SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4LD'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
6 / 7 TRP A 374
PRO A 375
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.44A 3u5jA-4z93A:
17.7
3u5jA-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
7 / 8 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.48A 3u5kA-4z93A:
17.8
3u5kA-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
6 / 7 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
0.48A 3u5kB-4z93A:
17.8
3u5kB-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
7 / 8 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.52A 3u5kC-4z93A:
17.4
3u5kC-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
7 / 8 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.59A 3u5kD-4z93A:
17.8
3u5kD-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
4 / 5 VAL A 380
LEU A 385
LEU A 387
ASN A 433
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
0.24A 4a9jA-4z93A:
19.1
4a9jA-4z93A:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
4 / 5 VAL A 380
LEU A 385
LEU A 387
ASN A 433
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
0.23A 4a9jB-4z93A:
19.2
4a9jB-4z93A:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
4 / 5 VAL A 380
LEU A 385
LEU A 387
ASN A 433
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
0.19A 4a9jC-4z93A:
19.2
4a9jC-4z93A:
37.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
5 / 6 VAL A 380
LEU A 385
TYR A 432
ASN A 433
VAL A 439
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 ( 3.9A)
4LD  A 501 (-2.8A)
4LD  A 501 (-3.5A)
0.52A 4a9kA-4z93A:
17.7
4a9kA-4z93A:
36.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
4 / 5 VAL A 380
LEU A 385
ASN A 433
VAL A 439
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-2.8A)
4LD  A 501 (-3.5A)
0.52A 4a9kB-4z93A:
17.8
4a9kB-4z93A:
36.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
7 / 9 TRP A 374
PRO A 375
VAL A 380
LEU A 385
LEU A 387
ASN A 433
MET A 442
4LD  A 501 (-3.9A)
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-2.8A)
4LD  A 501 ( 3.4A)
0.50A 4c66A-4z93A:
17.7
4c66A-4z93A:
36.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
4 / 6 PRO A 375
VAL A 380
TYR A 390
ASN A 433
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 ( 4.0A)
4LD  A 501 (-2.8A)
0.76A 5pbeA-4z93A:
16.8
5pbeA-4z93A:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)
4z93 BROMODOMAIN-CONTAINI
NG PROTEIN 4

(Homo
sapiens)
7 / 8 PRO A 375
VAL A 380
LEU A 385
LEU A 387
CYH A 429
TYR A 432
ASN A 433
4LD  A 501 (-3.9A)
4LD  A 501 ( 3.8A)
4LD  A 501 (-4.1A)
4LD  A 501 (-4.4A)
4LD  A 501 (-3.4A)
4LD  A 501 ( 3.9A)
4LD  A 501 (-2.8A)
0.40A 5y1yA-4z93A:
17.8
5y1yA-4z93A:
38.89