SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '476'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 4b2q ATP SYNTHASE SUBUNIT
BETA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 4 ILE D 344
MET D 459
VAL D 165
GLY D 343
 None
None
ADP  D1476 (-4.2A)
None
 1.14A 1e06B-4b2qD:
undetectable		 1e06B-4b2qD:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_A_PPFA410_1
(PHOSPHONOACETATE
HYDROLASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 5 ASP A 304
HIS A 308
HIS A 347
HIS A 435
 ZN  A1475 ( 2.0A)
ZN  A1475 ( 3.2A)
ZN  A1476 ( 3.1A)
ZN  A1475 ( 3.2A)
 0.38A 1ei6A-2x98A:
15.9		 1ei6A-2x98A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 8 ASP A  56
ASP A 304
HIS A 308
HIS A 347
HIS A 435
 ZN  A1476 (-2.2A)
ZN  A1475 ( 2.0A)
ZN  A1475 ( 3.2A)
ZN  A1476 ( 3.1A)
ZN  A1475 ( 3.2A)
 0.46A 1ei6C-2x98A:
15.8		 1ei6C-2x98A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		4 / 8 GLN A 169
ASP A 216
HIS A 241
GLY A  79
 None
None
None
IF6  A1476 (-3.1A)
 0.96A 1ekjA-5g0qA:
undetectable
1ekjB-5g0qA:
undetectable		 1ekjA-5g0qA:
18.95
1ekjB-5g0qA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_X_BRLX504_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		5 / 12 ILE A 454
PHE A 444
GLY A 456
SER A 162
MET A 248
 None
NAP  A 476 (-4.1A)
None
None
None
 1.29A 1fm6X-2euhA:
undetectable		 1fm6X-2euhA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.28A 1k2rA-5fjnA:
undetectable
1k2rB-5fjnA:
undetectable		 1k2rA-5fjnA:
24.55
1k2rB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 1k2rA-5fjnA:
undetectable
1k2rB-5fjnA:
undetectable		 1k2rA-5fjnA:
24.55
1k2rB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 1k2sA-5fjnA:
undetectable
1k2sB-5fjnA:
undetectable		 1k2sA-5fjnA:
24.55
1k2sB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 1k2sA-5fjnA:
undetectable
1k2sB-5fjnA:
undetectable		 1k2sA-5fjnA:
24.55
1k2sB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 1k2uA-5fjnA:
undetectable
1k2uB-5fjnA:
undetectable		 1k2uA-5fjnA:
24.55
1k2uB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 1k2uA-5fjnA:
undetectable
1k2uB-5fjnA:
undetectable		 1k2uA-5fjnA:
24.55
1k2uB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 1lzxA-5fjnA:
undetectable
1lzxB-5fjnA:
undetectable		 1lzxA-5fjnA:
24.55
1lzxB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 1lzxA-5fjnA:
undetectable
1lzxB-5fjnA:
undetectable		 1lzxA-5fjnA:
24.55
1lzxB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 1lzzA-5fjnA:
undetectable
1lzzB-5fjnA:
undetectable		 1lzzA-5fjnA:
24.55
1lzzB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 1m00A-5fjnA:
undetectable
1m00B-5fjnA:
undetectable		 1m00A-5fjnA:
24.55
1m00B-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 1mmwA-5fjnA:
undetectable
1mmwB-5fjnA:
undetectable		 1mmwA-5fjnA:
24.55
1mmwB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 1mmwA-5fjnA:
undetectable
1mmwB-5fjnA:
undetectable		 1mmwA-5fjnA:
24.55
1mmwB-5fjnA:
24.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		6 / 12 GLY A 103
GLY A 329
GLY A 328
HIS A 327
TYR A  84
GLY A 107
 None
None
None
IF6  A1476 (-4.2A)
None
None
 1.25A 1n2xB-5g0qA:
undetectable		 1n2xB-5g0qA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 1om5A-5fjnA:
undetectable
1om5B-5fjnA:
undetectable		 1om5A-5fjnA:
23.52
1om5B-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.29A 1p6hA-5fjnA:
undetectable
1p6hB-5fjnA:
undetectable		 1p6hA-5fjnA:
23.52
1p6hB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 1p6hA-5fjnA:
undetectable
1p6hB-5fjnA:
undetectable		 1p6hA-5fjnA:
23.52
1p6hB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.27A 1p6iA-5fjnA:
undetectable
1p6iB-5fjnA:
undetectable		 1p6iA-5fjnA:
23.52
1p6iB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 1p6iA-5fjnA:
undetectable
1p6iB-5fjnA:
undetectable		 1p6iA-5fjnA:
23.52
1p6iB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 1p6jA-5fjnA:
undetectable
1p6jB-5fjnA:
undetectable		 1p6jA-5fjnA:
23.52
1p6jB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 1p6kA-5fjnA:
undetectable
1p6kB-5fjnA:
undetectable		 1p6kA-5fjnA:
23.52
1p6kB-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QW6_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		3 / 3 ARG A 316
VAL A 438
TRP A 439
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 0.96A 1qw6A-5fjnA:
undetectable		 1qw6A-5fjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		3 / 3 ARG A 316
VAL A 438
TRP A 439
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 0.97A 1qwcA-5fjnA:
undetectable		 1qwcA-5fjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R30_A_SAMA501_0
(BIOTIN SYNTHASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 GLY A 307
ASP A 346
ILE A  54
LEU A 297
VAL A 298
 None
ZN  A1476 (-2.3A)
None
None
None
 1.17A 1r30A-2x98A:
undetectable		 1r30A-2x98A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.72A 1rqjA-4jzxA:
31.0		 1rqjA-4jzxA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.46A 1rqjA-4jzxA:
31.0		 1rqjA-4jzxA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.74A 1rqjB-4jzxA:
31.0		 1rqjB-4jzxA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.45A 1rqjB-4jzxA:
31.0		 1rqjB-4jzxA:
26.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.27A 1rs6A-5fjnA:
undetectable
1rs6B-5fjnA:
undetectable		 1rs6A-5fjnA:
23.52
1rs6B-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 1rs6A-5fjnA:
undetectable
1rs6B-5fjnA:
undetectable		 1rs6A-5fjnA:
23.52
1rs6B-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.26A 1rs7A-5fjnA:
undetectable
1rs7B-5fjnA:
undetectable		 1rs7A-5fjnA:
23.52
1rs7B-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 1rs7A-5fjnA:
undetectable
1rs7B-5fjnA:
undetectable		 1rs7A-5fjnA:
23.52
1rs7B-5fjnA:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 7 MET A 101
ASP A 102
ASP A  99
LYS A 264
 None
CA  A 403 (-2.5A)
None
476  A 402 (-2.9A)
 1.31A 1t03A-4jzxA:
undetectable		 1t03A-4jzxA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		3 / 3 ARG A 316
VAL A 438
TRP A 439
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 0.97A 1vagA-5fjnA:
undetectable		 1vagA-5fjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5mmi 50S RIBOSOMAL
PROTEIN L34,
CHLOROPLASTIC
(Spinacia
oleracea) 		3 / 3 LEU 3 108
HIS 3 112
LYS 3 141
 U  A 697 ( 4.4A)
U  A 476 ( 3.9A)
U  A 476 ( 3.4A)
 0.92A 1y7iA-5mmi3:
undetectable		 1y7iA-5mmi3:
19.29
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.13A 1yhlA-4jzxA:
54.0		 1yhlA-4jzxA:
63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 1yhlA-4jzxA:
54.0		 1yhlA-4jzxA:
63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.44A 1yhlA-4jzxA:
54.0		 1yhlA-4jzxA:
63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 LEU A  95
ARG A 107
THR A 212
TYR A 211
LYS A 264
 None
476  A 402 (-2.9A)
IPE  A 401 ( 4.6A)
None
476  A 402 (-2.9A)
 1.45A 1yq7A-4jzxA:
43.7		 1yq7A-4jzxA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.71A 1yq7A-4jzxA:
43.7		 1yq7A-4jzxA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.53A 1yq7A-4jzxA:
43.7		 1yq7A-4jzxA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.59A 1yv5A-4jzxA:
44.0		 1yv5A-4jzxA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.37A 1yv5A-4jzxA:
44.0		 1yv5A-4jzxA:
37.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		12 / 12 TYR A 107
THR A 109
CYH A 110
PRO A 111
PRO A 134
VAL A 250
TYR A 251
SER A 260
TYR A 263
ILE A 264
VAL A 343
LEU A 347
 HEM  A 476 (-4.0A)
HEM  A 476 (-4.1A)
GSH  A 477 (-3.3A)
HEM  A 476 (-4.2A)
HEM  A 476 (-4.1A)
None
None
None
None
HEM  A 476 (-4.7A)
None
None
 0.31A 1z9hA-2pbjA:
44.7		 1z9hA-2pbjA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		12 / 12 TYR A 107
THR A 109
CYH A 110
PRO A 111
PRO A 134
VAL A 250
TYR A 251
SER A 260
TYR A 263
ILE A 264
VAL A 343
LEU A 347
 HEM  A 476 (-4.0A)
HEM  A 476 (-4.1A)
GSH  A 477 (-3.3A)
HEM  A 476 (-4.2A)
HEM  A 476 (-4.1A)
None
None
None
None
HEM  A 476 (-4.7A)
None
None
 0.31A 1z9hB-2pbjA:
44.7		 1z9hB-2pbjA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		12 / 12 TYR A 107
THR A 109
CYH A 110
PRO A 111
PRO A 134
VAL A 250
TYR A 251
SER A 260
TYR A 263
ILE A 264
VAL A 343
LEU A 347
 HEM  A 476 (-4.0A)
HEM  A 476 (-4.1A)
GSH  A 477 (-3.3A)
HEM  A 476 (-4.2A)
HEM  A 476 (-4.1A)
None
None
None
None
HEM  A 476 (-4.7A)
None
None
 0.31A 1z9hC-2pbjA:
44.6		 1z9hC-2pbjA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		12 / 12 THR A 109
CYH A 110
PRO A 111
PRO A 134
ILE A 246
VAL A 250
TYR A 251
SER A 260
TYR A 263
ILE A 264
VAL A 343
LEU A 347
 HEM  A 476 (-4.1A)
GSH  A 477 (-3.3A)
HEM  A 476 (-4.2A)
HEM  A 476 (-4.1A)
HEM  A 476 ( 3.8A)
None
None
None
None
HEM  A 476 (-4.7A)
None
None
 0.35A 1z9hD-2pbjA:
44.7		 1z9hD-2pbjA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		3 / 3 ARG A 316
VAL A 438
TRP A 439
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 0.93A 1zviA-5fjnA:
undetectable		 1zviA-5fjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.30A 1zvlA-5fjnA:
undetectable
1zvlB-5fjnA:
undetectable		 1zvlA-5fjnA:
23.81
1zvlB-5fjnA:
23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.16A 1zvlA-5fjnA:
undetectable
1zvlB-5fjnA:
undetectable		 1zvlA-5fjnA:
23.81
1zvlB-5fjnA:
23.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.60A 1zw5A-4jzxA:
45.1		 1zw5A-4jzxA:
38.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.42A 1zw5A-4jzxA:
45.1		 1zw5A-4jzxA:
38.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 1zzqA-5fjnA:
undetectable
1zzqB-5fjnA:
undetectable		 1zzqA-5fjnA:
24.30
1zzqB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 0.70A 2e91A-4jzxA:
24.5		 2e91A-4jzxA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
THR A 163
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-4.8A)
 1.38A 2e91A-4jzxA:
24.5		 2e91A-4jzxA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 0.52A 2e91A-4jzxA:
24.5		 2e91A-4jzxA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
THR A 208
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 0.66A 2e91B-4jzxA:
23.7		 2e91B-4jzxA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
THR A 163
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-4.8A)
 1.45A 2e91B-4jzxA:
23.7		 2e91B-4jzxA:
21.64
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.07A 2f89F-4jzxA:
46.2		 2f89F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.29A 2f89F-4jzxA:
46.2		 2f89F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.15A 2f8cF-4jzxA:
45.1		 2f8cF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 LEU A  95
ARG A 107
THR A 212
TYR A 211
LYS A 264
 None
476  A 402 (-2.9A)
IPE  A 401 ( 4.6A)
None
476  A 402 (-2.9A)
 1.42A 2f8cF-4jzxA:
45.1		 2f8cF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.59A 2f8cF-4jzxA:
45.1		 2f8cF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.38A 2f8cF-4jzxA:
45.1		 2f8cF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.16A 2f8zF-4jzxA:
45.8		 2f8zF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.60A 2f8zF-4jzxA:
45.8		 2f8zF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		12 / 12 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
GLN A 167
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.37A 2f94F-4jzxA:
44.8		 2f94F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.16A 2f9kF-4jzxA:
44.9		 2f9kF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 2f9kF-4jzxA:
44.9		 2f9kF-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.42A 2f9kF-4jzxA:
44.9		 2f9kF-4jzxA:
38.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 2g6hA-5fjnA:
undetectable
2g6hB-5fjnA:
undetectable		 2g6hA-5fjnA:
24.30
2g6hB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 2g6hA-5fjnA:
undetectable
2g6hB-5fjnA:
undetectable		 2g6hA-5fjnA:
24.30
2g6hB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 2g6kA-5fjnA:
undetectable
2g6kB-5fjnA:
undetectable		 2g6kA-5fjnA:
24.30
2g6kB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 2g6kA-5fjnA:
undetectable
2g6kB-5fjnA:
undetectable		 2g6kA-5fjnA:
24.30
2g6kB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 2g6mA-5fjnA:
undetectable
2g6mB-5fjnA:
undetectable		 2g6mA-5fjnA:
24.30
2g6mB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 2g6mA-5fjnA:
undetectable
2g6mB-5fjnA:
undetectable		 2g6mA-5fjnA:
24.30
2g6mB-5fjnA:
24.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 2hx3A-5fjnA:
undetectable
2hx3B-5fjnA:
undetectable		 2hx3A-5fjnA:
23.27
2hx3B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.27A 2hx3A-5fjnA:
undetectable
2hx3B-5fjnA:
undetectable		 2hx3A-5fjnA:
23.27
2hx3B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 2hx4A-5fjnA:
undetectable
2hx4B-5fjnA:
undetectable		 2hx4A-5fjnA:
23.27
2hx4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 2hx4A-5fjnA:
undetectable
2hx4B-5fjnA:
undetectable		 2hx4A-5fjnA:
23.27
2hx4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 6 SER A 401
SER A 450
LEU A 405
GLY A 404
 None
None
NAP  A 476 ( 4.7A)
None
 0.98A 2j2pA-2euhA:
undetectable
2j2pC-2euhA:
undetectable		 2j2pA-2euhA:
18.05
2j2pC-2euhA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 6 SER A 401
SER A 450
LEU A 405
GLY A 404
 None
None
NAP  A 476 ( 4.7A)
None
 0.96A 2j2pD-2euhA:
undetectable
2j2pF-2euhA:
undetectable		 2j2pD-2euhA:
18.05
2j2pF-2euhA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
 0.76A 2o1oA-4jzxA:
37.2		 2o1oA-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
 0.53A 2o1oA-4jzxA:
37.2		 2o1oA-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 LEU A  95
ASP A  98
ASP A 102
GLN A 167
THR A 163
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-3.5A)
476  A 402 (-4.8A)
 1.48A 2o1oA-4jzxA:
37.2		 2o1oA-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.75A 2o1oB-4jzxA:
37.7		 2o1oB-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
 0.64A 2o1oB-4jzxA:
37.7		 2o1oB-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4N_A_TPVA300_2
(PROTEASE)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 8 LEU A 148
ILE A 247
GLY A 235
ILE A 234
 None
None
None
NAP  A 476 (-3.8A)
 0.66A 2o4nB-2euhA:
undetectable		 2o4nB-2euhA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ASP A 102
GLN A 167
GLN A 247
ASP A 251
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
None
 0.84A 2q58A-4jzxA:
36.9		 2q58A-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ASP A 102
LYS A 207
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 1.48A 2q58A-4jzxA:
36.9		 2q58A-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 251
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
None
 0.82A 2q58A-4jzxA:
36.9		 2q58A-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.79A 2q58B-4jzxA:
37.1		 2q58B-4jzxA:
25.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
 0.65A 2q58B-4jzxA:
37.1		 2q58B-4jzxA:
25.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.14A 2qisA-4jzxA:
44.5		 2qisA-4jzxA:
36.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.62A 2qisA-4jzxA:
44.5		 2qisA-4jzxA:
36.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 9 ILE A 215
VAL A  63
CYH A  67
LYS A  68
 FAD  A 476 (-4.6A)
None
None
None
 0.94A 2vufB-3pm9A:
undetectable		 2vufB-3pm9A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 12 ILE A 468
ASN A 470
GLY A 214
GLY A 211
LEU A 181
 None
FAD  A 476 (-4.0A)
None
FAD  A 476 (-3.2A)
None
 0.98A 2zw9A-3pm9A:
undetectable		 2zw9A-3pm9A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AF0_A_PAUA314_0
(PANTOTHENATE KINASE)		 1x9q 4M5.3
ANTI-FLUORESCEIN
SINGLE CHAIN
ANTIBODY FRAGMENT
(Homo
sapiens) 		5 / 8 ASP A 101
LEU A  56
LYS A  58
GLY A 103
TYR A 105
 ACT  A1476 (-4.1A)
None
ACT  A1476 (-3.0A)
None
None
 1.50A 3af0A-1x9qA:
undetectable		 3af0A-1x9qA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 3b3mA-5fjnA:
undetectable
3b3mB-5fjnA:
undetectable		 3b3mA-5fjnA:
23.27
3b3mB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3b3mA-5fjnA:
undetectable
3b3mB-5fjnA:
undetectable		 3b3mA-5fjnA:
23.27
3b3mB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 3b3nA-5fjnA:
undetectable
3b3nB-5fjnA:
undetectable		 3b3nA-5fjnA:
23.27
3b3nB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3b3oA-5fjnA:
undetectable
3b3oB-5fjnA:
undetectable		 3b3oA-5fjnA:
23.27
3b3oB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 3b3pA-5fjnA:
undetectable
3b3pB-5fjnA:
undetectable		 3b3pA-5fjnA:
23.27
3b3pB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_B_SHHB301_1
(HISTONE DEACETYLASE
7A)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 8 HIS A 435
HIS A 308
ASP A  56
GLY A  57
 ZN  A1475 ( 3.2A)
ZN  A1475 ( 3.2A)
ZN  A1476 (-2.2A)
None
 0.87A 3c0zB-2x98A:
undetectable		 3c0zB-2x98A:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.26A 3dqrA-5fjnA:
undetectable
3dqrB-5fjnA:
undetectable		 3dqrA-5fjnA:
23.54
3dqrB-5fjnA:
23.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.08A 3ez3A-4jzxA:
44.6		 3ez3A-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.83A 3ez3A-4jzxA:
44.6		 3ez3A-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.60A 3ez3A-4jzxA:
44.6		 3ez3A-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.06A 3ez3B-4jzxA:
44.0		 3ez3B-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.71A 3ez3B-4jzxA:
44.0		 3ez3B-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.49A 3ez3B-4jzxA:
44.0		 3ez3B-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.05A 3ez3C-4jzxA:
44.6		 3ez3C-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.74A 3ez3C-4jzxA:
44.6		 3ez3C-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.62A 3ez3C-4jzxA:
44.6		 3ez3C-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.13A 3ez3D-4jzxA:
43.7		 3ez3D-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.72A 3ez3D-4jzxA:
43.7		 3ez3D-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.46A 3ez3D-4jzxA:
43.7		 3ez3D-4jzxA:
33.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.29A 3fc5A-5fjnA:
undetectable
3fc5B-5fjnA:
undetectable		 3fc5A-5fjnA:
23.46
3fc5B-5fjnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 3fc5A-5fjnA:
undetectable
3fc5B-5fjnA:
undetectable		 3fc5A-5fjnA:
23.46
3fc5B-5fjnA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 7 GLY A 345
