SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4MD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 7 HIS A  95
HIS A  97
HIS A 120
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.40A 1am6A-3da2A:
42.0		 1am6A-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 HIS A  95
HIS A  97
HIS A 120
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 1azmA-3da2A:
42.0		 1azmA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 PHE A 132
HIS A  95
HIS A  97
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-4.6A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.00A 1azmA-3da2A:
42.0		 1azmA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 HIS A  95
HIS A  97
HIS A 120
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.50A 1bzmA-3da2A:
42.1		 1bzmA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 PHE A 132
HIS A  95
HIS A  97
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-4.6A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.00A 1bzmA-3da2A:
42.1		 1bzmA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 HIS A  65
GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 1cilA-3da2A:
42.1		 1cilA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 HIS A  65
GLN A  93
HIS A  97
PHE A 132
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 1cilA-3da2A:
42.1		 1cilA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  65
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 1cilA-3da2A:
42.1		 1cilA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  65
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.29A 1cilA-3da2A:
42.1		 1cilA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 142
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
None
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.55A 1dmyA-3da2A:
37.4		 1dmyA-3da2A:
45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.85A 1dmyB-3da2A:
37.4		 1dmyB-3da2A:
45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 1dmyB-3da2A:
37.4		 1dmyB-3da2A:
45.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.64A 1jd0A-3da2A:
36.3		 1jd0A-3da2A:
36.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.63A 1jd0B-3da2A:
36.0		 1jd0B-3da2A:
36.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 1jd0B-3da2A:
36.0		 1jd0B-3da2A:
36.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
GLN A  93
HIS A  95
PHE A 132
LEU A 199
PRO A 203
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 0.93A 1oq5A-3da2A:
42.5		 1oq5A-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 ASN A  68
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.49A 1oq5A-3da2A:
42.5		 1oq5A-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.74A 1rj6A-3da2A:
36.7		 1rj6A-3da2A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.74A 1rj6B-3da2A:
36.4		 1rj6B-3da2A:
36.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
HIS A  95
VAL A 122
PHE A 132
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 1.00A 1ydaA-3da2A:
41.5		 1ydaA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 HIS A  95
HIS A 120
VAL A 122
PHE A 132
VAL A 144
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
None
 0.45A 1ydaA-3da2A:
41.5		 1ydaA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 0.95A 1ydbA-3da2A:
41.7		 1ydbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
None
 0.46A 1ydbA-3da2A:
41.7		 1ydbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  95
HIS A  97
VAL A 122
PHE A 132
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 1.48A 1ydbA-3da2A:
41.7		 1ydbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
VAL A 144
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
 0.89A 1yddA-3da2A:
42.1		 1yddA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
 0.48A 1yddA-3da2A:
42.1		 1yddA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.94A 1z9yA-3da2A:
42.1		 1z9yA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 GLN A  93
HIS A  97
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 1z9yA-3da2A:
42.1		 1z9yA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 1z9yA-3da2A:
42.1		 1z9yA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.40A 1z9yA-3da2A:
42.1		 1z9yA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 ASN A  68
GLN A  93
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 1zgfA-3da2A:
42.3		 1zgfA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 ASN A  68
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.55A 1zgfA-3da2A:
42.3		 1zgfA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 GLN A  93
HIS A  95
HIS A  97
GLU A 107
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.66A 1zsbA-3da2A:
42.5		 1zsbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.39A 1zsbA-3da2A:
42.5		 1zsbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 1zsbA-3da2A:
42.5		 1zsbA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 142
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
None
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 2aw1A-3da2A:
42.0		 2aw1A-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
VAL A 122
LEU A 142
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
None
