SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '520'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.19A 1akdA-4p99A:
undetectable		 1akdA-4p99A:
21.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 7 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.25A 1am6A-5cjfA:
36.3		 1am6A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.18A 1azmA-5cjfA:
35.3		 1azmA-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.18A 1bzmA-5cjfA:
35.1		 1bzmA-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 1cilA-5cjfA:
36.5		 1cilA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.17A 1cilA-5cjfA:
36.5		 1cilA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 HIS A  64
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.22A 1cilA-5cjfA:
36.5		 1cilA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  64
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.14A 1cilA-5cjfA:
36.5		 1cilA-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 4p2f ADENYLATE CYCLASE
(Mycobacterium
tuberculosis) 		5 / 10 ALA A 323
ASP A 325
GLY A 423
ILE A 422
VAL A 392
 None
None
GOL  A 520 (-3.2A)
None
None
 1.13A 1d4yA-4p2fA:
undetectable		 1d4yA-4p2fA:
13.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.46A 1dfoA-2dkjA:
60.5		 1dfoA-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		7 / 12 LEU A 117
GLY A 120
HIS A 122
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.83A 1dfoA-2dkjA:
60.5		 1dfoA-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.47A 1dfoB-2dkjA:
61.9		 1dfoB-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		7 / 12 LEU A 117
GLY A 120
HIS A 122
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.84A 1dfoB-2dkjA:
61.9		 1dfoB-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.46A 1dfoC-2dkjA:
61.9		 1dfoC-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		7 / 12 LEU A 117
GLY A 120
HIS A 122
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.83A 1dfoC-2dkjA:
61.9		 1dfoC-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.47A 1dfoD-2dkjA:
60.5		 1dfoD-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		7 / 12 LEU A 117
GLY A 120
HIS A 122
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.84A 1dfoD-2dkjA:
60.5		 1dfoD-2dkjA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.29A 1dmyA-5cjfA:
33.2		 1dmyA-5cjfA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 1dmyB-5cjfA:
33.1		 1dmyB-5cjfA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.26A 1dmyB-5cjfA:
33.1		 1dmyB-5cjfA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.31A 1dmyB-5cjfA:
33.1		 1dmyB-5cjfA:
33.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.45A 1eqbA-2dkjA:
60.3		 1eqbA-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 12 LEU A 117
GLY A 120
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.83A 1eqbA-2dkjA:
60.3		 1eqbA-2dkjA:
59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A 322
TYR A 191
PHE A 324
 SO4  A 508 (-3.6A)
None
PEG  A 520 (-3.7A)
 0.96A 1eqbB-4qhxA:
undetectable		 1eqbB-4qhxA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 8 SER A  31
HIS A 122
SER A 172
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.49A 1eqbA-2dkjA:
60.3
1eqbB-2dkjA:
61.9		 1eqbA-2dkjA:
59.52
1eqbB-2dkjA:
59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A 322
TYR A 191
PHE A 324
 SO4  A 508 (-3.6A)
None
PEG  A 520 (-3.7A)
 0.96A 1eqbA-4qhxA:
undetectable		 1eqbA-4qhxA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.45A 1eqbB-2dkjA:
61.9		 1eqbB-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 12 LEU A 117
GLY A 120
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.82A 1eqbB-2dkjA:
61.9		 1eqbB-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 8 SER A  31
HIS A 122
SER A 172
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.49A 1eqbA-2dkjA:
60.3
1eqbB-2dkjA:
61.9		 1eqbA-2dkjA:
59.52
1eqbB-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.45A 1eqbC-2dkjA:
61.8		 1eqbC-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 12 LEU A 117
GLY A 120
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.83A 1eqbC-2dkjA:
61.8		 1eqbC-2dkjA:
59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A 322
TYR A 191
PHE A 324
 SO4  A 508 (-3.6A)
None
PEG  A 520 (-3.7A)
 0.97A 1eqbD-4qhxA:
undetectable		 1eqbD-4qhxA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 8 SER A  31
HIS A 122
SER A 172
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.49A 1eqbC-2dkjA:
61.8
1eqbD-2dkjA:
60.6		 1eqbC-2dkjA:
59.52
1eqbD-2dkjA:
59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		3 / 3 GLU A 322
TYR A 191
PHE A 324
 SO4  A 508 (-3.6A)
None
PEG  A 520 (-3.7A)
 0.97A 1eqbC-4qhxA:
undetectable		 1eqbC-4qhxA:
21.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.45A 1eqbD-2dkjA:
60.6		 1eqbD-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 12 LEU A 117
GLY A 120
SER A 172
ALA A 173
ASN A 342
ARG A 358
 None
None
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.83A 1eqbD-2dkjA:
60.6		 1eqbD-2dkjA:
59.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 8 SER A  31
HIS A 122
SER A 172
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.50A 1eqbC-2dkjA:
61.8
1eqbD-2dkjA:
60.6		 1eqbC-2dkjA:
59.52
1eqbD-2dkjA:
59.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Legionella
pneumophila) 		5 / 12 PRO A 415
GLY A 192
SER A 166
ASP A 129
MET A 452
 GOL  A 520 ( 4.8A)
ZN  A 504 ( 3.9A)
None
ZN  A 502 ( 2.3A)
None
 1.08A 1ffyA-3pfeA:
undetectable		 1ffyA-3pfeA:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.87A 1jd0A-5cjfA:
41.5		 1jd0A-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.43A 1jd0A-5cjfA:
41.5		 1jd0A-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.45A 1jd0A-5cjfA:
41.5		 1jd0A-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 1jd0A-5cjfA:
41.5		 1jd0A-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.84A 1jd0B-5cjfA:
41.5		 1jd0B-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
 1.02A 1jd0B-5cjfA:
41.5		 1jd0B-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.41A 1jd0B-5cjfA:
41.5		 1jd0B-5cjfA:
46.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.92A 1jd0B-5cjfA:
41.5		 1jd0B-5cjfA:
46.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_1
(DNA GYRASE SUBUNIT B)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 ASP A 109
ARG A 158
ILE A 161
ILE A 187
ARG A 162
 None
FMN  A5201 (-3.7A)
FMN  A5201 (-3.8A)
FMN  A5201 (-4.0A)
SO4  A5202 ( 2.4A)
 1.36A 1kijA-4wujA:
undetectable		 1kijA-4wujA:
18.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 ASN A  62
HIS A  96
LEU A 198
THR A 199
PRO A 202
 GOL  A 303 (-3.9A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.96A 1oq5A-5cjfA:
36.9		 1oq5A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
PRO A 202
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 0.39A 1oq5A-5cjfA:
36.9		 1oq5A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.50A 1oq5A-5cjfA:
36.9		 1oq5A-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PHG_A_MYTA422_1
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 11 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.17A 1phgA-4p99A:
undetectable		 1phgA-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_E_RTLE1_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Legionella
pneumophila) 		5 / 11 LEU A  78
VAL A  70
MET A 419
LEU A 175
TYR A  94
 None
None
GOL  A 520 ( 3.8A)
None
None
 1.49A 1qabE-3pfeA:
undetectable		 1qabE-3pfeA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3pfe SUCCINYL-DIAMINOPIME
LATE DESUCCINYLASE
(Legionella
pneumophila) 		5 / 12 PRO A 415
GLY A 192
SER A 166
ASP A 129
MET A 452
 GOL  A 520 ( 4.8A)
ZN  A 504 ( 3.9A)
None
ZN  A 502 ( 2.3A)
None
 1.08A 1qu2A-3pfeA:
undetectable		 1qu2A-3pfeA:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.01A 1rj6A-5cjfA:
43.0		 1rj6A-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.42A 1rj6A-5cjfA:
43.0		 1rj6A-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 10 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 131
LEU A 198
THR A 199
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.44A 1rj6A-5cjfA:
43.0		 1rj6A-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.86A 1rj6A-5cjfA:
43.0		 1rj6A-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.00A 1rj6B-5cjfA:
42.8		 1rj6B-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.37A 1rj6B-5cjfA:
42.8		 1rj6B-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.86A 1rj6B-5cjfA:
42.8		 1rj6B-5cjfA:
82.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.34A 1ydaA-5cjfA:
36.0		 1ydaA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.21A 1ydbA-5cjfA:
36.2		 1ydbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
THR A 199
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.27A 1yddA-5cjfA:
36.4		 1yddA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 1z9yA-5cjfA:
36.4		 1z9yA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.11A 1z9yA-5cjfA:
36.4		 1z9yA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.24A 1z9yA-5cjfA:
36.4		 1z9yA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 1z9yA-5cjfA:
36.4		 1z9yA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.30A 1zgfA-5cjfA:
36.6		 1zgfA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 1zgfA-5cjfA:
36.6		 1zgfA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.24A 1zgfA-5cjfA:
36.6		 1zgfA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.34A 1zgfA-5cjfA:
36.6		 1zgfA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.47A 1zgfA-5cjfA:
36.6		 1zgfA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZLQ_A_EDTA1513_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		9 / 9 TYR A  22
MET A  27
ARG A  97
TRP A 100
ARG A 137
TRP A 398
TYR A 402
HIS A 416
THR A 490
 BHR  A 520 (-4.2A)
BHR  A 520 (-3.7A)
BHR  A 520 ( 2.9A)
BHR  A 520 (-3.5A)
