SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '539'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E3V_A_DXCA801_0 (STEROID DELTA-ISOMERASE)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	TYR B 307 PHE B 281 VAL B 291 LEU B 227 ALA B 269	539 B 403 ( 3.9A) 539 B 403 (-3.5A) None None 539 B 403 ( 4.0A)	1.48A	1e3vA-5cprB: undetectable	1e3vA-5cprB: 17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FO4_B_SALB4005_1 (XANTHINE DEHYDROGENASE)	5t77	PUTATIVE LIPID II FLIPPASE MURJ (Thermosipho africanus)	4 / 7	PHE A 364 THR A 224 VAL A 227 ALA A 367	OLC A 529 (-3.1A) OLC A 539 ( 2.5A) OLC A 530 ( 4.5A) OLC A 530 (-2.9A)	1.09A	1fo4B-5t77A: undetectable	1fo4B-5t77A: 16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NSI_B_H4BB601_1 (PROTEIN (NITRIC OXIDE SYNTHASE))	3c2u	XYLOSIDASE/ARABINOSI DASE (Selenomonas ruminantium)	4 / 6	GLU A 32 ARG A 290 ILE A 72 TRP A 73	None B3P A 539 (-2.7A) None B3P A 539 (-4.6A)	1.48A	1nsiA-3c2uA: undetectable 1nsiB-3c2uA: undetectable	1nsiA-3c2uA: 22.59 1nsiB-3c2uA: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_I_BEZI518_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	5gpr	CHITINASE (Ostrinia furnacalis)	4 / 7	ILE A 541 GLY A 539 ASN A 176 ASN A 142	ILE A 541 ( 0.7A) GLY A 539 ( 0.0A) ASN A 176 ( 0.6A) ASN A 142 ( 0.6A)	1.01A	1oniG-5gprA: undetectable 1oniI-5gprA: 0.8	1oniG-5gprA: 14.23 1oniI-5gprA: 14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S3Z_B_RIOB501_0 (AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERA SE)	3fnr	ARGINYL-TRNA SYNTHETASE (Campylobacter jejuni)	4 / 8	TYR A 149 ARG A 307 GLU A 109 ASP A 297	None None None GOL A 539 (-3.4A)	1.18A	1s3zA-3fnrA: undetectable 1s3zB-3fnrA: undetectable	1s3zA-3fnrA: 14.81 1s3zB-3fnrA: 14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_A_SAMA801_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 10	SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312	SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A)	1.33A	2h21A-5cprB: 6.4	2h21A-5cprB: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_B_SAMB802_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 11	SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312	SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A)	1.33A	2h21B-5cprB: 5.7	2h21B-5cprB: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H21_C_SAMC803_0 (RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE/OXYGENAS E)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 11	SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312	SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A)	1.32A	2h21C-5cprB: 5.9	2h21C-5cprB: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IEO_A_017A402_2 (PROTEASE)	3igo	CALMODULIN-DOMAIN PROTEIN KINASE 1 (Cryptosporidium parvum)	5 / 12	LEU A 91 ASP A 95 VAL A 151 VAL A 106 VAL A 104	None GOL A 539 (-3.7A) None None None	0.89A	2ieoB-3igoA: undetectable	2ieoB-3igoA: 9.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HBB_B_TMQB612_1 (DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 9	ALA B 268 ILE B 184 THR B 85 PHE B 144 ILE B 197	539 B 403 (-3.6A) None None None None	1.43A	3hbbB-5cprB: undetectable	3hbbB-5cprB: 20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MB5_A_SAMA301_1 (SAM-DEPENDENT METHYLTRANSFERASE)	5gpr	CHITINASE (Ostrinia furnacalis)	4 / 4	GLY A 539 GLU A 140 ASP A 535 ASP A 540	GLY A 539 ( 0.0A) GLU A 140 ( 0.6A) ASP A 535 ( 0.6A) ASP A 540 ( 