HIS A 347
ASP A  56
GLN A  62
 None
ZN  A1476 ( 3.1A)
ZN  A1476 (-2.2A)
None
 0.93A 3fi0P-2x98A:
undetectable		 3fi0P-2x98A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN0_A_DMOA551_1
(ARGINASE-1)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		5 / 9 HIS A 359
ASP A 386
HIS A 388
ASP A 255
GLU A 280
 MG  A 476 ( 4.5A)
None
CO3  A 477 (-4.0A)
MG  A 476 (-2.8A)
MG  A 476 (-3.3A)
 1.49A 3gn0A-3nxlA:
undetectable		 3gn0A-3nxlA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3hsoA-5fjnA:
undetectable
3hsoB-5fjnA:
undetectable		 3hsoA-5fjnA:
23.27
3hsoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 3hspA-5fjnA:
undetectable
3hspB-5fjnA:
undetectable		 3hspA-5fjnA:
23.27
3hspB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 3hspA-5fjnA:
undetectable
3hspB-5fjnA:
undetectable		 3hspA-5fjnA:
23.27
3hspB-5fjnA:
23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 10 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.74A 3ibaA-4jzxA:
53.8		 3ibaA-4jzxA:
63.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.50A 3ibaA-4jzxA:
53.8		 3ibaA-4jzxA:
63.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3jt3A-5fjnA:
undetectable
3jt3B-5fjnA:
undetectable		 3jt3A-5fjnA:
23.27
3jt3B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 3jt4A-5fjnA:
undetectable
3jt4B-5fjnA:
undetectable		 3jt4A-5fjnA:
23.27
3jt4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3jt4A-5fjnA:
undetectable
3jt4B-5fjnA:
undetectable		 3jt4A-5fjnA:
23.27
3jt4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 3jt5A-5fjnA:
undetectable
3jt5B-5fjnA:
undetectable		 3jt5A-5fjnA:
23.27
3jt5B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 3jt6A-5fjnA:
undetectable
3jt6B-5fjnA:
undetectable		 3jt6A-5fjnA:
23.27
3jt6B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 3jt6A-5fjnA:
undetectable
3jt6B-5fjnA:
undetectable		 3jt6A-5fjnA:
23.27
3jt6B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 3jt7A-5fjnA:
undetectable
3jt7B-5fjnA:
undetectable		 3jt7A-5fjnA:
23.27
3jt7B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3jt7A-5fjnA:
undetectable
3jt7B-5fjnA:
undetectable		 3jt7A-5fjnA:
23.27
3jt7B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 3jt9A-5fjnA:
undetectable
3jt9B-5fjnA:
undetectable		 3jt9A-5fjnA:
23.27
3jt9B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3jt9A-5fjnA:
undetectable
3jt9B-5fjnA:
undetectable		 3jt9A-5fjnA:
23.27
3jt9B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 3jtaA-5fjnA:
undetectable
3jtaB-5fjnA:
undetectable		 3jtaA-5fjnA:
23.27
3jtaB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3jtaA-5fjnA:
undetectable
3jtaB-5fjnA:
undetectable		 3jtaA-5fjnA:
23.27
3jtaB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.39A 3jwtA-5fjnA:
undetectable
3jwtB-5fjnA:
undetectable		 3jwtA-5fjnA:
23.27
3jwtB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 3jx0A-5fjnA:
undetectable
3jx0B-5fjnA:
undetectable		 3jx0A-5fjnA:
23.27
3jx0B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.41A 3jx1A-5fjnA:
undetectable
3jx1B-5fjnA:
undetectable		 3jx1A-5fjnA:
23.27
3jx1B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.39A 3jx1A-5fjnA:
undetectable
3jx1B-5fjnA:
undetectable		 3jx1A-5fjnA:
23.27
3jx1B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 3jx4A-5fjnA:
undetectable
3jx4B-5fjnA:
undetectable		 3jx4A-5fjnA:
23.54
3jx4B-5fjnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.27A 3jx5A-5fjnA:
undetectable
3jx5B-5fjnA:
undetectable		 3jx5A-5fjnA:
23.54
3jx5B-5fjnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 6 ARG A 437
SER A 162
GLY A 230
GLU A 236
 NAP  A 476 (-4.5A)
None
NAP  A 476 (-3.1A)
None
 1.11A 3k9fA-2euhA:
undetectable
3k9fB-2euhA:
undetectable
3k9fD-2euhA:
2.0		 3k9fA-2euhA:
23.48
3k9fB-2euhA:
23.48
3k9fD-2euhA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		5 / 12 TYR A 107
PHE A 261
PHE A 270
GLY A 282
ILE A 140
 HEM  A 476 (-4.0A)
None
None
None
None
 1.20A 3ld6A-2pbjA:
undetectable		 3ld6A-2pbjA:
21.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.05A 3ldwA-4jzxA:
44.6		 3ldwA-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.86A 3ldwA-4jzxA:
44.6		 3ldwA-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.62A 3ldwA-4jzxA:
44.6		 3ldwA-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 3ldwB-4jzxA:
44.0		 3ldwB-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.73A 3ldwB-4jzxA:
44.0		 3ldwB-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.51A 3ldwB-4jzxA:
44.0		 3ldwB-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.83A 3ldwC-4jzxA:
44.5		 3ldwC-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.60A 3ldwC-4jzxA:
44.5		 3ldwC-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.14A 3ldwD-4jzxA:
43.7		 3ldwD-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.72A 3ldwD-4jzxA:
43.7		 3ldwD-4jzxA:
33.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.50A 3ldwD-4jzxA:
43.7		 3ldwD-4jzxA:
33.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3n2rA-5fjnA:
undetectable
3n2rB-5fjnA:
undetectable		 3n2rA-5fjnA:
23.27
3n2rB-5fjnA:
23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 3n45F-4jzxA:
45.1		 3n45F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 LEU A  95
ARG A 107
THR A 212
TYR A 211
LYS A 264
 None
476  A 402 (-2.9A)
IPE  A 401 ( 4.6A)
None
476  A 402 (-2.9A)
 1.48A 3n45F-4jzxA:
45.1		 3n45F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.64A 3n45F-4jzxA:
45.1		 3n45F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.42A 3n45F-4jzxA:
45.1		 3n45F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.14A 3n46F-4jzxA:
44.8		 3n46F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.64A 3n46F-4jzxA:
44.8		 3n46F-4jzxA:
38.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.40A 3n46F-4jzxA:
44.8		 3n46F-4jzxA:
38.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3n5vA-5fjnA:
undetectable
3n5vB-5fjnA:
undetectable		 3n5vA-5fjnA:
23.27
3n5vB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3n5yA-5fjnA:
undetectable
3n5yB-5fjnA:
undetectable		 3n5yA-5fjnA:
23.27
3n5yB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3n5zA-5fjnA:
undetectable
3n5zB-5fjnA:
undetectable		 3n5zA-5fjnA:
23.27
3n5zB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.39A 3nlmA-5fjnA:
undetectable
3nlmB-5fjnA:
undetectable		 3nlmA-5fjnA:
23.27
3nlmB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 3nlnA-5fjnA:
undetectable
3nlnB-5fjnA:
undetectable		 3nlnA-5fjnA:
23.27
3nlnB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.36A 3nloA-5fjnA:
undetectable
3nloB-5fjnA:
undetectable		 3nloA-5fjnA:
23.27
3nloB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 3nloA-5fjnA:
undetectable
3nloB-5fjnA:
undetectable		 3nloA-5fjnA:
23.27
3nloB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 3nlpA-5fjnA:
undetectable
3nlpB-5fjnA:
undetectable		 3nlpA-5fjnA:
23.54
3nlpB-5fjnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3nlvA-5fjnA:
undetectable
3nlvB-5fjnA:
undetectable		 3nlvA-5fjnA:
23.27
3nlvB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3nlwA-5fjnA:
undetectable
3nlwB-5fjnA:
undetectable		 3nlwA-5fjnA:
23.27
3nlwB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.38A 3nlzA-5fjnA:
undetectable
3nlzB-5fjnA:
undetectable		 3nlzA-5fjnA:
23.27
3nlzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 3nnzA-5fjnA:
undetectable
3nnzB-5fjnA:
undetectable		 3nnzA-5fjnA:
23.27
3nnzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.39A 3pneA-5fjnA:
undetectable
3pneB-5fjnA:
undetectable		 3pneA-5fjnA:
23.27
3pneB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.38A 3pnfA-5fjnA:
undetectable
3pnfB-5fjnA:
undetectable		 3pnfA-5fjnA:
23.27
3pnfB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.42A 3pngA-5fjnA:
undetectable
3pngB-5fjnA:
undetectable		 3pngA-5fjnA:
23.27
3pngB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.41A 3pngA-5fjnA:
undetectable
3pngB-5fjnA:
undetectable		 3pngA-5fjnA:
23.27
3pngB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 3q99A-5fjnA:
undetectable
3q99B-5fjnA:
undetectable		 3q99A-5fjnA:
23.27
3q99B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.29A 3q9aA-5fjnA:
undetectable
3q9aB-5fjnA:
undetectable		 3q9aA-5fjnA:
23.27
3q9aB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 3q9aA-5fjnA:
undetectable
3q9aB-5fjnA:
undetectable		 3q9aA-5fjnA:
23.27
3q9aB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.40A 3rqjA-5fjnA:
undetectable
3rqjB-5fjnA:
undetectable		 3rqjA-5fjnA:
23.27
3rqjB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.36A 3rqjA-5fjnA:
undetectable
3rqjB-5fjnA:
undetectable		 3rqjA-5fjnA:
23.27
3rqjB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.41A 3rqkA-5fjnA:
undetectable
3rqkB-5fjnA:
undetectable		 3rqkA-5fjnA:
23.27
3rqkB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.39A 3rqmA-5fjnA:
undetectable
3rqmB-5fjnA:
undetectable		 3rqmA-5fjnA:
23.27
3rqmB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.43A 3rqnA-5fjnA:
undetectable
3rqnB-5fjnA:
undetectable		 3rqnA-5fjnA:
23.27