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.40A 2aw1A-3da2A:
42.0		 2aw1A-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 6 TRP A   6
ASN A  68
GLN A  93
PRO A 203
 None
None
4MD  A 401 (-3.1A)
4MD  A 401 ( 4.9A)
 0.93A 2ez7A-3da2A:
41.6		 2ez7A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 8 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.41A 2gehA-3da2A:
42.0		 2gehA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 9 GLN A  93
HIS A  97
VAL A 122
PHE A 132
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
None
 0.67A 2h4nA-3da2A:
42.4		 2h4nA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 9 HIS A  97
HIS A 120
VAL A 122
PHE A 132
THR A 200
TRP A 210
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
None
 0.23A 2h4nA-3da2A:
42.4		 2h4nA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 HIS A  95
HIS A  97
HIS A 120
VAL A 144
LEU A 199
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.47A 2it4A-3da2A:
42.5		 2it4A-3da2A:
60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 8 HIS A  97
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.74A 2it4A-3da2A:
42.5		 2it4A-3da2A:
60.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 ASN A  68
GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.96A 2pouA-3da2A:
42.1		 2pouA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 ASN A  68
HIS A  95
HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.61A 2pouA-3da2A:
42.1		 2pouA-3da2A:
60.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 7 PHE A 132
VAL A 201
VAL A 144
VAL A 208
 4MD  A 401 (-4.6A)
4MD  A 401 ( 4.2A)
4MD  A 401 ( 4.4A)
None
 0.99A 2qbnA-3da2A:
undetectable		 2qbnA-3da2A:
19.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  97
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.03A 3bl1A-3da2A:
41.9		 3bl1A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.96A 3bl1A-3da2A:
41.9		 3bl1A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 3bl1A-3da2A:
41.9		 3bl1A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.48A 3cajA-3da2A:
42.0		 3cajA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  95
HIS A  97
VAL A 144
LEU A 199
PRO A 203
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.27A 3cajA-3da2A:
42.0		 3cajA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		11 / 12 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
VAL A 201
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.2A)
None
 0.60A 3czvA-3da2A:
45.6
3czvB-3da2A:
45.9		 3czvA-3da2A:
100.00
3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
VAL A 122
LEU A 199
THR A 200
VAL A 201
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.2A)
 0.91A 3czvA-3da2A:
45.6
3czvB-3da2A:
45.9		 3czvA-3da2A:
100.00
3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 10 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
VAL A 201
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.2A)
None
 0.65A 3czvB-3da2A:
45.9		 3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  95
HIS A  97
VAL A 144
LEU A 199
VAL A 201
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.2A)
 1.29A 3czvB-3da2A:
45.9		 3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
LEU A 199
THR A 200
VAL A 201
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.2A)
 0.94A 3czvB-3da2A:
45.9		 3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A 120
HIS A  97
VAL A 144
LEU A 199
VAL A 201
 ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.2A)
 1.40A 3czvB-3da2A:
45.9		 3czvB-3da2A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.85A 3dazA-3da2A:
42.5		 3dazA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 3dazA-3da2A:
42.5		 3dazA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 GLN A  93
HIS A  95
HIS A  97
GLU A 107
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.70A 3dc3A-3da2A:
42.4		 3dc3A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 3dc3A-3da2A:
42.4		 3dc3A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 3dc3A-3da2A:
42.4		 3dc3A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.69A 3dcsA-3da2A:
42.3		 3dcsA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.41A 3dcwA-3da2A:
42.5		 3dcwA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  95
HIS A  97
VAL A 144
LEU A 199
PRO A 203
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.30A 3dcwA-3da2A:
42.5		 3dcwA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.93A 3dcwA-3da2A:
42.5		 3dcwA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.44A 3dd0A-3da2A:
42.4		 3dd0A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  95
HIS A  97
VAL A 144
LEU A 199
PRO A 203
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.29A 3dd0A-3da2A:
42.4		 3dd0A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.93A 3dd0A-3da2A:
42.4		 3dd0A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
GLN A  93
HIS A  95
HIS A  97
LEU A 199
PRO A 203
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 0.93A 3f4xA-3da2A:
41.8		 3f4xA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 ASN A  68
HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.55A 3f4xA-3da2A:
41.8		 3f4xA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
HIS A  97
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 1.11A 3f4xA-3da2A:
41.8		 3f4xA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
HIS A  97
VAL A 144
LEU A 199
THR A 200
PRO A 203
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 1.03A 3f4xA-3da2A:
41.8		 3f4xA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 HIS A  95
HIS A  97
VAL A 144
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 1.24A 3f4xA-3da2A:
41.8		 3f4xA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  65
GLN A  93
HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.68A 3fw3A-3da2A:
32.1		 3fw3A-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 3fw3B-3da2A:
31.8		 3fw3B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 ASN A  68
GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
 0.95A 3hkuA-3da2A:
42.0		 3hkuA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 ASN A  68
HIS A  95
HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
None
 0.56A 3hkuA-3da2A:
42.0		 3hkuA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		3 / 3 GLU A 107
HIS A 120
THR A 200
 ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-3.2A)
 0.21A 3hkuA-3da2A:
42.0		 3hkuA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 11 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 3hs4A-3da2A:
42.5		 3hs4A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 3hs4A-3da2A:
42.5		 3hs4A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 3iaiA-3da2A:
34.0		 3iaiA-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 3iaiA-3da2A:
34.0		 3iaiA-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 3iaiB-3da2A:
33.8		 3iaiB-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 3iaiB-3da2A:
33.8		 3iaiB-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 3iaiC-3da2A:
33.8		 3iaiC-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 3iaiC-3da2A:
33.8		 3iaiC-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.88A 3iaiD-3da2A:
33.8		 3iaiD-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 3iaiD-3da2A:
33.8		 3iaiD-3da2A:
35.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
PHE A 132
LEU A 199
PRO A 203
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.03A 3kwaA-3da2A:
41.7		 3kwaA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.49A 3kwaA-3da2A:
41.7		 3kwaA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 11 HIS A  95
HIS A 120
VAL A 144
LEU A 199
THR A 200
PRO A 202
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
None
 1.49A 3kwaA-3da2A:
41.7		 3kwaA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  95
VAL A 144
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 1.31A 3kwaA-3da2A:
41.7		 3kwaA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 HIS A  97
HIS A 120
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 1.42A 3kwaA-3da2A:
41.7		 3kwaA-3da2A:
60.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LW5_B_PQNB5002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 ILE A  23
PHE A 132
ALA A 143
LEU A 142
ALA A 135
 None
4MD  A 401 (-4.6A)
None
None
None
 1.06A 3lw5B-3da2A:
undetectable		 3lw5B-3da2A:
16.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 PHE A 132
HIS A  97
VAL A 122
LEU A 199
THR A 200
 4MD  A 401 (-4.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.35A 3lxeA-3da2A:
42.6		 3lxeA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 SER A  66
GLN A  93
HIS A  95
HIS A  97
VAL A 144
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.79A 3lxeA-3da2A:
42.6		 3lxeA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 SER A  66
PHE A 132
HIS A  95
HIS A  97
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
4MD  A 401 (-4.6A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.04A 3lxeA-3da2A:
42.6		 3lxeA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  65
SER A  63
PHE A 132
VAL A 122
LEU A 199
 None
None
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
 1.18A 3lxeB-3da2A:
42.7		 3lxeB-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 PHE A 132
HIS A  97
VAL A 122
LEU A 199
THR A 200
 4MD  A 401 (-4.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.35A 3lxeB-3da2A:
42.7		 3lxeB-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 SER A  66
GLN A  93
HIS A  95
HIS A  97
VAL A 144
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.83A 3lxeB-3da2A:
42.7		 3lxeB-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 SER A  66
PHE A 132
HIS A  95
HIS A  97
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
4MD  A 401 (-4.6A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.06A 3lxeB-3da2A:
42.7		 3lxeB-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
ALA A 136
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-3.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.56A 3mdzA-3da2A:
41.4		 3mdzA-3da2A:
51.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 144
LEU A 199
PRO A 203
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.00A 3mdzA-3da2A:
41.4		 3mdzA-3da2A:
51.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
PHE A 132
LEU A 199
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