0.5A)	1.26A	3mb5A-5gprA: undetectable	3mb5A-5gprA: 19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OOI_A_SAMA237_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.39A	3ooiA-5cprB: 7.7	3ooiA-5cprB: 24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R24_A_SAMA302_0 (2'-O-METHYL TRANSFERASE)	4aie	GLUCAN 1,6-ALPHA-GLUCOSIDAS E (Lactobacillus acidophilus)	5 / 12	GLY A 325 SER A 497 PRO A 529 LEU A 285 ASP A 272	None None MES A1539 (-4.1A) None None	1.36A	3r24A-4aieA: undetectable	3r24A-4aieA: undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RQ4_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	GLY B 246 SER B 251 HIS B 273 TYR B 307 CYH B 319	None SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A)	1.43A	3rq4A-5cprB: 33.6	3rq4A-5cprB: 58.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RQ4_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 GLU B 206 GLY B 209 SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.19A	3rq4A-5cprB: 33.6	3rq4A-5cprB: 58.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3RQ4_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	8 / 12	TYR B 203 GLU B 206 GLY B 209 SER B 251 HIS B 273 TYR B 307 CYH B 321 GLU B 320	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.2A) SAM B 402 (-4.6A)	1.42A	3rq4A-5cprB: 33.6	3rq4A-5cprB: 58.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S8P_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 GLY B 209 ALA B 210 PHE B 250 ASN B 272 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.25A	3s8pA-5cprB: 38.0	3s8pA-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S8P_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 GLY B 209 ALA B 210 SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.46A	3s8pA-5cprB: 38.0	3s8pA-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S8P_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 GLU B 206 GLY B 209 ALA B 210 PHE B 250 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.26A	3s8pB-5cprB: 35.7	3s8pB-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S8P_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 GLU B 206 GLY B 209 ALA B 210 SER B 251 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.46A	3s8pB-5cprB: 35.7	3s8pB-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3S8P_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	8 / 12	TYR B 203 GLU B 206 GLY B 209 PHE B 250 HIS B 273 TYR B 307 GLU B 320 CYH B 319	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-4.6A) ZN B 401 ( 2.3A)	1.41A	3s8pB-5cprB: 35.7	3s8pB-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BUP_A_SAMA500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	12 / 12	TYR B 203 GLU B 206 GLY B 209 ALA B 210 SER B 251 ASN B 272 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.49A	4bupA-5cprB: 36.0	4bupA-5cprB: 98.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BUP_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	7 / 12	TYR B 203 GLY B 209 PHE B 250 HIS B 273 TYR B 307 GLU B 320 CYH B 319	SAM B 402 (-3.7A) SAM B 402 (-3.4A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-4.6A) ZN B 401 ( 2.3A)	1.48A	4bupB-5cprB: 37.4	4bupB-5cprB: 98.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BUP_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 PHE B 250 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.31A	4bupB-5cprB: 37.4	4bupB-5cprB: 98.