SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4LU'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1J7K_A_ACTA701_0 (HOLLIDAY JUNCTION DNA HELICASE RUVB)	4zad	FDC1 (Candida dubliniensis)	4 / 4	GLY A 190 LEU A 191 GLY A 180 ARG A 179	None 4LU A 603 (-4.1A) None None	1.25A	1j7kA-4zadA: undetectable	1j7kA-4zadA: 22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VQY_A_PARA1201_2 (AAC(6')-IB)	4zad	FDC1 (Candida dubliniensis)	3 / 3	TRP A 163 GLN A 196 TRP A 205	None 4LU A 603 (-3.4A) None	1.09A	2vqyA-4zadA: undetectable	2vqyA-4zadA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_D_TC9D1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zad	FDC1 (Candida dubliniensis)	4 / 8	MET A 99 ILE A 87 ASP A 328 SER A 321	None None None 4LU A 603 ( 3.7A)	1.00A	2xytE-4zadA: undetectable	2xytE-4zadA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zad	FDC1 (Candida dubliniensis)	4 / 8	MET A 99 ILE A 87 ASP A 328 SER A 321	None None None 4LU A 603 ( 3.7A)	1.09A	2xytH-4zadA: undetectable	2xytH-4zadA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_H_TC9H1206_2 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4zad	FDC1 (Candida dubliniensis)	4 / 7	MET A 99 ILE A 87 ASP A 328 SER A 321	None None None 4LU A 603 ( 3.7A)	1.09A	2xytI-4zadA: undetectable	2xytI-4zadA: 20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QZU_C_RTLC201_1 (RETINOL-BINDING PROTEIN 2)	4zad	FDC1 (Candida dubliniensis)	3 / 3	LYS A 404 TRP A 172 GLN A 200	4LU A 603 (-2.6A) None None	1.09A	4qzuC-4zadA: 0.0	4qzuC-4zadA: 14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UIN_H_QI9H1226_0 (FAB 314.3)	4zad	FDC1 (Candida dubliniensis)	5 / 12	HIS A 90 SER A 231 GLY A 221 PHE A 12 GLY A 72	None 4LU A 603 (-2.9A) None None None	1.33A	4uinH-4zadA: undetectable 4uinL-4zadA: undetectable	4uinH-4zadA: 16.41 4uinL-4zadA: 17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5H8T_A_RTLA201_1 (RETINOL-BINDING PROTEIN 1)	4zad	FDC1 (Candida dubliniensis)	4 / 6	LEU A 337 LYS A 404 TRP A 172 GLN A 200	None 4LU A 603 (-2.6A) None None	1.42A	5h8tA-4zadA: undetectable	5h8tA-4zadA: 14.31

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1J7K_A_ACTA701_0","HOLLIDAY JUNCTION DNA HELICASE RUVB","4zad","FDC1","Candida dubliniensis",4,"GLY A 190;LEU A 191;GLY A 180;ARG A 179","None;4LU A 603 (-4.1A);None;None","1.25A","1j7kA-4zadA:undetectable",null],["2VQY_A_PARA1201_2","AAC(6')-IB","4zad","FDC1","Candida dubliniensis",3,"TRP A 163;GLN A 196;TRP A 205","None;4LU A 603 (-3.4A);None","1.09A","2vqyA-4zadA:undetectable","1j7kA-4zadA:22.48"],["2XYT_D_TC9D1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","4zad","FDC1","Candida dubliniensis",4,"MET A  99;ILE A  87;ASP A 328;SER A 321","None;None;None;4LU A 603 ( 3.7A)","1.00A","2xytE-4zadA:undetectable","2vqyA-4zadA:18.43"],["2XYT_G_TC9G1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","4zad","FDC1","Candida dubliniensis",4,"MET A  99;ILE A  87;ASP A 328;SER A 321","None;None;None;4LU A 603 ( 3.7A)","1.09A","2xytH-4zadA:undetectable","2xytE-4zadA:20.63"],["2XYT_H_TC9H1206_2","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","4zad","FDC1","Candida dubliniensis",4,"MET A  99;ILE A  87;ASP A 328;SER A 321","None;None;None;4LU A 603 ( 3.7A)","1.09A","2xytI-4zadA:undetectable","2xytH-4zadA:20.63"],["4QZU_C_RTLC201_1","RETINOL-BINDING PROTEIN 2","4zad","FDC1","Candida dubliniensis",3,"LYS A 404;TRP A 172;GLN A 200","4LU A 603 (-2.6A);None;None","1.09A","4qzuC-4zadA:0.0","2xytI-4zadA:20.63"],["4UIN_H_QI9H1226_0","FAB 314.3","4zad","FDC1","Candida dubliniensis",5,"HIS A  90;SER A 231;GLY A 221;PHE A  12;GLY A  72","None;4LU A 603 (-2.9A);None;None;None","1.33A","4uinH-4zadA:undetectable;4uinL-4zadA:undetectable","4qzuC-4zadA:14.23"],["5H8T_A_RTLA201_1","RETINOL-BINDING PROTEIN 1","4zad","FDC1","Candida dubliniensis",4,"LEU A 337;LYS A 404;TRP A 172;GLN A 200","None;4LU A 603 (-2.6A);None;None","1.42A","5h8tA-4zadA:undetectable","4uinH-4zadA:16.41;4uinL-4zadA:17.43"]]