3rqnB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		3 / 3 HIS A 359
SER A 367
ASN A 362
 MG  A 476 ( 4.5A)
None
CO3  A 477 ( 4.8A)
 0.90A 3s8pB-3nxlA:
0.0		 3s8pB-3nxlA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.38A 3svpA-5fjnA:
undetectable
3svpB-5fjnA:
undetectable		 3svpA-5fjnA:
23.27
3svpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.37A 3svpA-5fjnA:
undetectable
3svpB-5fjnA:
undetectable		 3svpA-5fjnA:
23.27
3svpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 3svqA-5fjnA:
undetectable
3svqB-5fjnA:
undetectable		 3svqA-5fjnA:
23.27
3svqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 3svqA-5fjnA:
undetectable
3svqB-5fjnA:
undetectable		 3svqA-5fjnA:
23.27
3svqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3tylA-5fjnA:
undetectable
3tylB-5fjnA:
undetectable		 3tylA-5fjnA:
23.27
3tylB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3tymA-5fjnA:
undetectable
3tymB-5fjnA:
undetectable		 3tymA-5fjnA:
23.27
3tymB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 3tynA-5fjnA:
undetectable
3tynB-5fjnA:
undetectable		 3tynA-5fjnA:
23.27
3tynB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 3tyoA-5fjnA:
undetectable
3tyoB-5fjnA:
undetectable		 3tyoA-5fjnA:
23.27
3tyoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 3ufoA-5fjnA:
undetectable
3ufoB-5fjnA:
undetectable		 3ufoA-5fjnA:
23.27
3ufoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 3ufqA-5fjnA:
undetectable
3ufqB-5fjnA:
undetectable		 3ufqA-5fjnA:
23.27
3ufqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 3uftA-5fjnA:
undetectable
3uftB-5fjnA:
undetectable		 3uftA-5fjnA:
23.27
3uftB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.40A 3uftA-5fjnA:
undetectable
3uftB-5fjnA:
undetectable		 3uftA-5fjnA:
23.27
3uftB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.37A 3ufuA-5fjnA:
undetectable
3ufuB-5fjnA:
undetectable		 3ufuA-5fjnA:
23.27
3ufuB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 3ufvA-5fjnA:
undetectable
3ufvB-5fjnA:
undetectable		 3ufvA-5fjnA:
23.27
3ufvB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.37A 3ufwA-5fjnA:
undetectable
3ufwB-5fjnA:
undetectable		 3ufwA-5fjnA:
23.27
3ufwB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 4a5p PROTEIN MXIA
(Shigella
flexneri) 		5 / 12 TYR A 483
LEU A 486
SER A 477
PHE A 428
PHE A 367
 None
None
MLY  A 476 ( 4.9A)
None
None
 1.49A 3ugrA-4a5pA:
undetectable		 3ugrA-4a5pA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		3 / 3 LYS A 264
ARG A  51
LEU A  95
 476  A 402 (-2.9A)
IPE  A 401 (-2.8A)
None
 1.42A 3v4tE-4jzxA:
undetectable		 3v4tE-4jzxA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 9 ILE A 468
MET A 469
LEU A  77
ILE A  99
ILE A 215
 None
None
None
None
FAD  A 476 (-4.6A)
 1.07A 3zosA-3pm9A:
undetectable		 3zosA-3pm9A:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4c39A-5fjnA:
undetectable
4c39B-5fjnA:
undetectable		 4c39A-5fjnA:
23.27
4c39B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 4canA-5fjnA:
undetectable
4canB-5fjnA:
undetectable		 4canA-5fjnA:
23.27
4canB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4caoA-5fjnA:
undetectable
4caoB-5fjnA:
undetectable		 4caoA-5fjnA:
23.27
4caoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4capA-5fjnA:
undetectable
4capB-5fjnA:
undetectable		 4capA-5fjnA:
23.27
4capB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4caqA-5fjnA:
undetectable
4caqB-5fjnA:
undetectable		 4caqA-5fjnA:
23.27
4caqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4caqA-5fjnA:
undetectable
4caqB-5fjnA:
undetectable		 4caqA-5fjnA:
23.27
4caqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4ctpA-5fjnA:
undetectable
4ctpB-5fjnA:
undetectable		 4ctpA-5fjnA:
23.27
4ctpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4ctrA-5fjnA:
undetectable
4ctrB-5fjnA:
undetectable		 4ctrA-5fjnA:
23.27
4ctrB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4cttA-5fjnA:
undetectable
4cttB-5fjnA:
undetectable		 4cttA-5fjnA:
23.27
4cttB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4ctuA-5fjnA:
undetectable
4ctuB-5fjnA:
undetectable		 4ctuA-5fjnA:
23.27
4ctuB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 4ctwA-5fjnA:
undetectable
4ctwB-5fjnA:
undetectable		 4ctwA-5fjnA:
23.27
4ctwB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.39A 4ctxA-5fjnA:
undetectable
4ctxB-5fjnA:
undetectable		 4ctxA-5fjnA:
23.27
4ctxB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.37A 4ctxA-5fjnA:
undetectable
4ctxB-5fjnA:
undetectable		 4ctxA-5fjnA:
23.27
4ctxB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4cx4A-5fjnA:
undetectable
4cx4B-5fjnA:
undetectable		 4cx4A-5fjnA:
23.54
4cx4B-5fjnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.37A 4cx5A-5fjnA:
undetectable
4cx5B-5fjnA:
undetectable		 4cx5A-5fjnA:
23.27
4cx5B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 4cx6A-5fjnA:
undetectable
4cx6B-5fjnA:
undetectable		 4cx6A-5fjnA:
23.27
4cx6B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4cx6A-5fjnA:
undetectable
4cx6B-5fjnA:
undetectable		 4cx6A-5fjnA:
23.27
4cx6B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4d1nA-5fjnA:
undetectable
4d1nB-5fjnA:
undetectable		 4d1nA-5fjnA:
23.09
4d1nB-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4d1nA-5fjnA:
undetectable
4d1nB-5fjnA:
undetectable		 4d1nA-5fjnA:
23.09
4d1nB-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4d1nC-5fjnA:
undetectable
4d1nD-5fjnA:
undetectable		 4d1nC-5fjnA:
23.09
4d1nD-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4d2yA-5fjnA:
undetectable
4d2yB-5fjnA:
undetectable		 4d2yA-5fjnA:
23.27
4d2yB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4d2yA-5fjnA:
undetectable
4d2yB-5fjnA:
undetectable		 4d2yA-5fjnA:
23.27
4d2yB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4d2zA-5fjnA:
undetectable
4d2zB-5fjnA:
undetectable		 4d2zA-5fjnA:
23.27
4d2zB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4d30A-5fjnA:
undetectable
4d30B-5fjnA:
undetectable		 4d30A-5fjnA:
23.27
4d30B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4d30A-5fjnA:
undetectable
4d30B-5fjnA:
undetectable		 4d30A-5fjnA:
23.27
4d30B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4d31A-5fjnA:
undetectable
4d31B-5fjnA:
undetectable		 4d31A-5fjnA:
23.27
4d31B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4d32A-5fjnA:
undetectable
4d32B-5fjnA:
undetectable		 4d32A-5fjnA:
23.27
4d32B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4d32A-5fjnA:
undetectable
4d32B-5fjnA:
undetectable		 4d32A-5fjnA:
23.27
4d32B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4d3bA-5fjnA:
undetectable
4d3bB-5fjnA:
undetectable		 4d3bA-5fjnA:
23.27
4d3bB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4d3bA-5fjnA:
undetectable
4d3bB-5fjnA:
undetectable		 4d3bA-5fjnA:
23.27
4d3bB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4d7oA-5fjnA:
undetectable
4d7oB-5fjnA:
undetectable		 4d7oA-5fjnA:
23.27
4d7oB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4d7oA-5fjnA:
undetectable
4d7oB-5fjnA:
undetectable		 4d7oA-5fjnA:
23.27
4d7oB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_B_BEZB1000_0
(BENZOATE-COENZYME A
LIGASE)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		5 / 9 ALA A 452
GLY A 230
ILE A 234
GLY A 235
ILE A 238
 None
NAP  A 476 (-3.1A)
NAP  A 476 (-3.8A)
None
None
 1.12A 4eatB-2euhA:
2.6		 4eatB-2euhA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.36A 4euxA-5fjnA:
undetectable
4euxB-5fjnA:
undetectable		 4euxA-5fjnA:
23.27
4euxB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4euxA-5fjnA:
undetectable
4euxB-5fjnA:
undetectable		 4euxA-5fjnA:
23.27
4euxB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		4 / 5 GLY A  88
GLY A  89
ASN A 470
GLU A  42
 None
FAD  A 476 (-3.7A)
FAD  A 476 (-4.0A)
None
 1.16A 4fglC-3pm9A:
undetectable		 4fglC-3pm9A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4fvyA-5fjnA:
undetectable
4fvyB-5fjnA:
undetectable		 4fvyA-5fjnA:
23.27
4fvyB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4fvyA-5fjnA:
undetectable
4fvyB-5fjnA:
undetectable		 4fvyA-5fjnA:
23.27
4fvyB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.25A 4fvzA-5fjnA:
undetectable
4fvzB-5fjnA:
undetectable		 4fvzA-5fjnA:
23.27
4fvzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4fvzA-5fjnA:
undetectable
4fvzB-5fjnA:
undetectable		 4fvzA-5fjnA:
23.27
4fvzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4fw0A-5fjnA:
undetectable
4fw0B-5fjnA:
undetectable		 4fw0A-5fjnA:
23.27
4fw0B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4fw0A-5fjnA:
undetectable
4fw0B-5fjnA:
undetectable		 4fw0A-5fjnA:
23.27
4fw0B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 2pbj PROSTAGLANDIN E
SYNTHASE 2
(Macaca
fascicularis) 		3 / 3 PRO A 134
TYR A 107
GLY A 268
 HEM  A 476 (-4.1A)
HEM  A 476 (-4.0A)
None
 0.71A 4g2zA-2pbjA:
undetectable		 4g2zA-2pbjA:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.20A 4hvcB-5g0qA:
undetectable		 4hvcB-5g0qA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4b2q ATP SYNTHASE SUBUNIT
BETA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 5 PRO D 350
ASP D 349
ILE D 344