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BUP_B_SAMB500_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 SER B 251 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.51A	4bupB-5cprB: 37.4	4bupB-5cprB: 98.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_D_H4BD600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	3c2u	XYLOSIDASE/ARABINOSI DASE (Selenomonas ruminantium)	4 / 7	GLU A 32 ARG A 290 ILE A 72 TRP A 73	None B3P A 539 (-2.7A) None B3P A 539 (-4.6A)	1.48A	4cx7C-3c2uA: undetectable 4cx7D-3c2uA: undetectable	4cx7C-3c2uA: 22.59 4cx7D-3c2uA: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NOS_B_H4BB1011_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3c2u	XYLOSIDASE/ARABINOSI DASE (Selenomonas ruminantium)	4 / 7	GLU A 32 ARG A 290 ILE A 72 TRP A 73	None B3P A 539 (-2.7A) None B3P A 539 (-4.6A)	1.48A	4nosA-3c2uA: undetectable 4nosB-3c2uA: undetectable	4nosA-3c2uA: 20.97 4nosB-3c2uA: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NOS_C_H4BC2011_1 (INDUCIBLE NITRIC OXIDE SYNTHASE)	3c2u	XYLOSIDASE/ARABINOSI DASE (Selenomonas ruminantium)	4 / 7	ARG A 290 ILE A 72 TRP A 73 GLU A 32	B3P A 539 (-2.7A) None B3P A 539 (-4.6A) None	1.46A	4nosC-3c2uA: undetectable 4nosD-3c2uA: undetectable	4nosC-3c2uA: 20.97 4nosD-3c2uA: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UXQ_A_0LIA1752_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	4bqh	UDP-N-ACETYLGLUCOSAM INE PYROPHOSPHORYLASE (Trypanosoma brucei)	4 / 7	VAL A 45 ILE A 219 ARG A 380 ILE A 220	9VU A1539 (-3.9A) None None None	0.66A	4uxqA-4bqhA: undetectable	4uxqA-4bqhA: 20.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5CPR_B_SAMB402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	12 / 12	TYR B 203 GLU B 206 GLY B 209 ALA B 210 PHE B 250 SER B 251 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.9A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.01A	5cprB-5cprB: 41.8	5cprB-5cprB: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DPD_A_SAMA601_0 (PROTEIN LYSINE METHYLTRANSFERASE 1)	4bqh	UDP-N-ACETYLGLUCOSAM INE PYROPHOSPHORYLASE (Trypanosoma brucei)	5 / 12	GLU A 396 GLY A 232 SER A 177 VAL A 209 VAL A 45	None 9VU A1539 (-3.2A) None 9VU A1539 (-4.9A) 9VU A1539 (-3.9A)	1.14A	5dpdA-4bqhA: 2.2	5dpdA-4bqhA: 22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HFJ_C_SAMC301_1 (ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA))	3c2u	XYLOSIDASE/ARABINOSI DASE (Selenomonas ruminantium)	4 / 4	ASP A 14 HIS A 189 SER A 250 GLU A 212	B3P A 539 (-2.7A) None None None	1.23A	5hfjC-3c2uA: 0.0	5hfjC-3c2uA: 17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LSU_B_SAMB1304_1 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD2)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	3 / 3	ASN B 272 TYR B 307 CYH B 319	SAM B 402 (-3.1A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A)	0.43A	5lsuB-5cprB: 7.3	5lsuB-5cprB: 24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UPD_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 11	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.53A	5updA-5cprB: 7.4	5updA-5cprB: 24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCV_A_1N1A404_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	3rx8	CELLULASE (Alicyclobacillus acidocaldarius)	4 / 5	VAL A 518 LEU A 103 CYH A 104 ASP A 146	None None ZN A 539 (-2.3A) 9MR A 601 ( 2.9A)	1.23A	5vcvA-3rx8A: undetectable	5vcvA-3rx8A: 22.