 1.00A 3ml5A-3da2A:
42.4		 3ml5A-3da2A:
53.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 3ml5A-3da2A:
42.4		 3ml5A-3da2A:
53.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 11 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.92A 3v2jA-3da2A:
42.5		 3v2jA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 3v2jA-3da2A:
42.5		 3v2jA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
HIS A  95
HIS A  97
PHE A 132
LEU A 199
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
 1.01A 3v2mA-3da2A:
42.4		 3v2mA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
PHE A 132
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 3v2mA-3da2A:
42.4		 3v2mA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 8 GLN A  93
HIS A  95
HIS A  97
LEU A 199
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
 0.82A 3w6hA-3da2A:
42.1		 3w6hA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 8 HIS A  95
HIS A  97
HIS A 120
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 3w6hA-3da2A:
42.1		 3w6hA-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
GLU A 107
HIS A 120
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.49A 3w6hB-3da2A:
42.1		 3w6hB-3da2A:
59.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 GLN A  93
HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.75A 3zncA-3da2A:
31.2		 3zncA-3da2A:
32.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 7 LEU A 199
GLU A 118
HIS A 120
HIS A  95
 4MD  A 401 (-4.2A)
None
ZN  A 301 ( 3.2A)
ZN  A 301 ( 3.6A)
 1.14A 4aq7A-3da2A:
undetectable		 4aq7A-3da2A:
14.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4coqA-3da2A:
31.4		 4coqA-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 4coqB-3da2A:
31.2		 4coqB-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
PHE A 132
LEU A 142
LEU A 199
VAL A 208
 4MD  A 401 (-3.1A)
4MD  A 401 (-4.6A)
None
4MD  A 401 (-4.2A)
None
 1.02A 4e3hA-3da2A:
42.2		 4e3hA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 VAL A 122
PHE A 132
LEU A 142
VAL A 144
LEU A 199
THR A 200
VAL A 208
TRP A 210
 4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
None
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
None
 0.35A 4e3hA-3da2A:
42.2		 4e3hA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 11 GLN A  93
HIS A  95
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 4g0cA-3da2A:
42.3		 4g0cA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
PHE A 132
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4g0cA-3da2A:
42.3		 4g0cA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 4g7aA-3da2A:
29.2		 4g7aA-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4g7aA-3da2A:
29.2		 4g7aA-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.84A 4g7aA-3da2A:
29.2		 4g7aA-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.88A 4g7aB-3da2A:
29.2		 4g7aB-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4g7aB-3da2A:
29.2		 4g7aB-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.85A 4g7aB-3da2A:
29.2		 4g7aB-3da2A:
31.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4k0sA-3da2A:
42.4		 4k0sA-3da2A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 199
PRO A 203
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 0.94A 4k0zA-3da2A:
42.3		 4k0zA-3da2A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.42A 4k0zA-3da2A:
42.3		 4k0zA-3da2A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.90A 4k0zA-3da2A:
42.3		 4k0zA-3da2A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 142
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
None
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4k13A-3da2A:
42.5		 4k13A-3da2A:
58.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.96A 4lu3A-3da2A:
36.1		 4lu3A-3da2A:
38.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 4lu3A-3da2A:
36.1		 4lu3A-3da2A:
38.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
HIS A  97
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 1.11A 4m2rA-3da2A:
42.5		 4m2rA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  97
VAL A 144
LEU A 199
PRO A 203
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 ( 4.9A)
 1.02A 4m2rA-3da2A:
42.5		 4m2rA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 GLN A  93
HIS A  95
HIS A  97
PHE A 132
LEU A 199
THR A 200
PRO A 203
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.90A 4m2rA-3da2A:
42.5		 4m2rA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.45A 4m2rA-3da2A:
42.5		 4m2rA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.97A 4m2rA-3da2A:
42.5		 4m2rA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A   6
HIS A  65
GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 None
None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.87A 4m2uA-3da2A:
42.4		 4m2uA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A   6
HIS A  65
GLN A  93
HIS A  97
PHE A 132
LEU A 199
THR A 200
 None
None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 4m2uA-3da2A:
42.4		 4m2uA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 TRP A   6
HIS A  65
HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4m2uA-3da2A:
42.4		 4m2uA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 TRP A   6
HIS A  65
HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.32A 4m2uA-3da2A:
42.4		 4m2uA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A  17
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.40A 4m2uA-3da2A:
42.4		 4m2uA-3da2A:
59.16
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.92A 4m2vA-3da2A:
42.3		 4m2vA-3da2A:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4m2vA-3da2A:
42.3		 4m2vA-3da2A:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 142
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
None
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4m2wA-3da2A:
42.4		 4m2wA-3da2A:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 142
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
None
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4m2wA-3da2A:
42.4		 4m2wA-3da2A:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 8 GLN A  93
HIS A  97
PHE A 132
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 0.89A 4n16A-3da2A:
42.6		 4n16A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 8 HIS A  95
HIS A  97
HIS A 120
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-3.2A)
 0.52A 4n16A-3da2A:
42.6		 4n16A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		4 / 8 HIS A  97
HIS A 120
PHE A 132
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 0.22A 4n16A-3da2A:
42.6		 4n16A-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 9 GLN A  93
HIS A  95
HIS A  97
PHE A 132
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 1.02A 4pxxA-3da2A:
42.4		 4pxxA-3da2A:
59.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 9 HIS A  95
HIS A  97
HIS A 120
PHE A 132
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.6A)
4MD  A 401 (-3.2A)
 0.59A 4pxxA-3da2A:
42.4		 4pxxA-3da2A:
59.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
VAL A 144
THR A 200
TRP A 210
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
None
 0.28A 4twlA-3da2A:
28.6		 4twlA-3da2A:
28.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
VAL A 144
THR A 200
TRP A 210
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-3.2A)
None
 0.25A 4twlB-3da2A:
28.6		 4twlB-3da2A:
28.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4uovA-3da2A:
31.0		 4uovA-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 4uovA-3da2A:
31.0		 4uovA-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.83A 4uovA-3da2A:
31.0		 4uovA-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4uovB-3da2A:
31.1		 4uovB-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4uovB-3da2A:
31.1		 4uovB-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.85A 4uovB-3da2A:
31.1		 4uovB-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4uovC-3da2A:
30.9		 4uovC-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 4uovC-3da2A:
30.9		 4uovC-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.82A 4uovC-3da2A:
30.9		 4uovC-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 4uovD-3da2A:
31.0		 4uovD-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4uovD-3da2A:
31.0		 4uovD-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.82A 4uovD-3da2A:
31.0		 4uovD-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4uovE-3da2A:
31.1		 4uovE-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4uovE-3da2A:
31.1		 4uovE-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.83A 4uovE-3da2A:
31.1		 4uovE-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4uovF-3da2A:
31.1		 4uovF-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 4uovF-3da2A:
31.1		 4uovF-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.82A 4uovF-3da2A:
31.1		 4uovF-3da2A:
33.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 4x5sA-3da2A:
29.5		 4x5sA-3da2A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 4x5sA-3da2A:
29.5		 4x5sA-3da2A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.87A 4x5sA-3da2A:
29.5		 4x5sA-3da2A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 4x5sB-3da2A:
29.6		 4x5sB-3da2A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4x5sB-3da2A:
29.6		 4x5sB-3da2A:
34.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 4xiwA-3da2A:
25.8
4xiwH-3da2A:
25.6		 4xiwA-3da2A:
30.74
4xiwH-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.84A 4xiwA-3da2A:
25.8
4xiwH-3da2A:
25.6		 4xiwA-3da2A:
30.74
4xiwH-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.92A 4xiwB-3da2A:
25.7
4xiwE-3da2A:
25.7		 4xiwB-3da2A:
30.74
4xiwE-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 4xiwB-3da2A:
25.7
4xiwE-3da2A:
25.7		 4xiwB-3da2A:
30.74
4xiwE-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 4xiwC-3da2A:
25.6		 4xiwC-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.93A 4xiwD-3da2A:
25.7		 4xiwD-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4xiwD-3da2A:
25.7		 4xiwD-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.89A 4xiwD-3da2A:
25.7		 4xiwD-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 4xiwE-3da2A:
25.7		 4xiwE-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.92A 4xiwF-3da2A:
