SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5F7'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1NW3_A_SAMA500_0 (HISTONE METHYLTRANSFERASE DOT1L)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	10 / 12	ASP A 161 GLY A 163 VAL A 169 LYS A 187 ALA A 188 PHE A 223 LEU A 224 PHE A 239 ASN A 241 PHE A 245	None None None None None None None 5F7  A 401 (-3.9A) 5F7  A 401 (-3.6A) None	0.48A	1nw3A-5dtrA: 39.8	1nw3A-5dtrA: 92.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NXE_B_SAMB303_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	5 / 12	ASP A 161 LEU A 162 GLY A 163 GLY A 165 ASN A 241	None None None None 5F7  A 401 (-3.6A)	0.64A	2nxeB-5dtrA: 11.1	2nxeB-5dtrA: 21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DXY_A_SAMA1_0 (TRNA (GUANINE-N(7)-)-METH YLTRANSFERASE)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	5 / 11	GLY A 163 GLY A 165 GLU A 186 ASP A 222 PHE A 131	None None None None 5F7  A 401 (-4.4A)	0.97A	3dxyA-5dtrA: 9.4	3dxyA-5dtrA: 19.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3QOW_A_SAMA417_0 (HISTONE-LYSINE N-METHYLTRANSFERASE)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	8 / 12	GLY A 163 VAL A 169 LYS A 187 ALA A 188 ASP A 222 PHE A 223 ASN A 241 PHE A 245	None None None None None None 5F7  A 401 (-3.6A) None	0.55A	3qowA-5dtrA: 39.1	3qowA-5dtrA: 92.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4B_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	4 / 8	PHE A 159 THR A 177 VAL A 144 VAL A 267	None None 5F7  A 401 ( 4.6A) 5F7  A 401 (-4.5A)	0.93A	4l4bA-5dtrA: undetectable	4l4bA-5dtrA: 20.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MVS_A_ADNA401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	7 / 7	GLY A 163 GLU A 186 LYS A 187 ALA A 188 ASP A 222 PHE A 223 ASN A 241	None None None None None None 5F7  A 401 (-3.6A)	0.43A	5mvsA-5dtrA: 47.7	5mvsA-5dtrA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MVS_B_ADNB401_1 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	8 / 8	GLY A 163 GLU A 186 LYS A 187 ALA A 188 ASP A 222 PHE A 223 ASN A 241 PHE A 245	None None None None None None 5F7  A 401 (-3.6A) None	0.27A	5mvsB-5dtrA: 46.9	5mvsB-5dtrA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_A_SAMA601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	5 / 12	GLY A 165 LYS A 187 PRO A 191 LEU A 224 ASN A 241	None None None None 5F7  A 401 (-3.6A)	0.97A	5ybbA-5dtrA: 8.2	5ybbA-5dtrA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_B_SAMB601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	5 / 12	ASP A 161 LYS A 187 PRO A 191 LEU A 224 ASN A 241	None None None None 5F7  A 401 (-3.6A)	0.84A	5ybbB-5dtrA: 7.0	5ybbB-5dtrA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YBB_B_SAMB601_0 (TYPE I RESTRICTION-MODIFICA TION SYSTEM METHYLTRANSFERASE SUBUNIT)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	5 / 12	ASP A 161 PRO A 191 LEU A 224 ASN A 241 PHE A 223	None None None 5F7  A 401 (-3.6A) None	1.41A	5ybbB-5dtrA: 7.0	5ybbB-5dtrA: 21.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6NJ9_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	9 / 12	ASP A 161 GLY A 163 GLY A 165 VAL A 169 LYS A 187 ALA A 188 ASP A 222 PHE A 223 PHE A 239	None None None None None None None None 5F7  A 401 (-3.9A)	0.57A	6nj9K-5dtrA: 35.0	6nj9K-5dtrA: 92.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6NQA_K_SAMK500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC)	5dtr	HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-79 SPECIFIC (Homo sapiens)	7 / 10	ASP A 161 GLY A 163 GLY A 165 VAL A 169 LYS A 187 ASN A 241 PHE A 245	None None None None None 5F7  A 401 (-3.6A) None	0.80A	6nqaK-5dtrA: 33.5	6nqaK-5dtrA: 92.50