SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4M9'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		3 / 3 GLN A 159
TYR A  74
ARG A  73
 4M9  A  65 ( 3.0A)
None
None
 0.92A 1gtbA-4zblA:
undetectable		 1gtbA-4zblA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		5 / 12 HIS A  62
THR A 162
ILE A 163
PHE A 165
MET A 173
 None
None
4M9  A  65 ( 4.0A)
None
None
 1.44A 1xomB-4zblA:
undetectable		 1xomB-4zblA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		3 / 3 LYS A  68
TYR A 110
PRO A  69
 GOL  A 302 (-3.3A)
4M9  A  65 ( 4.2A)
GOL  A 302 (-4.3A)
 1.13A 2j9cC-4zblA:
undetectable		 2j9cC-4zblA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		5 / 12 ILE A  64
ILE A  18
PHE A 165
PHE A  98
VAL A  22
 4M9  A  65 ( 3.9A)
None
None
None
None
 1.16A 2ygpA-4zblA:
undetectable		 2ygpA-4zblA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		4 / 6 ILE A 163
ARG A  97
MET A 104
THR A 105
 4M9  A  65 ( 4.0A)
None
None
None
 0.90A 3ag1N-4zblA:
undetectable
3ag1W-4zblA:
undetectable		 3ag1N-4zblA:
18.38
3ag1W-4zblA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		4 / 7 ARG A  94
TYR A 110
LEU A  90
TYR A  74
 4M9  A  65 ( 2.7A)
4M9  A  65 ( 4.2A)
None
None
 1.34A 4f8yC-4zblA:
undetectable
4f8yD-4zblA:
undetectable		 4f8yC-4zblA:
20.32
4f8yD-4zblA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RUJ_A_VDXA501_1
(VITAMIN D3 RECEPTOR
A)		 4zbl PHOTOSESITIZER
MKILLERORANGE
(Hydrozoa) 		5 / 12 VAL A  30
ARG A 120
SER A 119
CYH A 116
VAL A  44
 None
None
None
None
4M9  A  65 ( 3.9A)
 1.43A 4rujA-4zblA:
undetectable		 4rujA-4zblA:
19.43