25.5		 4xiwF-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 4xiwF-3da2A:
25.5		 4xiwF-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 GLN A  93
HIS A  95
HIS A  97
LEU A 142
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
None
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.01A 4xiwG-3da2A:
25.5		 4xiwG-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 142
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
None
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.50A 4xiwG-3da2A:
25.5		 4xiwG-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 HIS A  97
GLU A 107
LEU A 142
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
None
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.35A 4xiwG-3da2A:
25.5		 4xiwG-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 GLN A  93
HIS A  95
HIS A  97
GLU A 107
LEU A 199
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
 1.05A 4xiwH-3da2A:
25.6		 4xiwH-3da2A:
30.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 4xiwH-3da2A:
25.6		 4xiwH-3da2A:
30.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 ASN A  68
HIS A  95
HIS A  97
HIS A 120
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-3.2A)
 1.43A 4ygfA-3da2A:
26.4		 4ygfA-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 4ygfA-3da2A:
26.4		 4ygfA-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 ASN A  68
HIS A  95
HIS A  97
GLU A 107
HIS A 120
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-3.2A)
 1.29A 4ygfB-3da2A:
26.0		 4ygfB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 ASN A  68
HIS A  97
GLU A 107
VAL A 122
THR A 200
 None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-3.2A)
 0.68A 4ygfB-3da2A:
26.0		 4ygfB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.54A 4ygfB-3da2A:
26.0		 4ygfB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.66A 4ygfB-3da2A:
26.0		 4ygfB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4ygfC-3da2A:
19.9		 4ygfC-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 ASN A  68
HIS A  95
HIS A  97
GLU A 107
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.32A 4ygfD-3da2A:
25.5		 4ygfD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 ASN A  68
HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 4ygfD-3da2A:
25.5		 4ygfD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 4ygfD-3da2A:
25.5		 4ygfD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 11 HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.99A 4ygfD-3da2A:
25.5		 4ygfD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  95
HIS A  97
GLU A 107
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-3.2A)
 1.30A 4ygfE-3da2A:
26.4		 4ygfE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  97
GLU A 107
VAL A 122
THR A 200
 None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-3.2A)
 0.69A 4ygfE-3da2A:
26.4		 4ygfE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 4ygfE-3da2A:
26.4		 4ygfE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.65A 4ygfE-3da2A:
26.4		 4ygfE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 4ygfF-3da2A:
26.2		 4ygfF-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  95
HIS A  97
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.37A 4ygfG-3da2A:
26.1		 4ygfG-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 4ygfG-3da2A:
26.1		 4ygfG-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 4ygfG-3da2A:
26.1		 4ygfG-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.37A 4ygfH-3da2A:
26.1		 4ygfH-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.49A 4yhaA-3da2A:
26.4		 4yhaA-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 10 ASN A  68
HIS A  95
HIS A  97
HIS A 120
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.33A 4yhaB-3da2A:
25.7		 4yhaB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 ASN A  68
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.90A 4yhaB-3da2A:
25.7		 4yhaB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.55A 4yhaB-3da2A:
25.7		 4yhaB-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 4yhaC-3da2A:
26.6		 4yhaC-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 ASN A  68
HIS A  95
HIS A  97
GLU A 107
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-3.2A)
 1.22A 4yhaD-3da2A:
25.4		 4yhaD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 4yhaD-3da2A:
25.4		 4yhaD-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.52A 4yhaE-3da2A:
26.5		 4yhaE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
VAL A 144
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 1.11A 4yhaE-3da2A:
26.5		 4yhaE-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.60A 4yhaF-3da2A:
23.9		 4yhaF-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 4yhaG-3da2A:
26.0		 4yhaG-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 10 ASN A  68
HIS A  95
HIS A  97
GLU A 107
HIS A 120
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 (-3.2A)
 1.23A 4yhaH-3da2A:
26.0		 4yhaH-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.49A 4yhaH-3da2A:
26.0		 4yhaH-3da2A:
28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 GLN A  93
HIS A  95
HIS A  97
GLU A 107
VAL A 122
PHE A 132
