SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4RA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_A_SAMA293_0 (GLYCINE N-METHYLTRANSFERASE)	4ztc	AMINOTRANSFERASE HOMOLOG (Campylobacter jejuni)	5 / 12	ILE A 237 GLY A 182 SER A 6 GLY A 191 SER A 179	None 4RA A 401 (-3.1A) None None 4RA A 401 (-2.6A)	1.16A	1nbiA-4ztcA: undetectable	1nbiA-4ztcA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBI_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	4ztc	AMINOTRANSFERASE HOMOLOG (Campylobacter jejuni)	5 / 12	ILE A 237 GLY A 182 SER A 6 GLY A 191 SER A 179	None 4RA A 401 (-3.1A) None None 4RA A 401 (-2.6A)	1.16A	1nbiB-4ztcA: undetectable	1nbiB-4ztcA: 21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X2N_B_X2NB1479_1 (LANOSTEROL 14-ALPHA-DEMETHYLASE)	4ztc	AMINOTRANSFERASE HOMOLOG (Campylobacter jejuni)	5 / 12	TYR A 180 PRO A 29 ALA A 28 ALA A 56 ALA A 59	None None None 4RA A 401 (-3.4A) None	1.30A	2x2nB-4ztcA: undetectable	2x2nB-4ztcA: 21.69