SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3VK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6F_C_010C6_0
(INFECTIOUS
BRONCHITIS VIRUS
(IBV) MAIN PROTEASE
N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 ASN A  44
LEU A  56
HIS A  54
 3VK  A 301 (-3.5A)
None
3VK  A 301 (-4.2A)
 0.80A 2q6fB-4wx6A:
undetectable		 2q6fB-4wx6A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 0.93A 3aicA-4wx6A:
undetectable		 3aicA-4wx6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 0.91A 3aicB-4wx6A:
undetectable		 3aicB-4wx6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 0.94A 3aicE-4wx6A:
undetectable		 3aicE-4wx6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 1.00A 3aicF-4wx6A:
undetectable		 3aicF-4wx6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 0.95A 3aicG-4wx6A:
undetectable		 3aicG-4wx6A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 4wx6 PROTEASE
(Human
mastadenovirus
D) 		3 / 3 LEU A 178
TRP A  55
TYR A 184
 None
3VK  A 301 (-3.7A)
None
 0.94A 3aicH-4wx6A:
undetectable		 3aicH-4wx6A:
13.41