LEU A 199
THR A 200
PRO A 203
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.81A 5c8iA-3da2A:
42.3		 5c8iA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		10 / 12 HIS A  95
HIS A  97
GLU A 107
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.45A 5c8iA-3da2A:
42.3		 5c8iA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.92A 5c8iA-3da2A:
42.3		 5c8iA-3da2A:
60.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.91A 5jn8A-3da2A:
32.0		 5jn8A-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 5jn8A-3da2A:
32.0		 5jn8A-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5jn8B-3da2A:
32.2		 5jn8B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.81A 5jn8B-3da2A:
32.2		 5jn8B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 5jn8C-3da2A:
31.8		 5jn8C-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5jn8D-3da2A:
31.5		 5jn8D-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 5jn9A-3da2A:
32.0		 5jn9A-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.86A 5jn9B-3da2A:
32.4		 5jn9B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 5jn9B-3da2A:
32.4		 5jn9B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5jn9C-3da2A:
31.8		 5jn9C-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.94A 5jn9D-3da2A:
31.5		 5jn9D-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 5jn9D-3da2A:
31.5		 5jn9D-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
HIS A  97
GLU A 107
VAL A 144
LEU A 199
 None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
 1.00A 5jnaA-3da2A:
31.9		 5jnaA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
SER A  66
HIS A  97
GLU A 107
LEU A 199
THR A 200
 None
None
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.20A 5jnaA-3da2A:
31.9		 5jnaA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 SER A  66
GLN A  93
HIS A  95
HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.77A 5jnaA-3da2A:
31.9		 5jnaA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 SER A  66
HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.44A 5jnaA-3da2A:
31.9		 5jnaA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 SER A  66
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.05A 5jnaA-3da2A:
31.9		 5jnaA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
SER A  66
HIS A  97
LEU A 199
THR A 200
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.24A 5jnaB-3da2A:
32.2		 5jnaB-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 SER A  66
GLN A  93
HIS A  95
HIS A  97
VAL A 122
VAL A 144
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.77A 5jnaB-3da2A:
32.2		 5jnaB-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 SER A  66
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 5jnaB-3da2A:
32.2		 5jnaB-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 ASN A  68
SER A  66
HIS A  97
LEU A 199
THR A 200
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.24A 5jnaC-3da2A:
31.6		 5jnaC-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 ASN A  68
SER A  66
HIS A  97
VAL A 144
LEU A 199
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
 1.13A 5jnaC-3da2A:
31.6		 5jnaC-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 11 SER A  66
GLN A  93
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.83A 5jnaC-3da2A:
31.6		 5jnaC-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 11 SER A  66
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.47A 5jnaC-3da2A:
31.6		 5jnaC-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
SER A  66
HIS A  97
LEU A 199
THR A 200
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 1.18A 5jnaD-3da2A:
31.5		 5jnaD-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 ASN A  68
SER A  66
HIS A  97
VAL A 144
LEU A 199
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
 1.13A 5jnaD-3da2A:
31.5		 5jnaD-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 SER A  66
GLN A  93
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.81A 5jnaD-3da2A:
31.5		 5jnaD-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 SER A  66
HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5jnaD-3da2A:
31.5		 5jnaD-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 11 HIS A  95
HIS A  97
GLU A 107
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.42A 5jncA-3da2A:
32.0		 5jncA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 11 HIS A  97
GLU A 107
VAL A 122
LEU A 199
THR A 200
 ZN  A 301 ( 3.5A)
ZN  A 301 ( 4.9A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.82A 5jncA-3da2A:
32.0		 5jncA-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.47A 5jncB-3da2A:
32.3		 5jncB-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.43A 5jncC-3da2A:
31.6		 5jncC-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.49A 5jncD-3da2A:
31.5		 5jncD-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.44A 5ku6A-3da2A:
31.9		 5ku6A-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5ku6B-3da2A:
32.3		 5ku6B-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.50A 5ku6C-3da2A:
31.7		 5ku6C-3da2A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.51A 5ku6D-3da2A:
31.5		 5ku6D-3da2A:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 7 HIS A  95