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5WBV_A_SAMA402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 PHE B 250 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.49A	5wbvA-5cprB: 37.6	5wbvA-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5WBV_A_SAMA402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 SER B 251 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.60A	5wbvA-5cprB: 37.6	5wbvA-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5WBV_B_SAMB402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 PHE B 250 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) None SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.48A	5wbvB-5cprB: 35.5	5wbvB-5cprB: 97.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5WBV_B_SAMB402_0 (HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	11 / 12	TYR B 203 SER B 205 GLY B 209 ALA B 210 SER B 251 HIS B 273 TYR B 307 PHE B 312 CYH B 319 GLU B 320 CYH B 321	SAM B 402 (-3.7A) SAM B 402 (-2.7A) SAM B 402 (-3.4A) SAM B 402 (-3.9A) SAM B 402 (-3.9A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) SAM B 402 (-3.7A) ZN B 401 ( 2.3A) SAM B 402 (-4.6A) ZN B 401 ( 2.2A)	0.59A	5wbvB-5cprB: 35.5	5wbvB-5cprB: 97.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5K_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.42A	6a5kA-5cprB: 8.3	6a5kA-5cprB: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5M_A_SAMA805_0 (HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.38A	6a5mA-5cprB: undetectable	6a5mA-5cprB: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AGO_A_SAMA2301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 11	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.87A	6agoA-5cprB: 7.8	6agoA-5cprB: 26.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CEN_A_SAMA1301_0 (HISTONE-LYSINE N-METHYLTRANSFERASE NSD3)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 11	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.53A	6cenA-5cprB: 7.4	6cenA-5cprB: 23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNG_B_QPSB601_3 (-)	3fnr	ARGINYL-TRNA SYNTHETASE (Campylobacter jejuni)	3 / 3	ASP A 278 ASP A 297 ASN A 114	None GOL A 539 (-3.4A) None	0.75A	6gngB-3fnrA: 3.0	6gngB-3fnrA: 21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6INE_A_SAMA2304_0 (HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L)	5cpr	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 (Homo sapiens)	5 / 12	ASN B 272 HIS B 273 TYR B 307 CYH B 319 CYH B 321	SAM B 402 (-3.1A) SAM B 402 (-4.5A) 539 B 403 ( 3.9A) ZN B 401 ( 2.3A) ZN B 401 ( 2.2A)	0.49A	6ineA-5cprB: 7.5	6ineA-5cprB: 25.33

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E3V_A_DXCA801_0","STEROID DELTA-ISOMERASE","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"TYR B 307;PHE B 281;VAL B 291;LEU B 227;ALA B 269","539 B 403 ( 3.9A);539 B 403 (-3.5A);None;None;539 B 403 ( 4.0A)","1.48A","1e3vA-5cprB:undetectable",null],["1FO4_B_SALB4005_1","XANTHINE DEHYDROGENASE","5t77","PUTATIVE LIPID II FLIPPASE MURJ","Thermosipho africanus",4,"PHE A 364;THR A 224;VAL A 227;ALA A 367","OLC A 529 (-3.1A);OLC A 539 ( 2.5A);OLC A 530 ( 4.5A);OLC A 530 (-2.9A)","1.09A","1fo4B-5t77A:undetectable","1e3vA-5cprB:17.09"],["1NSI_B_H4BB601_1","PROTEIN (NITRIC OXIDE SYNTHASE);PROTEIN (NITRIC OXIDE SYNTHASE)","3c2u","XYLOSIDASE\/ARABINOSIDASE","Selenomonas ruminantium",4,"GLU A  32;ARG A 290;ILE A  72;TRP A  73","None;B3P A 539 (-2.7A);None;B3P A 539 (-4.6A)","1.48A","1nsiA-3c2uA:undetectable;1nsiB-3c2uA:undetectable","1fo4B-5t77A:16.39"],["1ONI_I_BEZI518_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","5gpr","CHITINASE","Ostrinia furnacalis",4,"ILE A 541;GLY A 539;ASN A 176;ASN A 142","ILE A 541 ( 0.7A);GLY A 539 ( 0.0A);ASN A 176 ( 0.6A);ASN A 142 ( 0.6A)","1.01A","1oniG-5gprA:undetectable;1oniI-5gprA:0.8","1nsiA-3c2uA:22.59;1nsiB-3c2uA:22.59"],["1S3Z_B_RIOB501_0","AMINOGLYCOSIDE 6'-N-ACETYLTRANSFERASE","3fnr","ARGINYL-TRNA SYNTHETASE","Campylobacter jejuni",4,"TYR A 149;ARG A 307;GLU A 109;ASP A 297","None;None;None;GOL A 539 (-3.4A)","1.18A","1s3zA-3fnrA:undetectable;1s3zB-3fnrA:undetectable","1oniG-5gprA:14.23;1oniI-5gprA:14.23"],["2H21_A_SAMA801_0","RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE\/OXYGENASE","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312","SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A)","1.33A","2h21A-5cprB:6.4","1s3zA-3fnrA:14.81;1s3zB-3fnrA:14.81"],["2H21_B_SAMB802_0","RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE\/OXYGENASE","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312","SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A)","1.33A","2h21B-5cprB:5.7","2h21A-5cprB:21.35"],["2H21_C_SAMC803_0","RIBULOSE-1,5 BISPHOSPHATE CARBOXYLASE\/OXYGENASE","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312","SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A)","1.32A","2h21C-5cprB:5.9","2h21B-5cprB:21.35"],["2IEO_A_017A402_2","PROTEASE;PROTEASE","3igo","CALMODULIN-DOMAIN PROTEIN KINASE 1","Cryptosporidium parvum",5,"LEU A  91;ASP A  95;VAL A 151;VAL A 106;VAL A 104","None;GOL A 539 (-3.7A);None;None;None","0.89A","2ieoB-3igoA:undetectable","2h21C-5cprB:21.35"],["3HBB_B_TMQB612_1","DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ALA B 268;ILE B 184;THR B  85;PHE B 144;ILE B 197","539 B 403 (-3.6A);None;None;None;None","1.43A","3hbbB-5cprB:undetectable","2ieoB-3igoA:9.75"],["3MB5_A_SAMA301_1","SAM-DEPENDENT METHYLTRANSFERASE","5gpr","CHITINASE","Ostrinia furnacalis",4,"GLY A 539;GLU A 140;ASP A 535;ASP A 540","GLY A 539 ( 0.0A);GLU A 140 ( 0.6A);ASP A 535 ( 0.6A);ASP A 540 ( 0.5A)","1.26A","3mb5A-5gprA:undetectable","3hbbB-5cprB:20.61"],["3OOI_A_SAMA237_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-36 AND H4 LYSINE-20 SPECIFIC","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.39A","3ooiA-5cprB:7.7","3mb5A-5gprA:19.86"],["3R24_A_SAMA302_0","2'-O-METHYL TRANSFERASE","4aie","GLUCAN 1,6-ALPHA-GLUCOSIDASE","Lactobacillus acidophilus",5,"GLY A 325;SER A 497;PRO A 529;LEU A 285;ASP A 272","None;None;MES A1539 (-4.1A);None;None","1.36A","3r24A-4aieA:undetectable","3ooiA-5cprB:24.91"],["3RQ4_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"GLY B 246;SER B 251;HIS B 273;TYR B 307;CYH B 319","None;SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A)","1.43A","3rq4A-5cprB:33.6","3r24A-4aieA:undetectable"],["3RQ4_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;GLU B 206;GLY B 209;SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.19A","3rq4A-5cprB:33.6","3rq4A-5cprB:58.96"],["3RQ4_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",8,"TYR B 203;GLU B 206;GLY B 209;SER B 251;HIS B 273;TYR B 307;CYH B 321;GLU B 320","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.2A);SAM B 402 (-4.6A)","1.42A","3rq4A-5cprB:33.6","3rq4A-5cprB:58.96"],["3S8P_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;GLY B 209;ALA B 210;PHE B 250;ASN B 