SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3VB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOF_C_FRDC305_1 (POL POLYPROTEIN PEPTIDE INHIBITOR)	4rsm	PERIPLASMIC BINDING PROTEIN/LACI TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	4 / 5	ASP A 249 GLY A 163 ALA A 140 ILE A 248	3VB A 401 (-2.7A) None None None	0.86A	2aofA-4rsmA: undetectable	2aofA-4rsmA: 15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PMZ_E_TUBE220_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4rsm	PERIPLASMIC BINDING PROTEIN/LACI TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	4 / 6	GLN A 269 MET A 299 SER A 45 SER A 46	3VB A 401 (-3.1A) None 3VB A 401 ( 4.7A) None	1.04A	3pmzD-4rsmA: undetectable	3pmzD-4rsmA: 18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4HXY_B_ACAB502_1 (PLM1)	4rsm	PERIPLASMIC BINDING PROTEIN/LACI TRANSCRIPTIONAL REGULATOR (Mycolicibacteriu m smegmatis)	4 / 7	VAL A 96 SER A 45 TYR A 42 LEU A 275	None 3VB A 401 ( 4.7A) 3VB A 401 (-4.5A) None	1.21A	4hxyB-4rsmA: undetectable	4hxyB-4rsmA: 23.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2AOF_C_FRDC305_1","POL POLYPROTEIN;PEPTIDE INHIBITOR","4rsm","PERIPLASMIC BINDING PROTEIN\/LACI TRANSCRIPTIONAL REGULATOR","Mycolicibacterium smegmatis",4,"ASP A 249;GLY A 163;ALA A 140;ILE A 248","3VB A 401 (-2.7A);None;None;None","0.86A","2aofA-4rsmA:undetectable",null],["3PMZ_E_TUBE220_1","SOLUBLE ACETYLCHOLINE RECEPTOR;SOLUBLE ACETYLCHOLINE RECEPTOR","4rsm","PERIPLASMIC BINDING PROTEIN\/LACI TRANSCRIPTIONAL REGULATOR","Mycolicibacterium smegmatis",4,"GLN A 269;MET A 299;SER A  45;SER A  46","3VB A 401 (-3.1A);None;3VB A 401 ( 4.7A);None","1.04A","3pmzD-4rsmA:undetectable","2aofA-4rsmA:15.58"],["4HXY_B_ACAB502_1","PLM1","4rsm","PERIPLASMIC BINDING PROTEIN\/LACI TRANSCRIPTIONAL REGULATOR","Mycolicibacterium smegmatis",4,"VAL A  96;SER A  45;TYR A  42;LEU A 275","None;3VB A 401 ( 4.7A);3VB A 401 (-4.5A);None","1.21A","4hxyB-4rsmA:undetectable","3pmzD-4rsmA:18.02"]]