VAL D 161
 None
None
None
ADP  D1476 (-4.4A)
 1.14A 4hytA-4b2qD:
undetectable		 4hytA-4b2qD:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4imtA-5fjnA:
undetectable
4imtB-5fjnA:
undetectable		 4imtA-5fjnA:
23.27
4imtB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4imtA-5fjnA:
undetectable
4imtB-5fjnA:
undetectable		 4imtA-5fjnA:
23.27
4imtB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA805_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4imwA-5fjnA:
undetectable
4imwB-5fjnA:
undetectable		 4imwA-5fjnA:
23.27
4imwB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4jsfA-5fjnA:
undetectable
4jsfB-5fjnA:
undetectable		 4jsfA-5fjnA:
23.27
4jsfB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 4jsgA-5fjnA:
undetectable
4jsgB-5fjnA:
undetectable		 4jsgA-5fjnA:
23.27
4jsgB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.36A 4jshA-5fjnA:
undetectable
4jshB-5fjnA:
undetectable		 4jshA-5fjnA:
23.27
4jshB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4jsiA-5fjnA:
undetectable
4jsiB-5fjnA:
undetectable		 4jsiA-5fjnA:
23.27
4jsiB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4jsjA-5fjnA:
undetectable
4jsjB-5fjnA:
undetectable		 4jsjA-5fjnA:
23.27
4jsjB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4k5dA-5fjnA:
undetectable
4k5dB-5fjnA:
undetectable		 4k5dA-5fjnA:
23.27
4k5dB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4k5dA-5fjnA:
undetectable
4k5dB-5fjnA:
undetectable		 4k5dA-5fjnA:
23.27
4k5dB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4k5eA-5fjnA:
undetectable
4k5eB-5fjnA:
undetectable		 4k5eA-5fjnA:
23.27
4k5eB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 4k5fA-5fjnA:
undetectable
4k5fB-5fjnA:
undetectable		 4k5fA-5fjnA:
23.27
4k5fB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4k5fA-5fjnA:
undetectable
4k5fB-5fjnA:
undetectable		 4k5fA-5fjnA:
23.27
4k5fB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 4k5gA-5fjnA:
undetectable
4k5gB-5fjnA:
undetectable		 4k5gA-5fjnA:
23.27
4k5gB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 4kchA-5fjnA:
undetectable
4kchB-5fjnA:
undetectable		 4kchA-5fjnA:
23.27
4kchB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4kchA-5fjnA:
undetectable
4kchB-5fjnA:
undetectable		 4kchA-5fjnA:
23.27
4kchB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4kciA-5fjnA:
undetectable
4kciB-5fjnA:
undetectable		 4kciA-5fjnA:
23.27
4kciB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4kciA-5fjnA:
undetectable
4kciB-5fjnA:
undetectable		 4kciA-5fjnA:
23.27
4kciB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4kcjA-5fjnA:
undetectable
4kcjB-5fjnA:
undetectable		 4kcjA-5fjnA:
23.27
4kcjB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4kcjA-5fjnA:
undetectable
4kcjB-5fjnA:
undetectable		 4kcjA-5fjnA:
23.27
4kcjB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4kclA-5fjnA:
undetectable
4kclB-5fjnA:
undetectable		 4kclA-5fjnA:
23.27
4kclB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4kcmA-5fjnA:
undetectable
4kcmB-5fjnA:
undetectable		 4kcmA-5fjnA:
23.27
4kcmB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 6 GLU A 100
ARG A 103
ASP A 440
ARG A 437
 None
None
None
NAP  A 476 (-4.5A)
 1.16A 4kcnA-2euhA:
undetectable		 4kcnA-2euhA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		4 / 6 GLU A 100
ARG A 103
ASP A 440
ARG A 437
 None
None
None
NAP  A 476 (-4.5A)
 1.11A 4kcnB-2euhA:
undetectable		 4kcnB-2euhA:
22.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.11A 4kfaA-4jzxA:
43.9		 4kfaA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.66A 4kfaA-4jzxA:
43.9		 4kfaA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 4kpdA-4jzxA:
45.3		 4kpdA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 4kpdA-4jzxA:
45.3		 4kpdA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.37A 4kpdA-4jzxA:
45.3		 4kpdA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 4kpjA-4jzxA:
43.9		 4kpjA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.43A 4kpjA-4jzxA:
43.9		 4kpjA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.11A 4kq5A-4jzxA:
44.3		 4kq5A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.68A 4kq5A-4jzxA:
44.3		 4kq5A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.47A 4kq5A-4jzxA:
44.3		 4kq5A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 4kqsA-4jzxA:
45.0		 4kqsA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.62A 4kqsA-4jzxA:
45.0		 4kqsA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.40A 4kqsA-4jzxA:
45.0		 4kqsA-4jzxA:
36.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_A_SHHA407_1
(HISTONE DEACETYLASE
2)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 ASP A 433
HIS A 347
HIS A 435
GLY A 434
ASP A  56
 MG  A1480 (-2.4A)
ZN  A1476 ( 3.1A)
ZN  A1475 ( 3.2A)
None
ZN  A1476 (-2.2A)
 1.01A 4lxzA-2x98A:
3.0		 4lxzA-2x98A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 ASP A 433
HIS A 347
HIS A 435
GLY A 434
ASP A  56
 MG  A1480 (-2.4A)
ZN  A1476 ( 3.1A)
ZN  A1475 ( 3.2A)
None
ZN  A1476 (-2.2A)
 1.03A 4lxzC-2x98A:
3.2		 4lxzC-2x98A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LXZ_C_SHHC406_1
(HISTONE DEACETYLASE
2)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 HIS A 435
HIS A 308
GLY A 307
ASP A  56
GLY A  57
 ZN  A1475 ( 3.2A)
ZN  A1475 ( 3.2A)
None
ZN  A1476 (-2.2A)
None
 1.21A 4lxzC-2x98A:
3.2		 4lxzC-2x98A:
20.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.11A 4n9uA-4jzxA:
44.1		 4n9uA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 4n9uA-4jzxA:
44.1		 4n9uA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.46A 4n9uA-4jzxA:
44.1		 4n9uA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 208
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 ( 3.4A)
 1.34A 4n9uA-4jzxA:
44.1		 4n9uA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 12 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.11A 4ng6A-4jzxA:
45.3		 4ng6A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		11 / 12 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
GLN A 167
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-3.5A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.41A 4ng6A-4jzxA:
45.3		 4ng6A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.74A 4nkeA-4jzxA:
44.2		 4nkeA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.60A 4nkeA-4jzxA:
44.2		 4nkeA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 LEU A  95
ASP A  98
ASP A 102
GLN A 167
THR A 163
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-3.5A)
476  A 402 (-4.8A)
 1.49A 4nkeA-4jzxA:
44.2		 4nkeA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.09A 4nkfA-4jzxA:
44.2		 4nkfA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.47A 4nkfA-4jzxA:
44.2		 4nkfA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.31A 4nuaA-4jzxA:
44.3		 4nuaA-4jzxA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.79A 4nuaA-4jzxA:
44.3		 4nuaA-4jzxA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.66A 4nuaA-4jzxA:
44.3		 4nuaA-4jzxA:
36.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.09A 4oguA-4jzxA:
44.1		 4oguA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.40A 4oguA-4jzxA:
44.1		 4oguA-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.14A 4p0vA-4jzxA:
45.6		 4p0vA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 4p0vA-4jzxA:
45.6		 4p0vA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		8 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.45A 4p0vA-4jzxA:
45.6		 4p0vA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.10A 4p0wA-4jzxA:
45.6		 4p0wA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 11 LEU A  95
ARG A 107
THR A 212
TYR A 211
LYS A 264
 None
476  A 402 (-2.9A)
IPE  A 401 ( 4.6A)
None
476  A 402 (-2.9A)
 1.47A 4p0wA-4jzxA:
45.6		 4p0wA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.62A 4p0wA-4jzxA:
45.6		 4p0wA-4jzxA:
38.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 11 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.43A 4p0wA-4jzxA:
45.6		 4p0wA-4jzxA:
38.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 6 PHE A 122
ASP A  56
HIS A 347
THR A 113
 None
ZN  A1476 (-2.2A)
ZN  A1476 ( 3.1A)
None
 1.28A 4paeA-2x98A:
undetectable		 4paeA-2x98A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.24A 4q15B-5g0qA:
undetectable		 4q15B-5g0qA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 329
 None
None
IF6  A1476 (-2.9A)
None
None
 1.36A 4q15B-5g0qA:
undetectable		 4q15B-5g0qA:
20.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.63A 4q23A-4jzxA:
44.1		 4q23A-4jzxA:
36.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.37A 4q23A-4jzxA:
44.1		 4q23A-4jzxA:
36.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 9 THR A 128
ALA A 118
ILE A 133
GLY A 131
ASP A  56
 None
None
None
None
ZN  A1476 (-2.2A)
 1.12A 4qvqK-2x98A:
undetectable
4qvqL-2x98A:
undetectable		 4qvqK-2x98A:
23.35
4qvqL-2x98A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 9 THR A 128
ALA A 118
ILE A 133
GLY A 131
ASP A  56
 None
None
None
None
ZN  A1476 (-2.2A)
 1.12A 4qvqY-2x98A:
undetectable
4qvqZ-2x98A:
undetectable		 4qvqY-2x98A:
23.35
4qvqZ-2x98A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 TYR A  79
TYR A 235
GLU A 205
GLN A 256
 None
None
CA  A 476 (-2.4A)
CA  A 476 (-3.2A)
 1.22A 4qztB-3ubrA:
undetectable		 4qztB-3ubrA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3ubr CYTOCHROME C-552
(Shewanella
oneidensis) 		4 / 5 TYR A 235
GLU A 205
LEU A 253
GLN A 256
 None
CA  A 476 (-2.4A)
None
CA  A 476 (-3.2A)
 0.88A 4qztB-3ubrA:
undetectable		 4qztB-3ubrA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2euh NADP DEPENDENT NON
PHOSPHORYLATING
GLYCERALDEHYDE-3-PHO
SPHATE DEHYDROGENASE
(Streptococcus
mutans) 		5 / 12 GLN A 455
ALA A 149
ILE A 150
LEU A 249
GLY A 235
 None
None
NAP  A 476 (-4.5A)
None
None
 1.23A 4r38A-2euhA:
undetectable		 4r38A-2euhA:
15.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.67A 4rxdA-4jzxA:
54.0		 4rxdA-4jzxA:
58.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.45A 4rxdA-4jzxA:
54.0		 4rxdA-4jzxA:
58.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.66A 4rxdB-4jzxA:
54.4		 4rxdB-4jzxA:
58.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.45A 4rxdB-4jzxA:
54.4		 4rxdB-4jzxA:
58.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.66A 4rxdC-4jzxA:
54.4		 4rxdC-4jzxA:
58.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		9 / 10 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.44A 4rxdC-4jzxA:
54.4		 4rxdC-4jzxA:
58.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4uchA-5fjnA:
undetectable
4uchB-5fjnA:
undetectable		 4uchA-5fjnA:
23.40
4uchB-5fjnA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4uchA-5fjnA:
undetectable
4uchB-5fjnA:
undetectable		 4uchA-5fjnA:
23.40
4uchB-5fjnA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4ugzA-5fjnA:
undetectable
4ugzB-5fjnA:
undetectable		 4ugzA-5fjnA:
23.27
4ugzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4uh1A-5fjnA:
undetectable
4uh1B-5fjnA:
undetectable		 4uh1A-5fjnA:
23.27
4uh1B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 4uh1A-5fjnA:
undetectable
4uh1B-5fjnA:
undetectable		 4uh1A-5fjnA:
23.27
4uh1B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 4uh3A-5fjnA:
undetectable
4uh3B-5fjnA:
undetectable		 4uh3A-5fjnA:
23.27
4uh3B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 4uh3A-5fjnA:
undetectable
4uh3B-5fjnA:
undetectable		 4uh3A-5fjnA:
23.27
4uh3B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4uh4A-5fjnA:
undetectable
4uh4B-5fjnA:
undetectable		 4uh4A-5fjnA:
23.27
4uh4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4uh4A-5fjnA:
undetectable
4uh4B-5fjnA:
undetectable		 4uh4A-5fjnA:
23.27
4uh4B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 4uh5A-5fjnA:
undetectable
4uh5B-5fjnA:
undetectable		 4uh5A-5fjnA:
23.66
4uh5B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.30A 4uh6A-5fjnA:
undetectable
4uh6B-5fjnA:
undetectable		 4uh6A-5fjnA:
23.66
4uh6B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4uh6A-5fjnA:
undetectable
4uh6B-5fjnA:
undetectable		 4uh6A-5fjnA:
23.66
4uh6B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 8 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
 0.50A 4umjA-4jzxA:
24.1		 4umjA-4jzxA:
27.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
THR A 208
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
 0.53A 4umjB-4jzxA:
24.2		 4umjB-4jzxA:
27.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
 1.14A 4umjB-4jzxA:
24.2		 4umjB-4jzxA:
27.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4upnA-5fjnA:
undetectable
4upnB-5fjnA:
undetectable		 4upnA-5fjnA:
23.27
4upnB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4upoA-5fjnA:
undetectable
4upoB-5fjnA:
undetectable		 4upoA-5fjnA:
23.27
4upoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 4uppA-5fjnA:
undetectable
4uppB-5fjnA:
undetectable		 4uppA-5fjnA:
23.27
4uppB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4v3uA-5fjnA:
undetectable
4v3uB-5fjnA:
undetectable		 4v3uA-5fjnA:
23.09
4v3uB-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 4v3uC-5fjnA:
undetectable
4v3uD-5fjnA:
undetectable		 4v3uC-5fjnA:
23.09
4v3uD-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4v3uC-5fjnA:
undetectable
4v3uD-5fjnA:
undetectable		 4v3uC-5fjnA:
23.09
4v3uD-5fjnA:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4v3xA-5fjnA:
undetectable
4v3xB-5fjnA:
undetectable		 4v3xA-5fjnA:
23.27
4v3xB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 4v3xA-5fjnA:
undetectable
4v3xB-5fjnA:
undetectable		 4v3xA-5fjnA:
23.27
4v3xB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 4v3yA-5fjnA:
undetectable
4v3yB-5fjnA:
undetectable		 4v3yA-5fjnA:
23.27
4v3yB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 4v3zA-5fjnA:
undetectable
4v3zB-5fjnA:
undetectable		 4v3zA-5fjnA:
23.27
4v3zB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 4v3zA-5fjnA:
undetectable
4v3zB-5fjnA:
undetectable		 4v3zA-5fjnA:
23.27
4v3zB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.24A 4ydqA-5g0qA:
undetectable		 4ydqA-5g0qA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 329
 None
None
IF6  A1476 (-2.9A)
None
None
 1.37A 4ydqA-5g0qA:
undetectable		 4ydqA-5g0qA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3pm9 PUTATIVE
OXIDOREDUCTASE
(Rhodopseudomonas
palustris) 		5 / 11 SER A 156
THR A 157
GLU A  42
THR A 150
GLY A  82
 FAD  A 476 (-2.8A)
FAD  A 476 (-3.2A)
None
FAD  A 476 (-3.1A)
FAD  A 476 (-3.3A)
 1.40A 4zjoD-3pm9A:
6.0		 4zjoD-3pm9A:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.30A 5ad5A-5fjnA:
undetectable
5ad5B-5fjnA:
undetectable		 5ad5A-5fjnA:
23.27
5ad5B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5ad5A-5fjnA:
undetectable
5ad5B-5fjnA:
undetectable		 5ad5A-5fjnA:
23.27
5ad5B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 5ad6A-5fjnA:
undetectable
5ad6B-5fjnA:
undetectable		 5ad6A-5fjnA:
23.27
5ad6B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5ad7A-5fjnA:
undetectable
5ad7B-5fjnA:
undetectable		 5ad7A-5fjnA:
23.27
5ad7B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5ad8A-5fjnA:
undetectable
5ad8B-5fjnA:
undetectable		 5ad8A-5fjnA:
23.27
5ad8B-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.26A 5adbA-5fjnA:
undetectable
5adbB-5fjnA:
undetectable		 5adbA-5fjnA:
23.27
5adbB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 5adcA-5fjnA:
undetectable
5adcB-5fjnA:
undetectable		 5adcA-5fjnA:
23.27
5adcB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.27A 5agkA-5fjnA:
undetectable
5agkB-5fjnA:
undetectable		 5agkA-5fjnA:
23.27
5agkB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.35A 5agmA-5fjnA:
undetectable
5agmB-5fjnA:
undetectable		 5agmA-5fjnA:
23.27
5agmB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 5agnA-5fjnA:
undetectable
5agnB-5fjnA:
undetectable		 5agnA-5fjnA:
23.27
5agnB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 5agnA-5fjnA:
undetectable
5agnB-5fjnA:
undetectable		 5agnA-5fjnA:
23.27
5agnB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.27A 5agpA-5fjnA:
undetectable
5agpB-5fjnA:
undetectable		 5agpA-5fjnA:
23.27
5agpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5agpA-5fjnA:
undetectable
5agpB-5fjnA:
undetectable		 5agpA-5fjnA:
23.27
5agpB-5fjnA:
23.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 12 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.18A 5cg5A-4jzxA:
44.4		 5cg5A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		10 / 12 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.66A 5cg5A-4jzxA:
44.4		 5cg5A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		11 / 12 LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
LYS A 207
THR A 208
TYR A 211
GLN A 247
ASP A 250
LYS A 264
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
None
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.43A 5cg5A-4jzxA:
44.4		 5cg5A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 12 ASP A  98
ARG A 107
GLN A 247
ASP A 250
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 1.12A 5cg6A-4jzxA:
45.2		 5cg6A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 12 PHE A  94
LEU A  95
ARG A 107
THR A 212
LYS A 264
 476  A 402 (-4.3A)
None
476  A 402 (-2.9A)
IPE  A 401 ( 4.6A)
476  A 402 (-2.9A)
 0.96A 5cg6A-4jzxA:
45.2		 5cg6A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		11 / 12 PHE A  94
LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
GLN A 167
LYS A 207
GLN A 247
ASP A 250
LYS A 264
 476  A 402 (-4.3A)
None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.67A 5cg6A-4jzxA:
45.2		 5cg6A-4jzxA:
38.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		11 / 12 PHE A  94
LEU A  95
ASP A  98
ASP A 102
ARG A 107
THR A 163
LYS A 207
THR A 208
GLN A 247
ASP A 250
LYS A 264
 476  A 402 (-4.3A)
None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-4.8A)
476  A 402 (-2.7A)
IPE  A 401 ( 3.4A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
476  A 402 (-2.9A)
 0.40A 5cg6A-4jzxA:
45.2		 5cg6A-4jzxA:
38.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 LEU A  95
ASP A  98
ASP A 102
ARG A 107
LYS A 207
GLN A 247
ASP A 250
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 0.74A 5eroA-4jzxA:
26.9		 5eroA-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 9 ASP A  98
ASP A 102
ARG A 107
LYS A 207
GLN A 247
ASP A 250
ASP A 251
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
None
 0.78A 5eroB-4jzxA:
26.6		 5eroB-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 9 ASP A  98
ASP A 102
LYS A 207
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 1.44A 5eroB-4jzxA:
26.6		 5eroB-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 10 ASP A  98
ASP A  99
ASP A 102
ARG A 107
LYS A 207
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
None
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 0.62A 5eroC-4jzxA:
26.7		 5eroC-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A  98
ASP A 102
LYS A 207
GLN A 247
ASP A 250
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
 1.39A 5eroC-4jzxA:
26.7		 5eroC-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		7 / 10 ASP A  99
ASP A 102
ARG A 107
LYS A 207
GLN A 247
ASP A 250
ASP A 251
 None
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
CA  A 404 (-3.0A)
None
 0.72A 5eroC-4jzxA:
26.7		 5eroC-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A 102
ARG A 107
LYS A 207
ASP A 251
LYS A 264
 CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
None
476  A 402 (-2.9A)
 1.27A 5eroC-4jzxA:
26.7		 5eroC-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 10 ASP A 102
ASP A  99
ARG A 107
ASP A 250
ASP A 251
 CA  A 403 (-2.5A)
None
476  A 402 (-2.9A)
CA  A 404 (-3.0A)
None
 1.48A 5eroC-4jzxA:
26.7		 5eroC-4jzxA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.24A 5f9zA-5g0qA:
undetectable		 5f9zA-5g0qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.28A 5f9zB-5g0qA:
undetectable		 5f9zB-5g0qA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		3 / 3 ARG A 316
VAL A 438
TRP A 439
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 0.98A 5fvoA-5fjnA:
undetectable		 5fvoA-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.37A 5fvpA-5fjnA:
undetectable
5fvpB-5fjnA:
undetectable		 5fvpA-5fjnA:
23.27
5fvpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5fvpA-5fjnA:
undetectable
5fvpB-5fjnA:
undetectable		 5fvpA-5fjnA:
23.27
5fvpB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5fvqA-5fjnA:
undetectable
5fvqB-5fjnA:
undetectable		 5fvqA-5fjnA:
23.27
5fvqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.26A 5fvqA-5fjnA:
undetectable
5fvqB-5fjnA:
undetectable		 5fvqA-5fjnA:
23.27
5fvqB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5fvsA-5fjnA:
undetectable
5fvsB-5fjnA:
undetectable		 5fvsA-5fjnA:
23.27
5fvsB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5fvsA-5fjnA:
undetectable
5fvsB-5fjnA:
undetectable		 5fvsA-5fjnA:
23.27
5fvsB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5fvtA-5fjnA:
undetectable
5fvtB-5fjnA:
undetectable		 5fvtA-5fjnA:
23.27
5fvtB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 5fvtA-5fjnA:
undetectable
5fvtB-5fjnA:
undetectable		 5fvtA-5fjnA:
23.27
5fvtB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 5fvuA-5fjnA:
undetectable
5fvuB-5fjnA:
undetectable		 5fvuA-5fjnA:
23.66
5fvuB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 5fvuA-5fjnA:
undetectable
5fvuB-5fjnA:
undetectable		 5fvuA-5fjnA:
23.66
5fvuB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 5fvvA-5fjnA:
undetectable
5fvvB-5fjnA:
undetectable		 5fvvA-5fjnA:
23.66
5fvvB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 5fvvA-5fjnA:
undetectable
5fvvB-5fjnA:
undetectable		 5fvvA-5fjnA:
23.66
5fvvB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.28A 5fvxA-5fjnA:
undetectable
5fvxB-5fjnA:
undetectable		 5fvxA-5fjnA:
23.66
5fvxB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.29A 5g0nA-5fjnA:
undetectable
5g0nB-5fjnA:
undetectable		 5g0nA-5fjnA:
23.27
5g0nB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 5g0nA-5fjnA:
undetectable
5g0nB-5fjnA:
undetectable		 5g0nA-5fjnA:
23.27
5g0nB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 5g0oA-5fjnA:
undetectable
5g0oB-5fjnA:
undetectable		 5g0oA-5fjnA:
23.27
5g0oB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 5g0pA-5fjnA:
undetectable
5g0pB-5fjnA:
undetectable		 5g0pA-5fjnA:
23.54
5g0pB-5fjnA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		3 / 3 TRP A 260
GLU A 236
ASP A 255
 None
None
MG  A 476 (-2.8A)
 0.50A 5gqbA-3nxlA:
5.1		 5gqbA-3nxlA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 10 THR A 128
ALA A 118
ALA A 132
GLY A 131
ASP A  56
 None
None
None
None
ZN  A1476 (-2.2A)
 1.14A 5lf3H-2x98A:
undetectable
5lf3I-2x98A:
undetectable		 5lf3H-2x98A:
19.03
5lf3I-2x98A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 GLY A 345
HIS A 347
VAL A 303
ILE A  51
ALA A  52
 None
ZN  A1476 ( 3.1A)
None
None
None
 1.09A 5n0sA-2x98A:
2.4		 5n0sA-2x98A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 GLY A 345
HIS A 347
VAL A 303
ILE A  51
ALA A  52
 None
ZN  A1476 ( 3.1A)
None
None
None
 1.09A 5n0wB-2x98A:
3.2		 5n0wB-2x98A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 12 GLY A 345
HIS A 347
VAL A 303
ILE A  51
ALA A  52
 None
ZN  A1476 ( 3.1A)
None
None
None
 1.09A 5n0xA-2x98A:
3.1		 5n0xA-2x98A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 7 ASP A  56
GLY A 301
ASP A 346
HIS A 308
ASP A 304
 ZN  A1476 (-2.2A)
MG  A1477 ( 4.5A)
ZN  A1476 (-2.3A)
ZN  A1475 ( 3.2A)
ZN  A1475 ( 2.0A)
 1.45A 5nnwD-2x98A:
undetectable		 5nnwD-2x98A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		5 / 7 ASP A  56
GLY A 301
ASP A 346
HIS A 308
ASP A 304
 ZN  A1476 (-2.2A)
MG  A1477 ( 4.5A)
ZN  A1476 (-2.3A)
ZN  A1475 ( 3.2A)
ZN  A1475 ( 2.0A)
 1.49A 5no9D-2x98A:
undetectable		 5no9D-2x98A:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1htq GLUTAMINE SYNTHETASE
(Mycobacterium
tuberculosis) 		5 / 12 LEU A 322
GLY A 265
GLU A 131
GLY A 267
ARG A 359
 None
CIT  A7476 (-3.2A)
CIT  A7476 (-2.7A)
CIT  A7476 (-3.8A)
MN  A 470 (-3.4A)
 1.20A 5o4yD-1htqA:
undetectable
5o4yE-1htqA:
0.0		 5o4yD-1htqA:
20.00
5o4yE-1htqA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 11 LEU A 326
GLY A 329
LEU A 318
ARG A 312
ALA A 315
 None
CAP  A 476 ( 4.3A)
None
None
None
 1.13A 5o96A-1rblA:
undetectable
5o96B-1rblA:
3.5		 5o96A-1rblA:
20.44
5o96B-1rblA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		4 / 8 GLU A 287
GLU A 173
GLY A  78
THR A  81
 IF6  A1476 (-1.9A)
IF6  A1476 (-3.1A)
None
None
 1.05A 5sxqB-5g0qA:
undetectable		 5sxqB-5g0qA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		4 / 8 GLU A 287
GLU A 173
GLY A  78
THR A  81
 IF6  A1476 (-1.9A)
IF6  A1476 (-3.1A)
None
None
 1.04A 5syjA-5g0qA:
undetectable		 5syjA-5g0qA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5unsA-5fjnA:
undetectable
5unsB-5fjnA:
undetectable		 5unsA-5fjnA:
23.27
5unsB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 5unsA-5fjnA:
undetectable
5unsB-5fjnA:
undetectable		 5unsA-5fjnA:
23.27
5unsB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5untA-5fjnA:
undetectable
5untB-5fjnA:
undetectable		 5untA-5fjnA:
23.27
5untB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 5untA-5fjnA:
undetectable
5untB-5fjnA:
undetectable		 5untA-5fjnA:
23.27
5untB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 5unzA-5fjnA:
undetectable
5unzB-5fjnA:
undetectable		 5unzA-5fjnA:
23.27
5unzB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 5uo2A-5fjnA:
undetectable
5uo2B-5fjnA:
undetectable		 5uo2A-5fjnA:
23.66
5uo2B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 5uo2A-5fjnA:
undetectable
5uo2B-5fjnA:
undetectable		 5uo2A-5fjnA:
23.66
5uo2B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 5uo3A-5fjnA:
undetectable
5uo3B-5fjnA:
undetectable		 5uo3A-5fjnA:
23.66
5uo3B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 5uo4A-5fjnA:
undetectable
5uo4B-5fjnA:
undetectable		 5uo4A-5fjnA:
23.66
5uo4B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 8 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.30A 5uo7A-5fjnA:
undetectable
5uo7B-5fjnA:
undetectable		 5uo7A-5fjnA:
23.66
5uo7B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 5vunA-5fjnA:
undetectable
5vunB-5fjnA:
undetectable		 5vunA-5fjnA:
23.27
5vunB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 5vunA-5fjnA:
undetectable
5vunB-5fjnA:
undetectable		 5vunA-5fjnA:
23.27
5vunB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.35A 5vuoA-5fjnA:
undetectable
5vuoB-5fjnA:
undetectable		 5vuoA-5fjnA:
23.27
5vuoB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 5vupA-5fjnA:
undetectable
5vupB-5fjnA:
undetectable		 5vupA-5fjnA:
23.27
5vupB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 5vutA-5fjnA:
undetectable
5vutB-5fjnA:
undetectable		 5vutA-5fjnA:
23.27
5vutB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.32A 5vutA-5fjnA:
undetectable
5vutB-5fjnA:
undetectable		 5vutA-5fjnA:
23.27
5vutB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 5vuuA-5fjnA:
undetectable
5vuuB-5fjnA:
undetectable		 5vuuA-5fjnA:
23.27
5vuuB-5fjnA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 5vuwA-5fjnA:
undetectable
5vuwB-5fjnA:
undetectable		 5vuwA-5fjnA:
23.66
