SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '56L'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZUL_A_SAMA376_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	5 / 12	TYR A 117 GLY A 46 GLY A 44 ALA A 42 VAL A 139	None 56L A 205 (-3.7A) None None None	1.05A	2zulA-5cx0A: undetectable	2zulA-5cx0A: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMF_A_SAMA388_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	5 / 12	TYR A 117 GLY A 46 GLY A 44 ALA A 42 VAL A 139	None 56L A 205 (-3.7A) None None None	1.08A	3dmfA-5cx0A: undetectable	3dmfA-5cx0A: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DMH_A_SAMA384_0 (PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	5 / 12	TYR A 117 GLY A 46 GLY A 44 ALA A 42 VAL A 139	None 56L A 205 (-3.7A) None None None	1.08A	3dmhA-5cx0A: undetectable	3dmhA-5cx0A: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LXZ_A_SHHA407_1 (HISTONE DEACETYLASE 2)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	5 / 12	PRO A 152 GLY A 162 PHE A 161 GLY A 98 TYR A 151	None None None 56L A 205 (-3.5A) None	1.18A	4lxzA-5cx0A: undetectable	4lxzA-5cx0A: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LXZ_C_SHHC406_1 (HISTONE DEACETYLASE 2)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	5 / 12	PRO A 152 GLY A 162 PHE A 161 GLY A 98 TYR A 151	None None None 56L A 205 (-3.5A) None	1.16A	4lxzC-5cx0A: undetectable	4lxzC-5cx0A: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UUN_A_ACTA310_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN)	5cx0	PEPTIDE DEFORMYLASE (Xanthomonas oryzae)	3 / 3	GLU A 142 HIS A 141 ARG A 137	56L A 205 (-3.3A) CD A 201 ( 3.5A) None	0.94A	5uunA-5cx0A: undetectable	5uunA-5cx0A: 22.49

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2ZUL_A_SAMA376_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",5,"TYR A 117;GLY A  46;GLY A  44;ALA A  42;VAL A 139","None;56L A 205 (-3.7A);None;None;None","1.05A","2zulA-5cx0A:undetectable",null],["3DMF_A_SAMA388_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",5,"TYR A 117;GLY A  46;GLY A  44;ALA A  42;VAL A 139","None;56L A 205 (-3.7A);None;None;None","1.08A","3dmfA-5cx0A:undetectable","2zulA-5cx0A:19.24"],["3DMH_A_SAMA384_0","PROBABLE RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",5,"TYR A 117;GLY A  46;GLY A  44;ALA A  42;VAL A 139","None;56L A 205 (-3.7A);None;None;None","1.08A","3dmhA-5cx0A:undetectable","3dmfA-5cx0A:19.24"],["4LXZ_A_SHHA407_1","HISTONE DEACETYLASE 2","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",5,"PRO A 152;GLY A 162;PHE A 161;GLY A  98;TYR A 151","None;None;None;56L A 205 (-3.5A);None","1.18A","4lxzA-5cx0A:undetectable","3dmhA-5cx0A:19.24"],["4LXZ_C_SHHC406_1","HISTONE DEACETYLASE 2","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",5,"PRO A 152;GLY A 162;PHE A 161;GLY A  98;TYR A 151","None;None;None;56L A 205 (-3.5A);None","1.16A","4lxzC-5cx0A:undetectable","4lxzA-5cx0A:18.96"],["5UUN_A_ACTA310_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN","5cx0","PEPTIDE DEFORMYLASE","Xanthomonas oryzae",3,"GLU A 142;HIS A 141;ARG A 137","56L A 205 (-3.3A); CD A 201 ( 3.5A);None","0.94A","5uunA-5cx0A:undetectable","4lxzC-5cx0A:18.96"]]