SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5DA'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5dm4 METHYLTRANSFERASE
DOMAIN FAMILY
(Bacillus
pumilus) 		5 / 12 ILE A   2
ILE A   6
GLY A 133
LEU A 250
LEU A 198
 None
None
5DA  A 302 (-3.5A)
None
None
 1.07A 3em0B-5dm4A:
undetectable		 3em0B-5dm4A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 5dm4 METHYLTRANSFERASE
DOMAIN FAMILY
(Bacillus
pumilus) 		4 / 5 LYS A 248
SER A 192
LEU A 160
SER A 188
 None
None
5DA  A 302 ( 4.5A)
5DA  A 302 (-2.8A)
 1.43A 3ijxH-5dm4A:
undetectable		 3ijxH-5dm4A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5dm4 METHYLTRANSFERASE
DOMAIN FAMILY
(Bacillus
pumilus) 		5 / 12 GLY A 133
PHE A 135
ILE A 201
THR A 202
LEU A 254
 5DA  A 302 (-3.5A)
SAH  A 300 ( 4.6A)
None
None
None
 0.96A 4n49A-5dm4A:
6.8		 4n49A-5dm4A:
20.54