_CHDA502_0 (FERROCHELATASE)	3qvl	PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae)	4 / 8	PRO A 83 SER A 79 VAL A 58 GLY A 59	None 5HY A 1 (-3.1A) None None	1.04A	2qd3A-3qvlA: 3.4	2qd3A-3qvlA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OGP_A_017A200_2 (FIV PROTEASE)	3qvl	PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae)	5 / 10	LEU A 85 ASP A 82 ALA A 100 GLY A 185 ILE A 21	None None None 5HY A 1 (-3.8A) None	1.28A	3ogpB-3qvlA: undetectable	3ogpB-3qvlA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MK4_A_CHDA504_0 (FERROCHELATASE, MITOCHONDRIAL)	3qvl	PUTATIVE HYDANTOIN RACEMASE (Klebsiella pneumoniae)	4 / 8	PRO A 83 SER A 79 VAL A 58 GLY A 59	None 5HY A 1 (-3.1A) None None	0.95A	4mk4A-3qvlA: 3.7	4mk4A-3qvlA: 20.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LIK_A_ADNA699_1","ADENOSINE KINASE","3qvl","PUTATIVE HYDANTOIN RACEMASE","Klebsiella pneumoniae",5,"LEU A 148;GLY A 185;GLY A 186;THR A 119;ASN A  12","None;5HY A   1 (-3.8A);None;5HY A   1 (-3.6A);5HY A   1 (-4.0A)","1.13A","1likA-3qvlA:undetectable",null],["1NBI_C_SAMC2293_0","GLYCINE N-METHYLTRANSFERASE","3qvl","PUTATIVE HYDANTOIN RACEMASE","Klebsiella pneumoniae",5,"GLY A 183;THR A 118;ALA A 188;GLY A  81;SER A  79","None;5HY A   1 (-4.4A);None;None;5HY A   1 (-3.1A)","1.31A","1nbiC-3qvlA:undetectable","1likA-3qvlA:23.75"],["2QD3_A_CHDA502_0","FERROCHELATASE","3qvl","PUTATIVE HYDANTOIN RACEMASE","Klebsiella pneumoniae",4,"PRO A  83;SER A  79;VAL A  58;GLY A  59","None;5HY A   1 (-3.1A);None;None","1.04A","2qd3A-3qvlA:3.4","1nbiC-3qvlA:24.50"],["3OGP_A_017A200_2","FIV PROTEASE;FIV PROTEASE","3qvl","PUTATIVE HYDANTOIN RACEMASE","Klebsiella pneumoniae",5,"LEU A  85;ASP A  82;ALA A 100;GLY A 185;ILE A  21","None;None;None;5HY A   1 (-3.8A);None","1.28A","3ogpB-3qvlA:undetectable","2qd3A-3qvlA:20.92"],["4MK4_A_CHDA504_0","FERROCHELATASE, MITOCHONDRIAL","3qvl","PUTATIVE HYDANTOIN RACEMASE","Klebsiella pneumoniae",4,"PRO A  83;SER A  79;VAL A  58;GLY A  59","None;5HY A   1 (-3.1A);None;None","0.95A","4mk4A-3qvlA:3.7","3ogpB-3qvlA:21.30"]]