SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '59Q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MG0_K_BO2K1402_1 (PROTEASOME COMPONENT PRE2 PROTEASOME COMPONENT C5)	5ddb	MENIN (Homo sapiens)	5 / 11	ALA A 158 ALA A 182 VAL A 196 ALA A 164 GLY A 163	None 59Q A 601 (-3.7A) None None None	0.89A	3mg0K-5ddbA: undetectable 3mg0L-5ddbA: undetectable	3mg0K-5ddbA: 17.41 3mg0L-5ddbA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_B_MRVB1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	5ddb	MENIN (Homo sapiens)	4 / 5	TYR A 361 LEU A 413 THR A 344 MET A 322	PG4 A 604 ( 4.6A) None None 59Q A 601 (-4.4A)	1.48A	4mbsB-5ddbA: undetectable	4mbsB-5ddbA: 21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_C_SAMC902_0 (MRNA CAPPING ENZYME P5)	5ddb	MENIN (Homo sapiens)	5 / 12	LEU A 177 GLY A 156 ALA A 182 ASP A 153 PHE A 146	59Q A 601 (-3.8A) None 59Q A 601 (-3.7A) None None	1.28A	5x6yC-5ddbA: undetectable	5x6yC-5ddbA: 21.31