VAL A 122
PHE A 132
LEU A 199
THR A 200
 ZN  A 301 ( 3.6A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.59A 5m78A-3da2A:
42.4		 5m78A-3da2A:
26.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 6 HIS A  95
HIS A 120
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5ogjA-3da2A:
45.6		 5ogjA-3da2A:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 6 HIS A  95
HIS A 120
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.46A 5ogjB-3da2A:
46.3		 5ogjB-3da2A:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 5 HIS A  95
HIS A 120
VAL A 144
LEU A 199
THR A 200
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
 0.49A 5ohhA-3da2A:
45.5		 5ohhA-3da2A:
99.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 6 HIS A  95
HIS A 120
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.45A 5ohhB-3da2A:
45.4		 5ohhB-3da2A:
99.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.42A 5tt3A-3da2A:
26.3		 5tt3A-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.86A 5tt3A-3da2A:
26.3		 5tt3A-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.40A 5tt3B-3da2A:
24.8		 5tt3B-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 10 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.46A 5tt3C-3da2A:
26.5		 5tt3C-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 10 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.83A 5tt3C-3da2A:
26.5		 5tt3C-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.52A 5tt3E-3da2A:
26.3		 5tt3E-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 8 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 5tt3F-3da2A:
25.6		 5tt3F-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 9 HIS A  95
HIS A  97
HIS A 120
VAL A 122
VAL A 144
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.53A 5tt3G-3da2A:
25.6		 5tt3G-3da2A:
28.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 8 HIS A  95
HIS A  97
HIS A 120
VAL A 122
LEU A 199
THR A 200
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
ZN  A 301 ( 3.2A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.48A 5tt3H-3da2A:
25.6		 5tt3H-3da2A:
28.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 HIS A  65
GLN A  93
HIS A  95
HIS A  97
LEU A 199
THR A 200
TRP A 210
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.97A 6bbsA-3da2A:
32.9		 6bbsA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 HIS A  65
GLN A  93
HIS A  97
PHE A 132
LEU A 199
THR A 200
TRP A 210
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.03A 6bbsA-3da2A:
32.9		 6bbsA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A   6
HIS A  65
HIS A  95
HIS A  97
LEU A 199
THR A 200
TRP A 210
 None
None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.69A 6bbsA-3da2A:
32.9		 6bbsA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A   6
HIS A  65
HIS A  97
PHE A 132
LEU A 199
THR A 200
TRP A 210
 None
None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 0.72A 6bbsA-3da2A:
32.9		 6bbsA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		6 / 12 ASN A  68
HIS A  97
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 1.13A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 TRP A   6
GLN A  93
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.85A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 TRP A   6
GLN A  93
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
PRO A 203
 None
4MD  A 401 (-3.1A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.83A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 TRP A   6
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.45A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		8 / 12 TRP A   6
HIS A  97
VAL A 122
PHE A 132
LEU A 199
THR A 200
PRO A 203
TRP A 210
 None
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.33A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 TRP A  17
HIS A  95
HIS A  97
VAL A 122
LEU A 199
THR A 200
TRP A 210
 None
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
None
 1.48A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 5 HIS A  65
GLU A 107
HIS A 120
LEU A 142
VAL A 144
 None
ZN  A 301 ( 4.9A)
ZN  A 301 ( 3.2A)
None
4MD  A 401 ( 4.4A)
 0.29A 6bc9A-3da2A:
42.4		 6bc9A-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		7 / 12 GLN A  93
HIS A  95
HIS A  97
PHE A 132
LEU A 199
THR A 200
PRO A 203
 4MD  A 401 (-3.1A)
ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 (-4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.89A 6bccA-3da2A:
42.4		 6bccA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		9 / 12 HIS A  95
HIS A  97
VAL A 122
PHE A 132
VAL A 144
LEU A 199
THR A 200
PRO A 203
TRP A 210
 ZN  A 301 ( 3.6A)
ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.6A)
4MD  A 401 ( 4.4A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
None
 0.45A 6bccA-3da2A:
42.4		 6bccA-3da2A:
30.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 3da2 CARBONIC ANHYDRASE
13
(Homo
sapiens) 		5 / 12 HIS A  97
VAL A 122
LEU A 199
THR A 200
PRO A 203
 ZN  A 301 ( 3.5A)
4MD  A 401 ( 4.6A)
4MD  A 401 (-4.2A)
4MD  A 401 (-3.2A)
4MD  A 401 ( 4.9A)
 0.93A 6bccA-3da2A:
42.4		 6bccA-3da2A:
30.62