BHR  A 520 (-3.8A)
BHR  A 520 (-3.8A)
BHR  A 520 ( 4.6A)
None
BHR  A 520 (-4.4A)
 0.40A 1zlqA-3mzbA:
61.6		 1zlqA-3mzbA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZLQ_B_EDTB1511_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		8 / 8 TYR A  22
MET A  27
ARG A  97
TRP A 100
ARG A 137
TRP A 398
TYR A 402
THR A 490
 BHR  A 520 (-4.2A)
BHR  A 520 (-3.7A)
BHR  A 520 ( 2.9A)
BHR  A 520 (-3.5A)
BHR  A 520 (-3.8A)
BHR  A 520 (-3.8A)
BHR  A 520 ( 4.6A)
BHR  A 520 (-4.4A)
 0.30A 1zlqB-3mzbA:
59.7		 1zlqB-3mzbA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.88A 1zsbA-5cjfA:
36.9		 1zsbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.15A 1zsbA-5cjfA:
36.9		 1zsbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.49A 1zsbA-5cjfA:
36.9		 1zsbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.31A 1zsbA-5cjfA:
36.9		 1zsbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.94A 1zsbA-5cjfA:
36.9		 1zsbA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.11A 2aw1A-5cjfA:
36.4		 2aw1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.26A 2aw1A-5cjfA:
36.4		 2aw1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 143
LEU A 141
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.29A 2aw1A-5cjfA:
36.4		 2aw1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 4mzy NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE
(Enterococcus
faecalis) 		4 / 6 ARG A 163
SER A 187
GLY A 201
ARG A 262
 CL  A 518 (-4.1A)
None
CL  A 521 (-3.8A)
FMT  A 520 (-3.1A)
 0.65A 2f7fA-4mzyA:
59.0		 2f7fA-4mzyA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.41A 2gehA-5cjfA:
36.7		 2gehA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.88A 2h4nA-5cjfA:
37.0		 2h4nA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 9 GLN A  92
HIS A  96
HIS A 119
VAL A 121
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.45A 2h4nA-5cjfA:
37.0		 2h4nA-5cjfA:
36.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.27A 2it4A-5cjfA:
35.7		 2it4A-5cjfA:
35.11
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 8 HIS A  96
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.81A 2it4A-5cjfA:
35.7		 2it4A-5cjfA:
35.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KUH_A_HLTA150_1
(CALMODULIN)		 5svd NUCLEOLAR PROTEIN 9
(Saccharomyces
cerevisiae) 		4 / 6 LEU A 517
MET A 509
LEU A 461
MET A 520
 LEU  A 517 ( 0.5A)
MET  A 509 ( 0.0A)
LEU  A 461 ( 0.6A)
MET  A 520 ( 0.0A)
 1.11A 2kuhA-5svdA:
undetectable		 2kuhA-5svdA:
8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 4p2f ADENYLATE CYCLASE
(Mycobacterium
tuberculosis) 		5 / 11 ALA A 323
ASP A 325
GLY A 423
ILE A 422
VAL A 392
 None
None
GOL  A 520 (-3.2A)
None
None
 1.11A 2o4pA-4p2fA:
undetectable		 2o4pA-4p2fA:
14.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 ASN A  62
GLN A  67
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.21A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
 1.16A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 ASN A  62
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.9A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.9A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 0.84A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.23A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 2pouA-5cjfA:
36.7		 2pouA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		8 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
SO4  A2520 (-2.9A)
 0.47A 2vmyB-2dkjA:
60.4		 2vmyB-2dkjA:
66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VMY_A_GLYA502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		5 / 7 SER A  31
HIS A 122
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.50A 2vmyA-2dkjA:
61.7
2vmyB-2dkjA:
60.4		 2vmyA-2dkjA:
66.01
2vmyB-2dkjA:
66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VMY_B_FFOB505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		9 / 12 LEU A 117
GLY A 120
HIS A 122
LEU A 123
VAL A 129
SER A 172
ALA A 173
ASN A 340
ARG A 358
 None
None
PLP  A 510 (-3.5A)
None
None
PLP  A 510 ( 3.2A)
None
None
SO4  A2520 (-2.9A)
 0.57A 2vmyA-2dkjA:
61.7		 2vmyA-2dkjA:
66.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VMY_B_GLYB502_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		6 / 8 SER A  31
HIS A 122
SER A 172
HIS A 200
LYS A 226
ARG A 358
 SO4  A2520 (-2.7A)
PLP  A 510 (-3.5A)
PLP  A 510 ( 3.2A)
SO4  A2520 ( 4.0A)
PLP  A 510 ( 1.3A)
SO4  A2520 (-2.9A)
 0.49A 2vmyA-2dkjA:
61.7
2vmyB-2dkjA:
60.4		 2vmyA-2dkjA:
66.01
2vmyB-2dkjA:
66.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1161_1
(ALLERGEN ARG R 1)		 5gpr CHITINASE
(Ostrinia
furnacalis) 		4 / 4 VAL A 521
TYR A 520
VAL A 417
SER A 382
 VAL  A 521 ( 0.6A)
TYR  A 520 ( 1.3A)
VAL  A 417 ( 0.6A)
SER  A 382 ( 0.0A)
 1.17A 2x45B-5gprA:
undetectable		 2x45B-5gprA:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 6an0 HISTIDINOL
DEHYDROGENASE
(Elizabethkingia
anophelis) 		4 / 5 ARG A 116
ALA A 115
GLU A 114
TRP A 112
 None
HIS  A 520 (-3.5A)
HIS  A 520 (-4.4A)
None
 1.50A 2xrzA-6an0A:
2.7		 2xrzA-6an0A:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		4 / 7 ILE A  81
LEU A  78
THR A 101
LEU A 100
 None
None
FMN  A5201 (-3.4A)
None
 0.98A 3ablA-4wujA:
undetectable
3ablJ-4wujA:
undetectable		 3ablA-4wujA:
16.16
3ablJ-4wujA:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.27A 3bl1A-5cjfA:
36.5		 3bl1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 3bl1A-5cjfA:
36.5		 3bl1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
VAL A 121
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.02A 3bl1A-5cjfA:
36.5		 3bl1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.89A 3bl1A-5cjfA:
36.5		 3bl1A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.39A 3cajA-5cjfA:
36.6		 3cajA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A 119
THR A 199
PRO A 201
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
None
None
 1.29A 3cajA-5cjfA:
36.6		 3cajA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.90A 3cajA-5cjfA:
36.6		 3cajA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
 0.89A 3czvA-5cjfA:
36.5
3czvB-5cjfA:
36.1		 3czvA-5cjfA:
37.78
3czvB-5cjfA:
37.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.52A 3czvA-5cjfA:
36.5
3czvB-5cjfA:
36.1		 3czvA-5cjfA:
37.78
3czvB-5cjfA:
37.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
 0.97A 3czvB-5cjfA:
36.1		 3czvB-5cjfA:
37.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.47A 3czvB-5cjfA:
36.1		 3czvB-5cjfA:
37.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.00A 3dazA-5cjfA:
36.9		 3dazA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.28A 3dazA-5cjfA:
36.9		 3dazA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.93A 3dazA-5cjfA:
36.9		 3dazA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 200
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.44A 3dazA-5cjfA:
36.9		 3dazA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.89A 3dc3A-5cjfA:
36.9		 3dc3A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.13A 3dc3A-5cjfA:
36.9		 3dc3A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.30A 3dc3A-5cjfA:
36.9		 3dc3A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.92A 3dcsA-5cjfA:
36.9		 3dcsA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.36A 3dcsA-5cjfA:
36.9		 3dcsA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.94A 3dcsA-5cjfA:
36.9		 3dcsA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.33A 3dcwA-5cjfA:
37.0		 3dcwA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 HIS A  94
HIS A 119
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 1.44A 3dcwA-5cjfA:
37.0		 3dcwA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.81A 3dcwA-5cjfA:
37.0		 3dcwA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 3dcwA-5cjfA:
37.0		 3dcwA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.35A 3dd0A-5cjfA:
36.8		 3dd0A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.83A 3dd0A-5cjfA:
36.8		 3dd0A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 3dd0A-5cjfA:
36.8		 3dd0A-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ALA A 326
THR A 330
CYH A 462
 HEM  A 520 ( 3.3A)
HEM  A 520 ( 3.8A)
HEM  A 520 ( 2.2A)
 0.55A 3e4eA-3k9yA:
33.6		 3e4eA-3k9yA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL
(Rattus
norvegicus) 		3 / 3 ALA A 326
THR A 330
CYH A 462
 HEM  A 520 ( 3.3A)
HEM  A 520 ( 3.8A)
HEM  A 520 ( 2.2A)
 0.47A 3e4eB-3k9yA:
32.5		 3e4eB-3k9yA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 9 ARG B 109
VAL B 145
GLY B 180
ILE B  74
ILE B 135
 FAD  B5201 (-4.3A)
None
FAD  B5201 (-3.8A)
FAD  B5201 (-4.9A)
FAD  B5201 ( 4.4A)
 1.13A 3ekqB-3rh8B:
undetectable		 3ekqB-3rh8B:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 ILE B 119
ASN B  53
THR B  22
VAL B  76
ILE B  79
 None
FMN  B5201 (-2.9A)
FMN  B5201 (-2.5A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 3.1A)
 1.37A 3em0B-5svwB:
undetectable		 3em0B-5svwB:
20.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.41A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  94
LEU A 198
THR A 199
PRO A 201
TRP A 209
 GOL  A 303 (-3.9A)
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 1.45A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  96
LEU A 198
THR A 199
THR A 200
PRO A 202
 GOL  A 303 (-3.9A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.93A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  96
VAL A 121
LEU A 198
THR A 200
PRO A 202
 GOL  A 303 (-3.9A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.88A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.50A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 3f4xA-5cjfA:
36.2		 3f4xA-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 2vbf BRANCHED-CHAIN
ALPHA-KETOACID
DECARBOXYLASE
(Lactococcus
lactis) 		5 / 9 ILE A 450
TYR A 520
ILE A 522
LYS A 497
GLU A 511
 ILE  A 450 ( 0.7A)
