SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4UD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 5bpk GAMMA-GLUTAMYLTRANSP
EPTIDASE (GGT)
(Helicobacter
pylori) 		5 / 12 ILE C 476
GLY C 473
GLY C 472
THR C 396
ASN C 400
 None
4UD  C 701 (-3.5A)
4UD  C 701 (-4.4A)
None
4UD  C 701 (-3.4A)
 1.01A 1likA-5bpkC:
undetectable		 1likA-5bpkC:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5bpk GAMMA-GLUTAMYLTRANSP
EPTIDASE (GGT)
(Helicobacter
pylori) 		3 / 3 ASN C 418
ASP C 422
ARG C 513
 None
4UD  C 701 ( 3.0A)
None
 0.85A 3k13A-5bpkC:
undetectable		 3k13A-5bpkC:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FO4_A_MOAA502_1
(INOSINE
5'-MONOPHOSPHATE
DEHYDROGENASE)		 5bpk GAMMA-GLUTAMYLTRANSP
EPTIDASE (GGT)
(Helicobacter
pylori) 		4 / 8 ASP C 562
ASN C 544
THR C 396
GLY C 472
 None
None
None
4UD  C 701 (-4.4A)
 0.93A 4fo4A-5bpkC:
undetectable		 4fo4A-5bpkC:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)		 5bpk GAMMA-GLUTAMYLTRANSP
EPTIDASE (GGT)
(Helicobacter
pylori) 		3 / 3 MET C 540
HIS C 504
GLY C 473
 None
None
4UD  C 701 (-3.5A)
 0.83A 5gwzB-5bpkC:
undetectable		 5gwzB-5bpkC:
23.08