SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4GJ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4yt9 PEPTIDYLARGININE
DEIMINASE
(Porphyromonas
gingivalis) 		4 / 7 VAL A 237
TRP A 240
ILE A 251
HIS A 222
 4GJ  A 239 ( 4.9A)
GOL  A 508 (-3.6A)
None
None
 1.20A 4xo7B-4yt9A:
undetectable		 4xo7B-4yt9A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 4yt9 PEPTIDYLARGININE
DEIMINASE
(Porphyromonas
gingivalis) 		5 / 9 VAL A 193
HIS A 223
ILE A 300
LEU A 244
ASP A 238
 None
None
None
None
4GJ  A 351 ( 3.4A)
 1.42A 6c2mC-4yt9A:
undetectable		 6c2mC-4yt9A:
8.52