SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3V9'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		3 / 3 GLY A  51
GLU A  70
ASN A  53
 None
3V9  A 303 (-3.2A)
None
 0.49A 1zq9A-5elzA:
undetectable		 1zq9A-5elzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A  95
ILE A 117
GLY A 116
GLY A 115
VAL A 114
 None
None
3V9  A 303 (-3.2A)
None
None
 0.88A 2avsA-5elzA:
undetectable		 2avsA-5elzA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.50A 5e26A-5elzA:
29.5
5e26B-5elzA:
29.6		 5e26A-5elzA:
26.26
5e26B-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.44A 5e26A-5elzA:
29.5
5e26B-5elzA:
29.6		 5e26A-5elzA:
26.26
5e26B-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.44A 5e26C-5elzA:
29.8
5e26D-5elzA:
29.8		 5e26C-5elzA:
26.26
5e26D-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 8 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.46A 5e26C-5elzA:
29.8
5e26D-5elzA:
29.9		 5e26C-5elzA:
26.26
5e26D-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 5 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.54A 5kprA-5elzA:
29.8		 5kprA-5elzA:
24.48