TYR  A 520 ( 1.3A)
ILE  A 522 ( 0.6A)
LYS  A 497 ( 0.0A)
GLU  A 511 ( 0.6A)
 1.04A 3f78A-2vbfA:
3.8		 3f78A-2vbfA:
16.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
None
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.49A 3fw3A-5cjfA:
34.2		 3fw3A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  64
GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 None
GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.93A 3fw3A-5cjfA:
34.2		 3fw3A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 3fw3A-5cjfA:
34.2		 3fw3A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.35A 3fw3B-5cjfA:
33.9		 3fw3B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 3fw3B-5cjfA:
33.9		 3fw3B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 ASN A  62
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.24A 3hkuA-5cjfA:
36.9		 3hkuA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.26A 3hkuA-5cjfA:
36.9		 3hkuA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.11A 3hkuA-5cjfA:
36.9		 3hkuA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		3 / 3 GLU A 106
HIS A 119
THR A 199
 ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
 0.10A 3hkuA-5cjfA:
36.9		 3hkuA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 3hs4A-5cjfA:
37.2		 3hs4A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.16A 3hs4A-5cjfA:
37.2		 3hs4A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.19A 3hs4A-5cjfA:
37.2		 3hs4A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.48A 3hs4A-5cjfA:
37.2		 3hs4A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.90A 3hs4A-5cjfA:
37.2		 3hs4A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 3iaiA-5cjfA:
37.6		 3iaiA-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.30A 3iaiA-5cjfA:
37.6		 3iaiA-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 3iaiA-5cjfA:
37.6		 3iaiA-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 3iaiB-5cjfA:
38.0		 3iaiB-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.29A 3iaiB-5cjfA:
38.0		 3iaiB-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 3iaiB-5cjfA:
38.0		 3iaiB-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 3iaiC-5cjfA:
38.0		 3iaiC-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.28A 3iaiC-5cjfA:
38.0		 3iaiC-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 3iaiC-5cjfA:
38.0		 3iaiC-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 3iaiD-5cjfA:
38.0		 3iaiD-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.27A 3iaiD-5cjfA:
38.0		 3iaiD-5cjfA:
41.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 3iaiD-5cjfA:
38.0		 3iaiD-5cjfA:
41.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN
(Zobellia
galactanivorans) 		5 / 9 TYR A  70
GLY A 351
ALA A 331
THR A 287
ILE A 300
 EDO  A 520 (-4.3A)
None
None
None
None
 1.40A 3jusB-4u6dA:
undetectable		 3jusB-4u6dA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3rrk V-TYPE ATPASE 116
KDA SUBUNIT
(Meiothermus
ruber) 		3 / 3 ALA A 160
ARG A 162
LYS A 181
 None
None
NHE  A 520 (-3.2A)
 0.77A 3kp3B-3rrkA:
undetectable		 3kp3B-3rrkA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 3zmr CELLULASE (GLYCOSYL
HYDROLASE FAMILY 5)
(Bacteroides
ovatus) 		3 / 3 ASN A 162
ASN A 165
GLU A 478
 None
BGC  A1520 (-3.2A)
None
 0.82A 3kpdC-3zmrA:
undetectable		 3kpdC-3zmrA:
13.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.40A 3kwaA-5cjfA:
36.3		 3kwaA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 1.38A 3kwaA-5cjfA:
36.3		 3kwaA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 1.20A 3kwaA-5cjfA:
36.3		 3kwaA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.49A 3kwaA-5cjfA:
36.3		 3kwaA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.50A 3lxeA-5cjfA:
35.9		 3lxeA-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.49A 3lxeB-5cjfA:
35.9		 3lxeB-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
ALA A 135
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 3.7A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.38A 3mdzA-5cjfA:
36.6		 3mdzA-5cjfA:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.92A 3mdzA-5cjfA:
36.6		 3mdzA-5cjfA:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.28A 3ml5A-5cjfA:
36.8		 3ml5A-5cjfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.29A 3ml5A-5cjfA:
36.8		 3ml5A-5cjfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.36A 3ml5A-5cjfA:
36.8		 3ml5A-5cjfA:
37.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.98A 3ml5A-5cjfA:
36.8		 3ml5A-5cjfA:
37.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_A_NPSA5_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.93A 3nt1A-4wujA:
undetectable		 3nt1A-4wujA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NT1_B_NPSB4_1
(PROSTAGLANDIN-ENDOPE
ROXIDE SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.93A 3nt1B-4wujA:
undetectable		 3nt1B-4wujA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_C_FLRC700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.82A 3rr3C-4wujA:
undetectable		 3rr3C-4wujA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RR3_D_FLRD700_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.83A 3rr3D-4wujA:
undetectable		 3rr3D-4wujA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_1
(HIV-1 PROTEASE)		 2dkj SERINE
HYDROXYMETHYLTRANSFE
RASE
(Thermus
thermophilus) 		5 / 9 ARG A 358
LEU A 313
ASN A 311
VAL A 286
GLY A 203
 SO4  A2520 (-2.9A)
None
None
None
None
 1.24A 3spkA-2dkjA:
undetectable		 3spkA-2dkjA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 12 ARG A 157
GLY A 158
LEU A 369
SER A 392
GLU A 322
 PEG  A 520 ( 4.4A)
None
None
SO4  A 503 ( 4.4A)
SO4  A 508 (-3.6A)
 1.22A 3sxjA-4qhxA:
undetectable		 3sxjA-4qhxA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		5 / 12 ARG A 157
GLY A 158
LEU A 369
SER A 392
GLU A 322
 PEG  A 520 ( 4.4A)
None
None
SO4  A 503 ( 4.4A)
SO4  A 508 (-3.6A)
 1.22A 3sxjB-4qhxA:
undetectable		 3sxjB-4qhxA:
20.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.18A 3v2jA-5cjfA:
36.9		 3v2jA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.21A 3v2jA-5cjfA:
36.9		 3v2jA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.31A 3v2jA-5cjfA:
36.9		 3v2jA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.34A 3v2jA-5cjfA:
36.9		 3v2jA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.03A 3v2mA-5cjfA:
37.1		 3v2mA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.21A 3v2mA-5cjfA:
37.1		 3v2mA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.47A 3v2mA-5cjfA:
37.1		 3v2mA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.93A 3v2mA-5cjfA:
37.1		 3v2mA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 8 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
 0.86A 3w6hA-5cjfA:
35.7		 3w6hA-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.39A 3w6hA-5cjfA:
35.7		 3w6hA-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 9 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
 0.79A 3w6hB-5cjfA:
35.6		 3w6hB-5cjfA:
34.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
LEU A 198
THR A 199
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.40A 3w6hB-5cjfA:
35.6		 3w6hB-5cjfA:
34.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)		 4apm APICAL MEMBRANE
ANTIGEN 1
(Babesia
divergens) 		6 / 12 LEU A 167
MET A 278
GLY A 148
THR A 272
LEU A 147
GLY A 166
 None
None
None
None
GOL  A1520 (-4.5A)
None
 1.37A 3zbfA-4apmA:
undetectable		 3zbfA-4apmA:
20.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.93A 3zncA-5cjfA:
33.5		 3zncA-5cjfA:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.44A 3zncA-5cjfA:
33.5		 3zncA-5cjfA:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 3zncA-5cjfA:
33.5		 3zncA-5cjfA:
37.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.47A 3zncA-5cjfA:
33.5		 3zncA-5cjfA:
37.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 7 LEU A 198
GLU A 117
HIS A 119
HIS A  94
 520  A 302 (-3.6A)
None
ZN  A 301 ( 3.1A)
ZN  A 301 (-3.2A)
 1.23A 4aq7A-5cjfA:
undetectable		 4aq7A-5cjfA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.08A 4b7nA-6az1D:
undetectable		 4b7nA-6az1D:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.12A 4c9nB-4p99A:
undetectable		 4c9nB-4p99A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		5 / 10 THR A 264
GLY A 240
VAL A 291
ASP A 251
VAL A 253
 None
None
None
CA  A 520 ( 4.7A)
None
 1.19A 4c9pB-4p99A:
undetectable		 4c9pB-4p99A:
23.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.01A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.18A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.25A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.24A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.36A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.98A 4coqA-5cjfA:
30.0		 4coqA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.27A 4coqB-5cjfA:
30.1		 4coqB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.24A 4coqB-5cjfA:
30.1		 4coqB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.40A 4coqB-5cjfA:
30.1		 4coqB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.33A 4coqB-5cjfA:
30.1		 4coqB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.00A 4coqB-5cjfA:
30.1		 4coqB-5cjfA:
30.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 4p99 MPAFP_RII
TETRA-TANDEMER
(Marinomonas
primoryensis) 		4 / 7 THR A 264
VAL A 291
ASP A 251
VAL A 253
 None
None
CA  A 520 ( 4.7A)
None
 0.91A 4cp4A-4p99A:
undetectable		 4cp4A-4p99A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.13A 4cpzC-6az1D:
undetectable		 4cpzC-6az1D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.14A 4cpzE-6az1D:
undetectable		 4cpzE-6az1D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.10A 4cpzF-6az1D:
undetectable		 4cpzF-6az1D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.10A 4cpzG-6az1D:
undetectable		 4cpzG-6az1D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 6az1 RIBOSOMAL PROTEIN S4
(Leishmania
donovani) 		3 / 3 ARG D  39
ARG D  43
TRP D  11
 A  1 643 ( 3.2A)
A  1 521 ( 3.7A)
G  1 520 ( 4.4A)
 1.10A 4cpzH-6az1D:
undetectable		 4cpzH-6az1D:
11.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2pvq GLUTATHIONE
S-TRANSFERASE
(Ochrobactrum
anthropi) 		4 / 4 GLY A   8
TRP A 164
VAL A 160
SER A  11
 GSH  A5204 (-3.5A)
GSH  A5204 (-4.0A)
None
None
 1.49A 4d39A-2pvqA:
0.2		 4d39A-2pvqA:
18.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 GLN A  92
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
VAL A 207
TRP A 209
 GOL  A 303 (-3.2A)
520  A 302 ( 4.9A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.27A 4e3hA-5cjfA:
36.6		 4e3hA-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 4 PRO A 112
LEU A 115
ILE A 457
ARG A 396
 None
None
None
HEM  A 520 ( 2.8A)
 1.44A 4f4dA-3k9yA:
undetectable		 4f4dA-3k9yA:
22.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.92A 4g0cA-5cjfA:
36.8		 4g0cA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
THR A 199
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
 1.22A 4g0cA-5cjfA:
36.8		 4g0cA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.22A 4g0cA-5cjfA:
36.8		 4g0cA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 4g0cA-5cjfA:
36.8		 4g0cA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 4g7aA-5cjfA:
29.9		 4g7aA-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.11A 4g7aA-5cjfA:
29.9		 4g7aA-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.47A 4g7aA-5cjfA:
29.9		 4g7aA-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.22A 4g7aA-5cjfA:
29.9		 4g7aA-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.99A 4g7aA-5cjfA:
29.9		 4g7aA-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.96A 4g7aB-5cjfA:
29.6		 4g7aB-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.15A 4g7aB-5cjfA:
29.6		 4g7aB-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.49A 4g7aB-5cjfA:
29.6		 4g7aB-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.26A 4g7aB-5cjfA:
29.6		 4g7aB-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.99A 4g7aB-5cjfA:
29.6		 4g7aB-5cjfA:
30.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
LEU A 131
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.8A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.25A 4k0sA-5cjfA:
36.9		 4k0sA-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.24A 4k0sA-5cjfA:
36.9		 4k0sA-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.62A 4k0sA-5cjfA:
36.9		 4k0sA-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.28A 4k0sA-5cjfA:
36.9		 4k0sA-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
VAL A 143
LEU A 131
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.39A 4k0sA-5cjfA:
36.9		 4k0sA-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.46A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.48A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A  94
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.47A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 1.37A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 HIS A  96
HIS A 119
LEU A 131
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.8A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.82A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 143
LEU A 131
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.38A 4k0zA-5cjfA:
36.7		 4k0zA-5cjfA:
37.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 131
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.48A 4k13A-5cjfA:
37.0		 4k13A-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 141
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.38A 4k13A-5cjfA:
37.0		 4k13A-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.46A 4k13A-5cjfA:
37.0		 4k13A-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 143
LEU A 141
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.31A 4k13A-5cjfA:
37.0		 4k13A-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A 107
VAL A 143
LEU A 141
LEU A 198
THR A 199
 ZN  A 301 ( 3.1A)
None
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.48A 4k13A-5cjfA:
37.0		 4k13A-5cjfA:
38.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 109
GLN B 112
ASN B 151
ASN B 161
ILE B  74
 FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-4.9A)
 1.37A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
ILE B 165
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 ( 4.1A)
FAD  B5201 (-4.1A)
 1.37A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ASN B 151
ASN B 161
LEU B 163
ILE B 165
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 ( 4.1A)
FAD  B5201 (-4.1A)
 0.57A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 SER B 178
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.93A 4kukA-3rh8B:
17.5		 4kukA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 ASN A 134
CYH A 135
ARG A 136
GLN A 139
ASN A 173
ASN A 183
ILE A 187
GLN A 204
 FMN  A5201 (-2.5A)
FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-4.0A)
FMN  A5201 (-3.7A)
 0.65A 4kukA-4wujA:
16.5		 4kukA-4wujA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 ARG B  55
GLN B  58
ASN B  95
ASN B 105
ILE B  20
 FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 (-2.9A)
 1.42A 4kukA-5svwB:
16.5		 4kukA-5svwB:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 ASN B  53
CYH B  54
ARG B  55
GLN B  58
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.86A 4kukA-5svwB:
16.5		 4kukA-5svwB:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUK_A_RBFA201_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		5 / 12 ASN B  53
CYH B  54
ARG B  55
LEU B 109
ILE B 122
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-4.0A)
FMN  B5201 (-3.1A)
 0.98A 4kukA-5svwB:
16.5		 4kukA-5svwB:
33.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.32A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.59A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		6 / 12 SER B 178
GLN B 112
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.06A 4kuoA-3rh8B:
17.1		 4kuoA-3rh8B:
32.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		7 / 12 ASN A 134
CYH A 135
ARG A 136
GLN A 139
ASN A 173
ASN A 183
GLN A 204
 FMN  A5201 (-2.5A)
FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.7A)
 0.71A 4kuoA-4wujA:
16.2		 4kuoA-4wujA:
35.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KUO_A_RBFA500_1
(BLUE-LIGHT
PHOTORECEPTOR)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 ASN B  53
CYH B  54
ARG B  55
GLN B  58
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.91A 4kuoA-5svwB:
16.8		 4kuoA-5svwB:
33.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1qdb CYTOCHROME C NITRITE
REDUCTASE
(Sulfurospirillum
deleyianum) 		4 / 8 ASP A 267
GLN A 281
VAL A 237
THR A 238
 CA  A 520 ( 4.3A)
CA  A 520 ( 3.2A)
HEM  A 515 ( 4.7A)
None
 1.15A 4lnwA-1qdbA:
undetectable		 4lnwA-1qdbA:
20.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 4lu3A-5cjfA:
48.5		 4lu3A-5cjfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  92
GLU A 117
VAL A 121
LEU A 131
THR A 199
 GOL  A 303 (-3.2A)
None
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.4A)
 1.14A 4lu3A-5cjfA:
48.5		 4lu3A-5cjfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 131
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.8A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.10A 4lu3A-5cjfA:
48.5		 4lu3A-5cjfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.50A 4lu3A-5cjfA:
48.5		 4lu3A-5cjfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.89A 4lu3A-5cjfA:
48.5		 4lu3A-5cjfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.35A 4m2rA-5cjfA:
36.9		 4m2rA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 ASN A  62
HIS A  94
LEU A 198
THR A 199
PRO A 201
TRP A 209
 GOL  A 303 (-3.9A)
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 1.47A 4m2rA-5cjfA:
36.9		 4m2rA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.18A 4m2rA-5cjfA:
36.9		 4m2rA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.88A 4m2rA-5cjfA:
36.9		 4m2rA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.14A 4m2uA-5cjfA:
36.9		 4m2uA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 TRP A   5
GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.35A 4m2uA-5cjfA:
36.9		 4m2uA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 TRP A   5
HIS A  64
GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.29A 4m2uA-5cjfA:
36.9		 4m2uA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 TRP A   5
HIS A  64
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 None
None
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.22A 4m2uA-5cjfA:
36.9		 4m2uA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.36A 4m2uA-5cjfA:
36.9		 4m2uA-5cjfA:
37.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.15A 4m2vA-5cjfA:
36.9		 4m2vA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.20A 4m2vA-5cjfA:
36.9		 4m2vA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 LEU A 131
HIS A  94
HIS A  96
VAL A 143
THR A 200
TRP A 209
 520  A 302 ( 4.8A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
None
 1.00A 4m2vA-5cjfA:
36.9		 4m2vA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.98A 4m2wA-5cjfA:
36.9		 4m2wA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.18A 4m2wA-5cjfA:
36.9		 4m2wA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
VAL A 143
LEU A 141
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.25A 4m2wA-5cjfA:
36.9		 4m2wA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 LEU A 131
HIS A  94
HIS A  96
VAL A 143
THR A 199
THR A 200
TRP A 209
 520  A 302 ( 4.8A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.95A 4m2wA-5cjfA:
36.9		 4m2wA-5cjfA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 8 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 4n16A-5cjfA:
36.9		 4n16A-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 8 GLN A  92
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.23A 4n16A-5cjfA:
36.9		 4n16A-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3ed4 ARYLSULFATASE
(Escherichia
coli) 		4 / 5 ASN A 170
ALA A 172
GLY A 173
ASP A 273
 None
None
SO4  A 520 (-3.7A)
None
 0.98A 4n48A-3ed4A:
undetectable		 4n48A-3ed4A:
23.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OES_A_EDTA601_0
(NIKA PROTEIN)		 3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		6 / 6 TYR A  22
MET A  27
TRP A 100
ARG A 137
TRP A 398
TYR A 402
 BHR  A 520 (-4.2A)
BHR  A 520 (-3.7A)
BHR  A 520 (-3.5A)
BHR  A 520 (-3.8A)
BHR  A 520 (-3.8A)
BHR  A 520 ( 4.6A)
 0.34A 4oesA-3mzbA:
54.5		 4oesA-3mzbA:
64.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 4pxxA-5cjfA:
37.2		 4pxxA-5cjfA:
37.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.26A 4pxxA-5cjfA:
37.2		 4pxxA-5cjfA:
37.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		3 / 3 PHE B 128
THR B  22
LEU B  57
 None
FMN  B5201 (-2.5A)
FMN  B5201 (-3.7A)
 0.74A 4qztA-5svwB:
undetectable		 4qztA-5svwB:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 1qdb CYTOCHROME C NITRITE
REDUCTASE
(Sulfurospirillum
deleyianum) 		4 / 5 TYR A  89
TYR A 260
GLU A 216
GLN A 281
 None
None
CA  A 520 (-2.4A)
CA  A 520 ( 3.2A)
 1.25A 4qztB-1qdbA:
0.0		 4qztB-1qdbA:
13.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.11A 4r38A-3rh8B:
16.3		 4r38A-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.70A 4r38A-3rh8B:
16.3		 4r38A-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 CYH A 135
ARG A 136
GLN A 139
ILE A 161
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.8A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 0.77A 4r38A-4wujA:
15.4		 4r38A-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.96A 4r38A-5svwB:
17.4		 4r38A-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLY B 124
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.0A)
 0.70A 4r38A-5svwB:
17.4		 4r38A-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 8 THR A 101
ASN A 134
LEU A 138
VAL A 154
ILE A 171
 FMN  A5201 (-3.4A)
FMN  A5201 (-2.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.6A)
FMN  A5201 ( 4.4A)
 0.57A 4r38A-4wujA:
15.4		 4r38A-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 8 THR A 101
ILE A 105
ASN A 134
LEU A 138
VAL A 154
 FMN  A5201 (-3.4A)
None
FMN  A5201 (-2.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.6A)
 0.67A 4r38A-4wujA:
15.4		 4r38A-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.13A 4r38B-3rh8B:
16.4		 4r38B-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		10 / 12 ASN B 107
CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-3.2A)
FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.68A 4r38B-3rh8B:
16.4		 4r38B-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		9 / 12 ASN A 134
CYH A 135
ARG A 136
GLN A 139
ILE A 161
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-2.5A)
FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.8A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 0.78A 4r38B-4wujA:
15.5		 4r38B-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		9 / 12 ASN B  53
CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.98A 4r38B-5svwB:
17.3		 4r38B-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_B_RBFB201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		9 / 12 ASN B  53
CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLY B 124
 FMN  B5201 (-2.9A)
FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.0A)
 0.71A 4r38B-5svwB:
17.3		 4r38B-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.11A 4r38C-3rh8B:
16.4		 4r38C-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.67A 4r38C-3rh8B:
16.4		 4r38C-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 CYH A 135
ARG A 136
GLN A 139
ILE A 161
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.8A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 0.75A 4r38C-4wujA:
15.4		 4r38C-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.95A 4r38C-5svwB:
17.5		 4r38C-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLY B 124
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.0A)
 0.66A 4r38C-5svwB:
17.5		 4r38C-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		6 / 9 THR A 101
ILE A 105
ASN A 134
LEU A 138
VAL A 154
ILE A 171
 FMN  A5201 (-3.4A)
None
FMN  A5201 (-2.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.6A)
FMN  A5201 ( 4.4A)
 0.78A 4r38C-4wujA:
15.4		 4r38C-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.10A 4r38D-3rh8B:
16.5		 4r38D-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		9 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.67A 4r38D-3rh8B:
16.5		 4r38D-3rh8B:
31.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 CYH A 135
ARG A 136
GLN A 139
ILE A 161
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.8A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 0.78A 4r38D-4wujA:
15.5		 4r38D-4wujA:
33.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.98A 4r38D-5svwB:
17.4		 4r38D-5svwB:
32.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLY B 124
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.0A)
 0.70A 4r38D-5svwB:
17.4		 4r38D-5svwB:
32.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		5 / 12 ARG B 124
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-3.4A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 1.21A 4r3aA-3rh8B:
12.7		 4r3aA-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 CYH B 108
ARG B 109
GLN B 112
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-3.1A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.63A 4r3aA-3rh8B:
12.7		 4r3aA-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		6 / 12 ALA A 200
ILE A 161
ILE A 171
ASN A 173
ASN A 183
GLN A 204
 FMN  A5201 (-2.8A)
FMN  A5201 (-3.8A)
FMN  A5201 ( 4.4A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.7A)
 1.23A 4r3aA-4wujA:
12.0		 4r3aA-4wujA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 CYH A 135
ARG A 136
GLN A 139
ILE A 161
ILE A 171
ASN A 173
ASN A 183
GLN A 204
 FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.8A)
FMN  A5201 ( 4.4A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.7A)
 0.70A 4r3aA-4wujA:
12.0		 4r3aA-4wujA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		8 / 12 CYH B  54
ARG B  55
GLN B  58
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-3.1A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.98A 4r3aA-5svwB:
15.0		 4r3aA-5svwB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		6 / 10 THR A 101
ILE A 105
ASN A 134
LEU A 138
GLN A 139
VAL A 154
 FMN  A5201 (-3.4A)
None
FMN  A5201 (-2.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.1A)
FMN  A5201 (-3.6A)
 0.65A 4r3aB-4wujA:
12.2		 4r3aB-4wujA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		5 / 10 ILE B 122
ASN B  53
LEU B  57
GLN B  58
VAL B  76
 FMN  B5201 (-3.1A)
FMN  B5201 (-2.9A)
FMN  B5201 (-3.7A)
FMN  B5201 (-3.1A)
FMN  B5201 (-3.8A)
 1.00A 4r3aB-5svwB:
13.9		 4r3aB-5svwB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3rh8 VIVID PAS PROTEIN
VVD
(Neurospora
crassa) 		8 / 12 CYH B 108
ARG B 109
ILE B 139
ASN B 151
ASN B 161
LEU B 163
GLY B 180
GLN B 182
 FAD  B5201 (-1.8A)
FAD  B5201 (-4.3A)
FAD  B5201 (-4.6A)
FAD  B5201 (-3.0A)
FAD  B5201 (-3.7A)
FAD  B5201 (-3.8A)
FAD  B5201 (-3.8A)
FAD  B5201 (-4.1A)
 0.60A 4r3aB-3rh8B:
12.5		 4r3aB-3rh8B:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		7 / 12 ALA A 200
ILE A 161
ILE A 171
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-2.8A)
FMN  A5201 (-3.8A)
FMN  A5201 ( 4.4A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 1.42A 4r3aB-4wujA:
12.2		 4r3aB-4wujA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		8 / 12 CYH A 135
ARG A 136
ILE A 161
ILE A 171
ASN A 173
ASN A 183
GLY A 202
GLN A 204
 FMN  A5201 (-3.5A)
FMN  A5201 (-3.7A)
FMN  A5201 (-3.8A)
FMN  A5201 ( 4.4A)
FMN  A5201 (-2.4A)
FMN  A5201 (-4.1A)
FMN  A5201 (-3.0A)
FMN  A5201 (-3.7A)
 0.70A 4r3aB-4wujA:
12.2		 4r3aB-4wujA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		7 / 12 CYH B  54
ARG B  55
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLN B 126
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.8A)
 0.95A 4r3aB-5svwB:
13.9		 4r3aB-5svwB:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 5svw ADAGIO PROTEIN 1
(Arabidopsis
thaliana) 		7 / 12 CYH B  54
ARG B  55
ILE B  83
ASN B  95
ASN B 105
LEU B 107
GLY B 124
 FMN  B5201 (-3.3A)
FMN  B5201 (-3.8A)
FMN  B5201 (-4.2A)
FMN  B5201 (-2.4A)
FMN  B5201 (-3.8A)
FMN  B5201 ( 4.5A)
FMN  B5201 (-3.0A)
 0.63A 4r3aB-5svwB:
13.9		 4r3aB-5svwB:
19.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
None
 0.35A 4twlA-5cjfA:
27.8		 4twlA-5cjfA:
30.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 121
VAL A 143
THR A 199
TRP A 209
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
None
 0.33A 4twlB-5cjfA:
27.9		 4twlB-5cjfA:
30.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 2guu ODCASE
(Plasmodium
vivax) 		4 / 4 ALA A 299
VAL A 297
GLY A 273
THR A 226
 UP6  A5203 ( 3.9A)
None
UP6  A5203 ( 4.9A)
UP6  A5203 (-3.0A)
 1.08A 4ubeA-2guuA:
2.6		 4ubeA-2guuA:
20.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.86A 4uovA-5cjfA:
29.9		 4uovA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.32A 4uovA-5cjfA:
29.9		 4uovA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 4uovA-5cjfA:
29.9		 4uovA-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 4uovB-5cjfA:
29.9		 4uovB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.18A 4uovB-5cjfA:
29.9		 4uovB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.50A 4uovB-5cjfA:
29.9		 4uovB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.26A 4uovB-5cjfA:
29.9		 4uovB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.03A 4uovB-5cjfA:
29.9		 4uovB-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 4uovC-5cjfA:
29.9		 4uovC-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.22A 4uovC-5cjfA:
29.9		 4uovC-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.31A 4uovC-5cjfA:
29.9		 4uovC-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.06A 4uovC-5cjfA:
29.9		 4uovC-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 4uovD-5cjfA:
30.0		 4uovD-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.21A 4uovD-5cjfA:
30.0		 4uovD-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
THR A 199
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
 1.19A 4uovD-5cjfA:
30.0		 4uovD-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.29A 4uovD-5cjfA:
30.0		 4uovD-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 4uovD-5cjfA:
30.0		 4uovD-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.87A 4uovE-5cjfA:
30.0		 4uovE-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.30A 4uovE-5cjfA:
30.0		 4uovE-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 4uovE-5cjfA:
30.0		 4uovE-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 4uovF-5cjfA:
30.0		 4uovF-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.18A 4uovF-5cjfA:
30.0		 4uovF-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.29A 4uovF-5cjfA:
30.0		 4uovF-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.24A 4uovF-5cjfA:
30.0		 4uovF-5cjfA:
30.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 4uovF-5cjfA:
30.0		 4uovF-5cjfA:
30.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4URO_A_NOVA2000_1
(DNA GYRASE SUBUNIT B)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 ASP A 109
ARG A 158
ILE A 161
ILE A 187
ARG A 162
 None
FMN  A5201 (-3.7A)
FMN  A5201 (-3.8A)
FMN  A5201 (-4.0A)
SO4  A5202 ( 2.4A)
 1.35A 4uroA-4wujA:
undetectable		 4uroA-4wujA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.43A 4w5oA-1oahA:
0.0		 4w5oA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.44A 4w5rA-1oahA:
0.0		 4w5rA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.40A 4w5tA-1oahA:
0.0		 4w5tA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 5fca ACID
SPHINGOMYELINASE-LIK
E PHOSPHODIESTERASE
3A
(Mus
musculus) 		3 / 3 LYS A 402
ARG A 333
VAL A 348
 None
None
GOL  A 520 ( 4.5A)
 0.89A 4x3uA-5fcaA:
undetectable
4x3uB-5fcaA:
undetectable		 4x3uA-5fcaA:
10.73
4x3uB-5fcaA:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 4x5sA-5cjfA:
29.9		 4x5sA-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.25A 4x5sA-5cjfA:
29.9		 4x5sA-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.99A 4x5sA-5cjfA:
29.9		 4x5sA-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 4x5sB-5cjfA:
29.9		 4x5sB-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.17A 4x5sB-5cjfA:
29.9		 4x5sB-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.25A 4x5sB-5cjfA:
29.9		 4x5sB-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.00A 4x5sB-5cjfA:
29.9		 4x5sB-5cjfA:
28.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL
(Rattus
norvegicus) 		4 / 5 ALA A 326
THR A 330
VAL A 391
ILE A 500
 HEM  A 520 ( 3.3A)
HEM  A 520 ( 3.8A)
HEM  A 520 ( 4.8A)
None
 0.82A 4xe3A-3k9yA:
26.6		 4xe3A-3k9yA:
24.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
 0.90A 4xiwA-5cjfA:
26.2
4xiwH-5cjfA:
26.1		 4xiwA-5cjfA:
30.34
4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.43A 4xiwA-5cjfA:
26.2
4xiwH-5cjfA:
26.1		 4xiwA-5cjfA:
30.34
4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.23A 4xiwA-5cjfA:
26.2
4xiwH-5cjfA:
26.1		 4xiwA-5cjfA:
30.34
4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.90A 4xiwA-5cjfA:
26.2
4xiwH-5cjfA:
26.1		 4xiwA-5cjfA:
30.34
4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 4xiwB-5cjfA:
26.1
4xiwE-5cjfA:
26.3		 4xiwB-5cjfA:
30.34
4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.24A 4xiwB-5cjfA:
26.1
4xiwE-5cjfA:
26.3		 4xiwB-5cjfA:
30.34
4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.45A 4xiwB-5cjfA:
26.1
4xiwE-5cjfA:
26.3		 4xiwB-5cjfA:
30.34
4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 4xiwC-5cjfA:
26.1		 4xiwC-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.18A 4xiwC-5cjfA:
26.1		 4xiwC-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.36A 4xiwC-5cjfA:
26.1		 4xiwC-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.24A 4xiwC-5cjfA:
26.1		 4xiwC-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.87A 4xiwC-5cjfA:
26.1		 4xiwC-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 4xiwD-5cjfA:
26.4		 4xiwD-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.15A 4xiwD-5cjfA:
26.4		 4xiwD-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.42A 4xiwD-5cjfA:
26.4		 4xiwD-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.21A 4xiwD-5cjfA:
26.4		 4xiwD-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.91A 4xiwD-5cjfA:
26.4		 4xiwD-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
 1.00A 4xiwE-5cjfA:
26.3		 4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.44A 4xiwE-5cjfA:
26.3		 4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.25A 4xiwE-5cjfA:
26.3		 4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.98A 4xiwE-5cjfA:
26.3		 4xiwE-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 4xiwF-5cjfA:
26.1		 4xiwF-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.47A 4xiwF-5cjfA:
26.1		 4xiwF-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.23A 4xiwF-5cjfA:
26.1		 4xiwF-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.97A 4xiwF-5cjfA:
26.1		 4xiwF-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
GLU A 117
VAL A 121
LEU A 141
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
520  A 302 ( 4.9A)
None
520  A 302 ( 4.9A)
None
 1.40A 4xiwG-5cjfA:
26.2		 4xiwG-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		12 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 141
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.39A 4xiwG-5cjfA:
26.2		 4xiwG-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 141
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
None
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.20A 4xiwG-5cjfA:
26.2		 4xiwG-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  67
HIS A  96
GLU A 106
VAL A 121
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
GOL  A 303 ( 3.5A)
 1.01A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 11 GLN A  92
HIS A  94
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.43A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.27A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 0.96A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.93A 4xiwH-5cjfA:
26.1		 4xiwH-5cjfA:
30.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.39A 4ygfA-5cjfA:
25.9		 4ygfA-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.40A 4ygfB-5cjfA:
25.5		 4ygfB-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A 119
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 1.47A 4ygfB-5cjfA:
25.5		 4ygfB-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.40A 4ygfB-5cjfA:
25.5		 4ygfB-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.31A 4ygfC-5cjfA:
19.1		 4ygfC-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.27A 4ygfD-5cjfA:
4.1		 4ygfD-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.99A 4ygfD-5cjfA:
4.1		 4ygfD-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.36A 4ygfE-5cjfA:
26.0		 4ygfE-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.73A 4ygfE-5cjfA:
26.0		 4ygfE-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.42A 4ygfE-5cjfA:
26.0		 4ygfE-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.30A 4ygfF-5cjfA:
25.5		 4ygfF-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.23A 4ygfG-5cjfA:
6.3		 4ygfG-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.39A 4ygfG-5cjfA:
6.3		 4ygfG-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.04A 4ygfG-5cjfA:
6.3		 4ygfG-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.36A 4ygfH-5cjfA:
25.8		 4ygfH-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.51A 4yhaA-5cjfA:
25.6		 4yhaA-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.47A 4yhaB-5cjfA:
24.9		 4yhaB-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.42A 4yhaC-5cjfA:
25.8		 4yhaC-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.49A 4yhaC-5cjfA:
25.8		 4yhaC-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 11 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.47A 4yhaD-5cjfA:
24.8		 4yhaD-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.10A 4yhaD-5cjfA:
24.8		 4yhaD-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 0.55A 4yhaE-5cjfA:
25.9		 4yhaE-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  94
HIS A 119
LEU A 198
THR A 199
PRO A 201
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 1.46A 4yhaE-5cjfA:
25.9		 4yhaE-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.70A 4yhaF-5cjfA:
23.2		 4yhaF-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 12 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.42A 4yhaG-5cjfA:
25.5		 4yhaG-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 10 HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.47A 4yhaH-5cjfA:
25.5		 4yhaH-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 6 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.39A 4z4cA-1oahA:
undetectable		 4z4cA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.41A 4z4dA-1oahA:
undetectable		 4z4dA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.40A 4z4eA-1oahA:
0.0		 4z4eA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.36A 4z4hA-1oahA:
undetectable		 4z4hA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 4 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.34A 4z4iA-1oahA:
0.0		 4z4iA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 3rrk V-TYPE ATPASE 116
KDA SUBUNIT
(Meiothermus
ruber) 		4 / 7 GLU A 184
SER A 183
VAL A 180
ARG A 189
 None
None
NHE  A 520 ( 4.9A)
None
 1.36A 5adlA-3rrkA:
undetectable
5adlB-3rrkA:
undetectable		 5adlA-3rrkA:
23.40
5adlB-3rrkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		4 / 7 ILE A  81
LEU A  78
THR A 101
LEU A 100
 None
None
FMN  A5201 (-3.4A)
None
 0.91A 5b1bA-4wujA:
undetectable
5b1bJ-4wujA:
undetectable		 5b1bA-4wujA:
16.16
5b1bJ-4wujA:
14.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.99A 5c8iA-5cjfA:
36.9		 5c8iA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.16A 5c8iA-5cjfA:
36.9		 5c8iA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 GLN A  92
HIS A  94
HIS A  96
GLU A 106
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.40A 5c8iA-5cjfA:
36.9		 5c8iA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 HIS A  94
HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 5c8iA-5cjfA:
36.9		 5c8iA-5cjfA:
36.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.89A 5c8iA-5cjfA:
36.9		 5c8iA-5cjfA:
36.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3rrk V-TYPE ATPASE 116
KDA SUBUNIT
(Meiothermus
ruber) 		4 / 7 GLU A 184
SER A 183
VAL A 180
ARG A 189
 None
None
NHE  A 520 ( 4.9A)
None
 1.37A 5fj3A-3rrkA:
undetectable
5fj3B-3rrkA:
3.6		 5fj3A-3rrkA:
23.40
5fj3B-3rrkA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.94A 5ikrB-4wujA:
undetectable		 5ikrB-4wujA:
13.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.40A 5jn8A-5cjfA:
33.7		 5jn8A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 5jn8A-5cjfA:
33.7		 5jn8A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
GLU A 106
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.01A 5jn8B-5cjfA:
34.0		 5jn8B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
GLU A 117
HIS A 119
VAL A 121
VAL A 143
TRP A 209
 GOL  A 303 (-3.2A)
None
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
None
 1.48A 5jn8B-5cjfA:
34.0		 5jn8B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.39A 5jn8B-5cjfA:
34.0		 5jn8B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 5jn8B-5cjfA:
34.0		 5jn8B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.42A 5jn8C-5cjfA:
33.6		 5jn8C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.11A 5jn8C-5cjfA:
33.6		 5jn8C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  96
GLU A 106
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.89A 5jn8D-5cjfA:
33.4		 5jn8D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.34A 5jn8D-5cjfA:
33.4		 5jn8D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 5jn8D-5cjfA:
33.4		 5jn8D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.37A 5jn9A-5cjfA:
33.7		 5jn9A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.33A 5jn9A-5cjfA:
33.7		 5jn9A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 5jn9A-5cjfA:
33.7		 5jn9A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.03A 5jn9B-5cjfA:
34.1		 5jn9B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.36A 5jn9B-5cjfA:
34.1		 5jn9B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.36A 5jn9B-5cjfA:
34.1		 5jn9B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.98A 5jn9B-5cjfA:
34.1		 5jn9B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.33A 5jn9C-5cjfA:
33.7		 5jn9C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 9 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.37A 5jn9C-5cjfA:
33.7		 5jn9C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.02A 5jn9C-5cjfA:
33.7		 5jn9C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A 119
HIS A  96
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.47A 5jn9C-5cjfA:
33.7		 5jn9C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.34A 5jn9D-5cjfA:
33.3		 5jn9D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.32A 5jn9D-5cjfA:
33.3		 5jn9D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 5jn9D-5cjfA:
33.3		 5jn9D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.47A 5jnaA-5cjfA:
33.6		 5jnaA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
GLU A 106
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 5jnaA-5cjfA:
33.6		 5jnaA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.41A 5jnaA-5cjfA:
33.6		 5jnaA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 5jnaA-5cjfA:
33.6		 5jnaA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.47A 5jnaB-5cjfA:
34.0		 5jnaB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.00A 5jnaB-5cjfA:
34.0		 5jnaB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.37A 5jnaB-5cjfA:
34.0		 5jnaB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 5jnaB-5cjfA:
34.0		 5jnaB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 11 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.50A 5jnaC-5cjfA:
33.5		 5jnaC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.01A 5jnaC-5cjfA:
33.5		 5jnaC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.39A 5jnaC-5cjfA:
33.5		 5jnaC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.10A 5jnaC-5cjfA:
33.5		 5jnaC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 ASN A  62
GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.43A 5jnaD-5cjfA:
33.3		 5jnaD-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 GLN A  67
HIS A  94
HIS A  96
HIS A 119
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.01A 5jnaD-5cjfA:
33.3		 5jnaD-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 5jnaD-5cjfA:
33.3		 5jnaD-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 11 GLN A  92
HIS A  94
GLU A 117
VAL A 121
THR A 199
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
None
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
 1.25A 5jncA-5cjfA:
33.6		 5jncA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 11 GLN A  92
HIS A  94
HIS A  96
GLU A 106
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.39A 5jncA-5cjfA:
33.6		 5jncA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 11 HIS A  96
GLU A 106
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 4.6A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 5jncA-5cjfA:
33.6		 5jncA-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.32A 5jncB-5cjfA:
34.1		 5jncB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.36A 5jncB-5cjfA:
34.1		 5jncB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.99A 5jncB-5cjfA:
34.1		 5jncB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
THR A 199
THR A 200
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.44A 5jncB-5cjfA:
34.1		 5jncB-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.36A 5jncC-5cjfA:
33.6		 5jncC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.05A 5jncC-5cjfA:
33.6		 5jncC-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.34A 5jncD-5cjfA:
33.3		 5jncD-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.06A 5jncD-5cjfA:
33.3		 5jncD-5cjfA:
35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.45A 5js1A-1oahA:
undetectable		 5js1A-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 12 VAL A 201
LEU A 102
LEU A 203
VAL A  74
GLY A  76
 FMN  A5201 (-4.2A)
None
None
None
None
 0.91A 5jvzA-4wujA:
undetectable		 5jvzA-4wujA:
13.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.41A 5ku6A-5cjfA:
33.6		 5ku6A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 5ku6A-5cjfA:
33.6		 5ku6A-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.09A 5ku6B-5cjfA:
34.0		 5ku6B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 10 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.37A 5ku6B-5cjfA:
34.0		 5ku6B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
VAL A 207
THR A 199
THR A 200
TRP A 209
 ZN  A 301 (-3.2A)
None
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.33A 5ku6B-5cjfA:
34.0		 5ku6B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.03A 5ku6B-5cjfA:
34.0		 5ku6B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A 119
HIS A  96
VAL A 143
THR A 199
THR A 200
 ZN  A 301 ( 3.1A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.46A 5ku6B-5cjfA:
34.0		 5ku6B-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.41A 5ku6C-5cjfA:
33.7		 5ku6C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.11A 5ku6C-5cjfA:
33.7		 5ku6C-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 GLN A  67
HIS A  94
HIS A  96
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.10A 5ku6D-5cjfA:
33.3		 5ku6D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 9 GLN A  92
HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.38A 5ku6D-5cjfA:
33.3		 5ku6D-5cjfA:
35.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.07A 5ku6D-5cjfA:
33.3		 5ku6D-5cjfA:
35.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L0Z_B_SAMB304_0
(PROBABLE RNA
METHYLTRANSFERASE,
TRMH FAMILY)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		5 / 10 LEU A 138
GLY A 202
ILE A 130
LEU A 100
ALA A 115
 FMN  A5201 (-3.7A)
FMN  A5201 (-3.0A)
None
None
None
 0.82A 5l0zB-4wujA:
undetectable		 5l0zB-4wujA:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5L8D_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		8 / 8 TYR A  22
MET A  27
ARG A  97
TRP A 100
ARG A 137
TRP A 398
TYR A 402
THR A 490
 BHR  A 520 (-4.2A)
BHR  A 520 (-3.7A)
BHR  A 520 ( 2.9A)
BHR  A 520 (-3.5A)
BHR  A 520 (-3.8A)
BHR  A 520 (-3.8A)
BHR  A 520 ( 4.6A)
BHR  A 520 (-4.4A)
 0.19A 5l8dA-3mzbA:
61.1		 5l8dA-3mzbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3k9y 1,25-DIHYDROXYVITAMI
N D(3)
24-HYDROXYLASE,
MITOCHONDRIAL
(Rattus
norvegicus) 		5 / 11 CYH A 462
ALA A 327
ALA A 468
THR A 331
LEU A 371
 HEM  A 520 ( 2.2A)
HEM  A 520 ( 3.4A)
HEM  A 520 ( 4.0A)
HEM  A 520 ( 4.7A)
None
 1.13A 5lf7V-3k9yA:
undetectable
5lf7W-3k9yA:
undetectable		 5lf7V-3k9yA:
17.93