272;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.25A","3s8pA-5cprB:38.0","3rq4A-5cprB:58.96"],["3S8P_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;GLY B 209;ALA B 210;SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.46A","3s8pA-5cprB:38.0","3s8pA-5cprB:97.80"],["3S8P_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;GLU B 206;GLY B 209;ALA B 210;PHE B 250;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.26A","3s8pB-5cprB:35.7","3s8pA-5cprB:97.80"],["3S8P_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;GLU B 206;GLY B 209;ALA B 210;SER B 251;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.46A","3s8pB-5cprB:35.7","3s8pB-5cprB:97.80"],["3S8P_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",8,"TYR B 203;GLU B 206;GLY B 209;PHE B 250;HIS B 273;TYR B 307;GLU B 320;CYH B 319","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-4.6A); ZN B 401 ( 2.3A)","1.41A","3s8pB-5cprB:35.7","3s8pB-5cprB:97.80"],["4BUP_A_SAMA500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",12,"TYR B 203;GLU B 206;GLY B 209;ALA B 210;SER B 251;ASN B 272;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.49A","4bupA-5cprB:36.0","3s8pB-5cprB:97.80"],["4BUP_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",7,"TYR B 203;GLY B 209;PHE B 250;HIS B 273;TYR B 307;GLU B 320;CYH B 319","SAM B 402 (-3.7A);SAM B 402 (-3.4A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-4.6A); ZN B 401 ( 2.3A)","1.48A","4bupB-5cprB:37.4","4bupA-5cprB:98.15"],["4BUP_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;PHE B 250;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.31A","4bupB-5cprB:37.4","4bupB-5cprB:98.15"],["4BUP_B_SAMB500_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;SER B 251;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.51A","4bupB-5cprB:37.4","4bupB-5cprB:98.15"],["4CX7_D_H4BD600_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","3c2u","XYLOSIDASE\/ARABINOSIDASE","Selenomonas ruminantium",4,"GLU A  32;ARG A 290;ILE A  72;TRP A  73","None;B3P A 539 (-2.7A);None;B3P A 539 (-4.6A)","1.48A","4cx7C-3c2uA:undetectable;4cx7D-3c2uA:undetectable","4bupB-5cprB:98.15"],["4NOS_B_H4BB1011_1","INDUCIBLE NITRIC OXIDE SYNTHASE;INDUCIBLE NITRIC OXIDE SYNTHASE","3c2u","XYLOSIDASE\/ARABINOSIDASE","Selenomonas ruminantium",4,"GLU A  32;ARG A 290;ILE A  72;TRP A  73","None;B3P A 539 (-2.7A);None;B3P A 539 (-4.6A)","1.48A","4nosA-3c2uA:undetectable;4nosB-3c2uA:undetectable","4cx7C-3c2uA:22.59;4cx7D-3c2uA:22.59"],["4NOS_C_H4BC2011_1","INDUCIBLE NITRIC OXIDE SYNTHASE;INDUCIBLE NITRIC OXIDE SYNTHASE","3c2u","XYLOSIDASE\/ARABINOSIDASE","Selenomonas ruminantium",4,"ARG A 290;ILE A  72;TRP A  73;GLU A  32","B3P A 539 (-2.7A);None;B3P A 539 (-4.6A);None","1.46A","4nosC-3c2uA:undetectable;4nosD-3c2uA:undetectable","4nosA-3c2uA:20.97;4nosB-3c2uA:20.97"],["4UXQ_A_0LIA1752_2","FIBROBLAST GROWTH FACTOR RECEPTOR 4","4bqh","UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE","Trypanosoma brucei",4,"VAL A  45;ILE A 219;ARG A 380;ILE A 220","9VU A1539 (-3.9A);None;None;None","0.66A","4uxqA-4bqhA:undetectable","4nosC-3c2uA:20.97;4nosD-3c2uA:20.97"],["5CPR_B_SAMB402_0","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",12,"TYR B 203;GLU B 206;GLY B 209;ALA B 210;PHE B 250;SER B 251;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.9A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.01A","5cprB-5cprB:41.8","4uxqA-4bqhA:20.54"],["5DPD_A_SAMA601_0","PROTEIN LYSINE METHYLTRANSFERASE 