5vuwB-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 6 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.36A 5vv1A-5fjnA:
undetectable
5vv1B-5fjnA:
undetectable		 5vv1A-5fjnA:
23.66
5vv1B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.34A 5vv2A-5fjnA:
undetectable
5vv2B-5fjnA:
undetectable		 5vv2A-5fjnA:
23.66
5vv2B-5fjnA:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		4 / 7 ASN A 309
ASP A 281
GLY A 228
ASN A 257
 MG  A 476 (-2.4A)
None
None
MG  A 476 ( 4.3A)
 1.13A 5x7pA-3nxlA:
undetectable		 5x7pA-3nxlA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		4 / 7 HIS A  36
ASP A 255
GLY A 228
ASN A  31
 CO3  A 477 (-4.0A)
MG  A 476 (-2.8A)
None
CO3  A 477 ( 3.8A)
 1.12A 5x7pA-3nxlA:
undetectable		 5x7pA-3nxlA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3nxl GLUCARATE
DEHYDRATASE
(Burkholderia
lata) 		4 / 5 HIS A  36
ASP A 255
GLY A 228
ASN A  31
 CO3  A 477 (-4.0A)
MG  A 476 (-2.8A)
None
CO3  A 477 ( 3.8A)
 1.12A 5x7pB-3nxlA:
undetectable		 5x7pB-3nxlA:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		5 / 12 LEU A 176
GLU A 245
GLU A  45
SER A  43
GLY A 328
 None
None
IF6  A1476 (-2.9A)
None
None
 1.26A 5xiqA-5g0qA:
undetectable		 5xiqA-5g0qA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 6auqA-5fjnA:
undetectable
6auqB-5fjnA:
undetectable		 6auqA-5fjnA:
10.96
6auqB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 6aurA-5fjnA:
undetectable
6aurB-5fjnA:
undetectable		 6aurA-5fjnA:
10.96
6aurB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.33A 6aurA-5fjnA:
undetectable
6aurB-5fjnA:
undetectable		 6aurA-5fjnA:
10.96
6aurB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.30A 6ausA-5fjnA:
undetectable
6ausB-5fjnA:
undetectable		 6ausA-5fjnA:
10.96
6ausB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 6ausA-5fjnA:
undetectable
6ausB-5fjnA:
undetectable		 6ausA-5fjnA:
10.96
6ausB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.27A 6autA-5fjnA:
undetectable
6autB-5fjnA:
undetectable		 6autA-5fjnA:
10.96
6autB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.26A 6auuA-5fjnA:
undetectable
6auuB-5fjnA:
undetectable		 6auuA-5fjnA:
10.96
6auuB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 6auvA-5fjnA:
undetectable
6auvB-5fjnA:
undetectable		 6auvA-5fjnA:
10.96
6auvB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 6auvA-5fjnA:
undetectable
6auvB-5fjnA:
undetectable		 6auvA-5fjnA:
10.96
6auvB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.34A 6auwA-5fjnA:
undetectable
6auwB-5fjnA:
undetectable		 6auwA-5fjnA:
10.96
6auwB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.28A 6auxA-5fjnA:
undetectable
6auxB-5fjnA:
undetectable		 6auxA-5fjnA:
10.96
6auxB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.28A 6auxA-5fjnA:
undetectable
6auxB-5fjnA:
undetectable		 6auxA-5fjnA:
10.96
6auxB-5fjnA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 6auyA-5fjnA:
undetectable
6auyB-5fjnA:
undetectable		 6auyA-5fjnA:
9.61
6auyB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.30A 6auyA-5fjnA:
undetectable
6auyB-5fjnA:
undetectable		 6auyA-5fjnA:
9.61
6auyB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.28A 6auzA-5fjnA:
undetectable
6auzB-5fjnA:
undetectable		 6auzA-5fjnA:
9.61
6auzB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 6auzA-5fjnA:
undetectable
6auzB-5fjnA:
undetectable		 6auzA-5fjnA:
9.61
6auzB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 6av0A-5fjnA:
undetectable
6av0B-5fjnA:
undetectable		 6av0A-5fjnA:
9.61
6av0B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.26A 6av0A-5fjnA:
undetectable
6av0B-5fjnA:
undetectable		 6av0A-5fjnA:
9.61
6av0B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 6av2A-5fjnA:
undetectable
6av2B-5fjnA:
undetectable		 6av2A-5fjnA:
9.61
6av2B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.27A 6av2A-5fjnA:
undetectable
6av2B-5fjnA:
undetectable		 6av2A-5fjnA:
9.61
6av2B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 6av3A-5fjnA:
undetectable
6av3B-5fjnA:
undetectable		 6av3A-5fjnA:
9.61
6av3B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.32A 6av4A-5fjnA:
undetectable
6av4B-5fjnA:
undetectable		 6av4A-5fjnA:
9.61
6av4B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.27A 6av4A-5fjnA:
undetectable
6av4B-5fjnA:
undetectable		 6av4A-5fjnA:
9.61
6av4B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.31A 6av5A-5fjnA:
undetectable
6av5B-5fjnA:
undetectable		 6av5A-5fjnA:
9.61
6av5B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.29A 6av5A-5fjnA:
undetectable
6av5B-5fjnA:
undetectable		 6av5A-5fjnA:
9.61
6av5B-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 6cicA-5fjnA:
undetectable
6cicB-5fjnA:
undetectable		 6cicA-5fjnA:
9.61
6cicB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 6cicA-5fjnA:
undetectable
6cicB-5fjnA:
undetectable		 6cicA-5fjnA:
9.61
6cicB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 ARG A 316
VAL A 438
TRP A 439
GLU A 418
 BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
None
 1.33A 6cidA-5fjnA:
undetectable
6cidB-5fjnA:
undetectable		 6cidA-5fjnA:
9.61
6cidB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5fjn L-AMINO ACID
DEAMINASE
(Cosenzaea
myxofaciens) 		4 / 7 GLU A 418
ARG A 316
VAL A 438
TRP A 439
 None
BE2  A1476 (-4.0A)
BE2  A1476 ( 4.3A)
BE2  A1476 ( 3.7A)
 1.31A 6cidA-5fjnA:
undetectable
6cidB-5fjnA:
undetectable		 6cidA-5fjnA:
9.61
6cidB-5fjnA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 4 MET A  58
GLY A  57
HIS A 347
GLY A  59
 None
None
ZN  A1476 ( 3.1A)
None
 1.36A 6fgdA-2x98A:
undetectable		 6fgdA-2x98A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 2x98 ALKALINE PHOSPHATASE
(Halobacterium
salinarum) 		4 / 4 MET A  58
GLY A  57
HIS A 347
GLY A 345
 None
None
ZN  A1476 ( 3.1A)
None
 0.99A 6fgdA-2x98A:
undetectable		 6fgdA-2x98A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 7 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
 1.04A 6g31A-4jzxA:
25.3		 6g31A-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 6 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.83A 6g31B-4jzxA:
25.2		 6g31B-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 5 ASP A  98
ASP A 102
ARG A 107
LYS A 207
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-2.7A)
 1.12A 6g31C-4jzxA:
25.6		 6g31C-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 5 ASP A  98
ASP A 102
GLN A 167
LYS A 207
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
 1.11A 6g31C-4jzxA:
25.6		 6g31C-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 7 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.67A 6g31D-4jzxA:
24.9		 6g31D-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_E_ZOLE401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 4 LEU A  95
ASP A  98
ASP A 102
ARG A 107
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
 0.45A 6g31E-4jzxA:
19.3		 6g31E-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 5 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.89A 6g31F-4jzxA:
25.4		 6g31F-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 7 ASP A  98
ASP A 102
ARG A 107
GLN A 167
LYS A 207
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
 0.82A 6g31G-4jzxA:
24.3		 6g31G-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 5 ASP A  98
ASP A 102
GLN A 167
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 0.59A 6g31H-4jzxA:
24.3		 6g31H-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_I_ZOLI401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 4 ASP A  98
ASP A 102
LYS A 207
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.7A)
IPE  A 401 (-3.7A)
 0.96A 6g31I-4jzxA:
24.2		 6g31I-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		6 / 6 LEU A  95
ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 None
CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 1.01A 6g31J-4jzxA:
25.7		 6g31J-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 4 ASP A  98
ASP A 102
ARG A 107
GLN A 167
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
 0.63A 6g31K-4jzxA:
23.3		 6g31K-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		5 / 6 ASP A  98
ASP A 102
ARG A 107
GLN A 167
GLN A 247
 CA  A 403 (-2.5A)
CA  A 403 (-2.5A)
476  A 402 (-2.9A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
 1.07A 6g31L-4jzxA:
25.2		 6g31L-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 4jzx FARNESYL
PYROPHOSPHATE
SYNTHASE
(Leishmania
major) 		4 / 6 ASP A  98
GLN A 167
GLN A 247
LYS A 273
 CA  A 403 (-2.5A)
476  A 402 (-3.5A)
IPE  A 401 (-3.7A)
CA  A 403 ( 4.9A)
 1.34A 6g31L-4jzxA:
25.2		 6g31L-4jzxA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_2
(-)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		4 / 6 TYR A 334
HIS A 241
TYR A 292
GLU A 268
 IF6  A1476 (-4.4A)
None
IF6  A1476 (-4.0A)
None
 1.27A 6gneA-5g0qA:
undetectable		 6gneA-5g0qA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_2
(-)		 5g0q BETA-GLUCURONIDASE
(Acidobacterium
capsulatum) 		4 / 8 TYR A 334
HIS A 241
TYR A 292
GLU A 268
 IF6  A1476 (-4.4A)
None
IF6  A1476 (-4.0A)
None
 1.27A 6gneB-5g0qA:
undetectable		 6gneB-5g0qA:
21.83