5lf7W-3k9yA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5kc9 GLUTAMATE RECEPTOR
IONOTROPIC, DELTA-1
(Mus
musculus) 		4 / 8 LEU A 270
LEU A 231
ILE A 318
GLN A 283
 BU1  A 520 (-4.1A)
None
None
None
 1.04A 5ljbA-5kc9A:
undetectable		 5ljbA-5kc9A:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 7 GLN A  92
HIS A  94
VAL A 121
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.37A 5m78A-5cjfA:
36.6		 5m78A-5cjfA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 7 GLN A  92
HIS A  94
VAL A 121
LEU A 198
THR A 200
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.34A 5m78A-5cjfA:
36.6		 5m78A-5cjfA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 7 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
None
520  A 302 ( 4.9A)
 1.06A 5m8rA-5cjfA:
undetectable		 5m8rA-5cjfA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 8 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
None
520  A 302 ( 4.9A)
 1.03A 5m8rC-5cjfA:
undetectable		 5m8rC-5cjfA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 8 HIS A  96
HIS A 119
LEU A 118
VAL A 121
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
None
520  A 302 ( 4.9A)
 1.01A 5m8rD-5cjfA:
undetectable		 5m8rD-5cjfA:
20.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MWU_A_EDTA609_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 3mzb NICKEL-BINDING
PERIPLASMIC PROTEIN
(Escherichia
coli) 		8 / 8 TYR A  22
MET A  27
ARG A  97
TRP A 100
ARG A 137
TRP A 398
TYR A 402
THR A 490
 BHR  A 520 (-4.2A)
BHR  A 520 (-3.7A)
BHR  A 520 ( 2.9A)
BHR  A 520 (-3.5A)
BHR  A 520 (-3.8A)
BHR  A 520 (-3.8A)
BHR  A 520 ( 4.6A)
BHR  A 520 (-4.4A)
 0.19A 5mwuA-3mzbA:
61.1		 5mwuA-3mzbA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 4qhx UNCHARACTERIZED
PROTEIN
(Bacteroides
caccae) 		4 / 6 ARG A 157
GLY A 155
THR A 362
SER A 160
 PEG  A 520 ( 4.4A)
None
PEG  A 519 (-4.2A)
SO4  A 508 (-3.8A)
 1.06A 5ny7A-4qhxA:
undetectable		 5ny7A-4qhxA:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.24A 5ogjA-5cjfA:
36.5		 5ogjA-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.24A 5ogjA-5cjfA:
36.5		 5ogjA-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.23A 5ogjB-5cjfA:
36.1		 5ogjB-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.24A 5ogjB-5cjfA:
36.1		 5ogjB-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 5 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.24A 5ohhA-5cjfA:
36.2		 5ohhA-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 5 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 0.24A 5ohhA-5cjfA:
36.2		 5ohhA-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		4 / 6 HIS A  94
HIS A  96
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.23A 5ohhB-5cjfA:
36.5		 5ohhB-5cjfA:
37.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 6 HIS A  94
HIS A 119
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.21A 5ohhB-5cjfA:
36.5		 5ohhB-5cjfA:
37.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 0.52A 5tt3A-5cjfA:
25.7		 5tt3A-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 10 HIS A  94
HIS A  96
VAL A 121
LEU A 198
PRO A 202
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
None
 1.10A 5tt3A-5cjfA:
25.7		 5tt3A-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.37A 5tt3B-5cjfA:
24.0		 5tt3B-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 10 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
PRO A 202
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
None
 0.47A 5tt3C-5cjfA:
25.8		 5tt3C-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 10 HIS A  96
HIS A  94
VAL A 121
LEU A 198
THR A 199
PRO A 202
 ZN  A 301 ( 3.2A)
ZN  A 301 (-3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 1.45A 5tt3C-5cjfA:
25.8		 5tt3C-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.36A 5tt3E-5cjfA:
25.9		 5tt3E-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.03A 5tt3E-5cjfA:
25.9		 5tt3E-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.50A 5tt3F-5cjfA:
24.9		 5tt3F-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 8 HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 200
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
 1.48A 5tt3F-5cjfA:
24.9		 5tt3F-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		8 / 9 HIS A  94
HIS A  96
HIS A 119
VAL A 121
VAL A 143
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.35A 5tt3G-5cjfA:
24.9		 5tt3G-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 9 HIS A  96
HIS A 119
VAL A 143
LEU A 198
THR A 199
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
 1.04A 5tt3G-5cjfA:
24.9		 5tt3G-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 8 HIS A  94
HIS A  96
HIS A 119
VAL A 121
LEU A 198
THR A 199
TRP A 209
 ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.1A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
None
 0.44A 5tt3H-5cjfA:
25.3		 5tt3H-5cjfA:
28.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		4 / 7 ILE A  81
LEU A  78
THR A 101
LEU A 100
 None
None
FMN  A5201 (-3.4A)
None
 0.89A 5xdqA-4wujA:
undetectable
5xdqJ-4wujA:
undetectable		 5xdqA-4wujA:
16.16
5xdqJ-4wujA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4wuj GLYCOSIDE HYDROLASE
FAMILY 15, CELLULOSE
SIGNALING ASSOCIATED
PROTEIN ENVOY
(Trichoderma
reesei) 		4 / 8 ILE A  81
LEU A  78
THR A 101
LEU A 100
 None
None
FMN  A5201 (-3.4A)
None
 0.92A 5zcoA-4wujA:
undetectable
5zcoJ-4wujA:
undetectable		 5zcoA-4wujA:
16.16
5zcoJ-4wujA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4mzy NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE
(Enterococcus
faecalis) 		4 / 4 ARG A 164
SER A 292
ASP A 264
HIS A 205
 CL  A 518 (-3.9A)
None
FMT  A 520 ( 4.5A)
MLA  A 515 (-3.9A)
 1.27A 5zhmA-4mzyA:
0.3		 5zhmA-4mzyA:
18.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6AN0_A_HISA520_0
(HISTIDINOL
DEHYDROGENASE)		 6an0 HISTIDINOL
DEHYDROGENASE
(Elizabethkingia
anophelis) 		6 / 6 GLU A  98
LYS A 100
ARG A 113
GLU A 114
ALA A 115
LYS A 385
 HIS  A 520 (-3.5A)
None
HIS  A 520 (-4.9A)
HIS  A 520 (-4.4A)
HIS  A 520 (-3.5A)
HIS  A 520 (-3.7A)
 0.00A 6an0A-6an0A:
60.4		 6an0A-6an0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
TRP A 209
 GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.13A 6bbsA-5cjfA:
29.6		 6bbsA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 TRP A   5
ASN A  62
HIS A  64
GLN A  92
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
GOL  A 303 (-3.9A)
None
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 0.52A 6bbsA-5cjfA:
29.6		 6bbsA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 TRP A   5
HIS A  64
HIS A  94
LEU A 198
THR A 199
THR A 200
TRP A 209
 None
None
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
 1.48A 6bbsA-5cjfA:
29.6		 6bbsA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		11 / 12 TRP A   5
ASN A  62
GLN A  92
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
GOL  A 303 (-3.9A)
GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.46A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		7 / 12 TRP A   5
GLN A  67
HIS A  94
HIS A  96
LEU A 198
THR A 199
THR A 200
 None
GOL  A 303 (-3.4A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.15A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  94
LEU A 198
THR A 200
PRO A 202
TRP A 209
 None
ZN  A 301 (-3.2A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
None
 1.30A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		6 / 12 TRP A   5
HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 None
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.08A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		9 / 12 TRP A  16
HIS A  94
HIS A  96
VAL A 121
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 None
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 1.44A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 5 HIS A  64
GLU A 106
HIS A 119
LEU A 141
VAL A 143
 None
ZN  A 301 ( 4.6A)
ZN  A 301 ( 3.1A)
None
520  A 302 ( 4.9A)
 0.18A 6bc9A-5cjfA:
36.8		 6bc9A-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 GLN A  67
HIS A  96
LEU A 198
THR A 199
THR A 200
 GOL  A 303 (-3.4A)
ZN  A 301 ( 3.2A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 1.04A 6bccA-5cjfA:
36.9		 6bccA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		10 / 12 GLN A  92
HIS A  94
HIS A  96
VAL A 121
VAL A 143
LEU A 198
THR A 199
THR A 200
PRO A 202
TRP A 209
 GOL  A 303 (-3.2A)
ZN  A 301 (-3.2A)
ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
None
None
 0.38A 6bccA-5cjfA:
36.9		 6bccA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 121
LEU A 198
THR A 200
PRO A 202
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
GOL  A 303 ( 3.5A)
None
 0.83A 6bccA-5cjfA:
36.9		 6bccA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 5cjf CARBONIC ANHYDRASE
14
(Homo
sapiens) 		5 / 12 HIS A  96
VAL A 143
LEU A 198
THR A 199
THR A 200
 ZN  A 301 ( 3.2A)
520  A 302 ( 4.9A)
520  A 302 (-3.6A)
520  A 302 (-3.4A)
GOL  A 303 ( 3.5A)
 0.95A 6bccA-5cjfA:
36.9		 6bccA-5cjfA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4mzy NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE
(Enterococcus
faecalis) 		5 / 12 LEU A 158
GLY A 314
VAL A 275
ILE A 263
ASP A 264
 None
None
None
None
FMT  A 520 ( 4.5A)
 1.11A 6bxmA-4mzyA:
undetectable		 6bxmA-4mzyA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA901_0
(PROTEIN ARGONAUTE-2)		 1oah CYTOCHROME C NITRITE
REDUCTASE
(Desulfovibrio
desulfuricans) 		4 / 5 TYR A 112
LYS A  81
GLU A 114
TYR A  79
 HEM  A1520 (-4.9A)
None
CA  A1526 ( 3.4A)
None
 1.46A 6cbdA-1oahA:
undetectable		 6cbdA-1oahA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 2zl5 58 KD CAPSID PROTEIN
(Norwalk
virus) 		5 / 10 LEU A 304
ASP A 305
ILE A 359
PRO A 354
GLY A 357
 ACT  A 520 ( 4.0A)
None
None
None
None
 1.31A 6dm0B-2zl5A:
undetectable
6dm0C-2zl5A:
undetectable		 6dm0B-2zl5A:
15.16
6dm0C-2zl5A:
15.16