SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4J4'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		5 / 9 ILE C  36
LEU C  41
GLU C  63
VAL C  72
MET C  80
 4J4  C  84 ( 4.3A)
4J4  C  84 ( 4.1A)
None
CA  C 201 ( 4.6A)
4J4  C  84 ( 4.1A)
 1.18A 1ctrA-2n7lC:
8.0		 1ctrA-2n7lC:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CTR_A_TFPA153_1
(CALMODULIN)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		5 / 9 ILE C  36
MET C  60
GLU C  63
VAL C  72
MET C  80
 4J4  C  84 ( 4.3A)
None
None
CA  C 201 ( 4.6A)
4J4  C  84 ( 4.1A)
 1.30A 1ctrA-2n7lC:
8.0		 1ctrA-2n7lC:
39.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA204_1
(CARDIAC TROPONIN C)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		5 / 11 ILE C  36
LEU C  41
MET C  45
LEU C  48
VAL C  64
 4J4  C  84 ( 4.3A)
4J4  C  84 ( 4.1A)
None
None
4J4  C  84 ( 3.7A)
 1.00A 1dtlA-2n7lC:
9.9		 1dtlA-2n7lC:
56.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		5 / 12 ALA C  23
ILE C  26
PHE C  27
MET C  81
LEU C 111
 None
None
None
4J4  C  84 ( 4.7A)
None
 0.92A 1dtlA-2n7lC:
9.9		 1dtlA-2n7lC:
56.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		4 / 8 LEU C  12
PHE C  27
PHE C  77
MET C  81
 None
None
None
4J4  C  84 ( 4.7A)
 0.92A 1wrlC-2n7lC:
8.7
1wrlD-2n7lC:
8.7		 1wrlC-2n7lC:
84.47
1wrlD-2n7lC:
84.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RJD_B_TFPB203_1
(CALMODULIN)		 2n7l TROPONIN C/TROPONIN
I CHIMERA
(Homo
sapiens) 		4 / 7 PHE C  27
LEU C  41
MET C  80
MET C  81
 None
4J4  C  84 ( 4.1A)
4J4  C  84 ( 4.1A)
4J4  C  84 ( 4.7A)
 0.87A 4rjdB-2n7lC:
8.4		 4rjdB-2n7lC:
35.42