SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5D7'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 5dly PLANTAZOLICIN
METHYLTRANSFERASE
BAML
(Bacillus
velezensis) 		3 / 3 TYR A 187
TYR A  33
GLY A 170
 None
5D7  A 300 (-4.8A)
None
 0.52A 3eteB-5dlyA:
4.0
3eteD-5dlyA:
3.8
3eteF-5dlyA:
2.2		 3eteB-5dlyA:
19.52
3eteD-5dlyA:
19.52
3eteF-5dlyA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 5dly PLANTAZOLICIN
METHYLTRANSFERASE
BAML
(Bacillus
velezensis) 		5 / 12 ILE A 143
LEU A 200
ASP A 161
GLY A 135
ILE A 130
 None
None
5D7  A 300 (-2.8A)
5D7  A 300 (-3.5A)
None
 1.06A 5j7wD-5dlyA:
undetectable		 5j7wD-5dlyA:
20.18