1","4bqh","UDP-N-ACETYLGLUCOSAMINE PYROPHOSPHORYLASE","Trypanosoma brucei",5,"GLU A 396;GLY A 232;SER A 177;VAL A 209;VAL A  45","None;9VU A1539 (-3.2A);None;9VU A1539 (-4.9A);9VU A1539 (-3.9A)","1.14A","5dpdA-4bqhA:2.2","5cprB-5cprB:100.00"],["5HFJ_C_SAMC301_1","ADENINE SPECIFIC DNA METHYLTRANSFERASE (DPNA)","3c2u","XYLOSIDASE\/ARABINOSIDASE","Selenomonas ruminantium",4,"ASP A  14;HIS A 189;SER A 250;GLU A 212","B3P A 539 (-2.7A);None;None;None","1.23A","5hfjC-3c2uA:0.0","5dpdA-4bqhA:22.58"],["5LSU_B_SAMB1304_1","HISTONE-LYSINE N-METHYLTRANSFERASE NSD2","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",3,"ASN B 272;TYR B 307;CYH B 319","SAM B 402 (-3.1A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A)","0.43A","5lsuB-5cprB:7.3","5hfjC-3c2uA:17.47"],["5UPD_A_SAMA1301_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD3","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.53A","5updA-5cprB:7.4","5lsuB-5cprB:24.48"],["5VCV_A_1N1A404_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","3rx8","CELLULASE","Alicyclobacillus acidocaldarius",4,"VAL A 518;LEU A 103;CYH A 104;ASP A 146","None;None; ZN A 539 (-2.3A);9MR A 601 ( 2.9A)","1.23A","5vcvA-3rx8A:undetectable","5updA-5cprB:24.47"],["5WBV_A_SAMA402_0","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;PHE B 250;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.49A","5wbvA-5cprB:37.6","5vcvA-3rx8A:22.24"],["5WBV_A_SAMA402_0","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;SER B 251;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.60A","5wbvA-5cprB:37.6","5wbvA-5cprB:97.80"],["5WBV_B_SAMB402_0","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;PHE B 250;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);None;SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.48A","5wbvB-5cprB:35.5","5wbvA-5cprB:97.80"],["5WBV_B_SAMB402_0","HISTONE-LYSINE N-METHYLTRANSFERASE KMT5B","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",11,"TYR B 203;SER B 205;GLY B 209;ALA B 210;SER B 251;HIS B 273;TYR B 307;PHE B 312;CYH B 319;GLU B 320;CYH B 321","SAM B 402 (-3.7A);SAM B 402 (-2.7A);SAM B 402 (-3.4A);SAM B 402 (-3.9A);SAM B 402 (-3.9A);SAM B 402 (-4.5A);539 B 403 ( 3.9A);SAM B 402 (-3.7A); ZN B 401 ( 2.3A);SAM B 402 (-4.6A); ZN B 401 ( 2.2A)","0.59A","5wbvB-5cprB:35.5","5wbvB-5cprB:97.80"],["6A5K_A_SAMA805_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.42A","6a5kA-5cprB:8.3","5wbvB-5cprB:97.80"],["6A5M_A_SAMA805_0","HISTONE-LYSINE N-METHYLTRANSFERASE, H3 LYSINE-9 SPECIFIC SUVH6","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.38A","6a5mA-5cprB:undetectable","6a5kA-5cprB:21.76"],["6AGO_A_SAMA2301_0","HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.87A","6agoA-5cprB:7.8","6a5mA-5cprB:21.76"],["6CEN_A_SAMA1301_0","HISTONE-LYSINE N-METHYLTRANSFERASE NSD3","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.53A","6cenA-5cprB:7.4","6agoA-5cprB:26.33"],["6GNG_B_QPSB601_3","-","3fnr","ARGINYL-TRNA SYNTHETASE","Campylobacter jejuni",3,"ASP A 278;ASP A 297;ASN A 114","None;GOL A 539 (-3.4A);None","0.75A","6gngB-3fnrA:3.0","6cenA-5cprB:23.76"],["6INE_A_SAMA2304_0","HISTONE-LYSINE N-METHYLTRANSFERASE ASH1L","5cpr","HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1","Homo sapiens",5,"ASN B 272;HIS B 273;TYR B 307;CYH B 319;CYH B 321","SAM B 402 (-3.1A);SAM B 402 (-4.5A);539 B 403 ( 3.9A); ZN B 401 ( 2.3A); ZN B 401 ( 2.2A)","0.49A","6ineA-5cprB:7.5","6gngB-3fnrA:21.60"]]