SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ZN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_B_RABB602_1
(ADENOSYLHOMOCYSTEINA
SE)		 5cbm M17 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		5 / 12 THR A 465
ASP A 399
LYS A 386
ASP A 459
LEU A 487
 None
ZN  A 702 ( 2.3A)
4ZN  A 704 ( 2.5A)
ZN  A 703 ( 2.9A)
CO3  A 701 ( 4.5A)
 1.33A 3glqB-5cbmA:
undetectable		 3glqB-5cbmA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5cbm M17 FAMILY
AMINOPEPTIDASE
(Plasmodium
falciparum) 		3 / 3 ASP A 379
PHE A 398
SER A 391
 ZN  A 703 (-2.3A)
4ZN  A 704 (-4.9A)
SO4  A 709 (-3.9A)
 0.97A 3i5uB-5cbmA:
undetectable		 3i5uB-5cbmA:
19.96