SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4EB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 9 LEU A 387
ILE A 388
ASN A 391
PHE A 403
LEU A 407
 None
4EB  A1000 ( 4.6A)
4EB  A1000 (-3.5A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
 0.70A 1e7aB-1ysxA:
6.0		 1e7aB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 ASN A 391
CYH A 392
PHE A 403
TYR A 411
VAL A 433
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
None
 0.96A 2bxeB-1ysxA:
6.2		 2bxeB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 ASN A 391
CYH A 392
TYR A 411
VAL A 433
GLY A 434
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 (-3.3A)
None
4EB  A1000 ( 4.7A)
 0.94A 2bxeB-1ysxA:
6.2		 2bxeB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		6 / 12 LEU A 387
ILE A 388
ASN A 391
CYH A 392
PHE A 403
TYR A 411
 None
4EB  A1000 ( 4.6A)
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
 0.99A 2bxeB-1ysxA:
6.2		 2bxeB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 LEU A 387
ILE A 388
CYH A 392
PHE A 403
LYS A 414
 None
4EB  A1000 ( 4.6A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.9A)
 1.08A 2bxeB-1ysxA:
6.2		 2bxeB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXF_A_DZPA2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		6 / 12 ILE A 388
ASN A 391
CYH A 392
PHE A 403
LEU A 407
TYR A 411
 4EB  A1000 ( 4.6A)
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.3A)
 1.03A 2bxfA-1ysxA:
12.8		 2bxfA-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 ILE A 388
ASN A 391
CYH A 392
PHE A 403
TYR A 411
 4EB  A1000 ( 4.6A)
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
 0.81A 2bxfB-1ysxA:
4.8		 2bxfB-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 LEU A 387
ASN A 391
CYH A 392
PHE A 403
TYR A 411
 None
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
 0.93A 2bxfB-1ysxA:
4.8		 2bxfB-1ysxA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		4 / 7 VAL A 418
SER A 470
HIS A 464
THR A 422
 None
4EB  A1000 ( 4.4A)
4EB  A1000 (-2.7A)
4EB  A1000 (-3.9A)
 1.17A 3arrA-1ysxA:
undetectable		 3arrA-1ysxA:
15.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 ASN A 391
CYH A 392
VAL A 433
GLY A 434
LEU A 430
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
None
4EB  A1000 ( 4.7A)
None
 1.39A 4ot2A-1ysxA:
3.8		 4ot2A-1ysxA:
39.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA601_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 ASN A 391
CYH A 392
PHE A 403
LEU A 407
TYR A 411
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.3A)
 1.02A 4po0A-1ysxA:
5.8		 4po0A-1ysxA:
28.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 LEU A 387
ASN A 391
CYH A 392
LEU A 407
TYR A 411
 None
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.3A)
 1.14A 4zbrA-1ysxA:
3.8		 4zbrA-1ysxA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZBR_A_NPSA602_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		6 / 12 LEU A 387
ASN A 391
CYH A 392
PHE A 403
LEU A 407
LYS A 414
 None
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.9A)
 1.00A 4zbrA-1ysxA:
3.8		 4zbrA-1ysxA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DBY_A_NPSA602_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		6 / 12 LEU A 387
ASN A 391
CYH A 392
PHE A 403
LEU A 407
TYR A 411
 None
4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.3A)
 1.11A 5dbyA-1ysxA:
3.8		 5dbyA-1ysxA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DBY_A_NPSA602_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 LEU A 387
CYH A 392
PHE A 403
LEU A 407
LYS A 414
 None
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-4.5A)
4EB  A1000 (-3.9A)
 1.12A 5dbyA-1ysxA:
3.8		 5dbyA-1ysxA:
39.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 CYH A 392
PHE A 403
LYS A 414
LEU A 423
GLY A 434
 4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.9A)
4EB  A1000 (-4.1A)
4EB  A1000 ( 4.7A)
 0.96A 6a7pA-1ysxA:
0.0		 6a7pA-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 PHE A 403
LYS A 414
LEU A 423
GLY A 434
CYH A 437
 4EB  A1000 ( 4.1A)
4EB  A1000 (-3.9A)
4EB  A1000 (-4.1A)
4EB  A1000 ( 4.7A)
4EB  A1000 ( 3.7A)
 1.06A 6a7pA-1ysxA:
0.0		 6a7pA-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		5 / 12 PHE A 403
LYS A 414
VAL A 415
LEU A 423
GLY A 434
 4EB  A1000 ( 4.1A)
4EB  A1000 (-3.9A)
4EB  A1000 (-3.8A)
4EB  A1000 (-4.1A)
4EB  A1000 ( 4.7A)
 0.73A 6a7pA-1ysxA:
0.0		 6a7pA-1ysxA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6A7P_B_9SCB601_1
(SERUM ALBUMIN)		 1ysx SERUM ALBUMIN
(Homo
sapiens) 		4 / 6 ASN A 391
CYH A 392
PHE A 403
TYR A 411
 4EB  A1000 (-3.5A)
4EB  A1000 (-3.2A)
4EB  A1000 ( 4.1A)
4EB  A1000 (-3.3A)
 0.84A 6a7pB-1ysxA:
14.1		 6a7pB-1ysxA:
100.00