SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3TL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.70A 1c6yA-3slzA:
11.8		 1c6yA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_1
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.63A 1c6yA-6fivA:
15.7		 1c6yA-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.55A 1c6yB-3slzA:
11.9		 1c6yB-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Y_B_MK1B524_2
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.30A 1c6yB-6fivA:
15.8		 1c6yB-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.72A 1c6zA-3slzA:
11.8		 1c6zA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.31A 1c6zA-6fivA:
15.3		 1c6zA-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.74A 1c6zB-3slzA:
11.9		 1c6zB-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.53A 1c6zB-6fivA:
15.6		 1c6zB-6fivA:
26.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.65A 1d4sA-3slzA:
10.9		 1d4sA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.81A 1d4sA-3slzA:
10.9		 1d4sA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_1
(PROTEIN (HIV-1
PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 1d4sA-6fivA:
15.2		 1d4sA-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 1d4yA-6fivA:
15.4		 1d4yA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.66A 1fb7A-3slzA:
11.3		 1fb7A-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 1fb7A-6fivA:
15.7		 1fb7A-6fivA:
30.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-3.4A)
 0.62A 1hpvA-3slzA:
11.4		 1hpvA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-4.0A)
 0.71A 1hpvA-3slzA:
11.4		 1hpvA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.59A 1hsgA-3slzA:
11.3		 1hsgA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.60A 1hsgA-3slzA:
11.3		 1hsgA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.57A 1hsgA-6fivA:
15.4		 1hsgA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.60A 1hsgA-6fivA:
15.4		 1hsgA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 1hsgB-3slzA:
11.4		 1hsgB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.64A 1hsgB-3slzA:
11.4		 1hsgB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 1hsgB-6fivA:
15.6		 1hsgB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.34A 1hshA-3slzA:
12.3		 1hshA-3slzA:
25.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HSH_C_MK1C402_1
(HIV-II PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.26A 1hshC-6fivA:
16.3		 1hshC-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 1hxbA-3slzA:
11.3		 1hxbA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 1hxbA-6fivA:
15.5		 1hxbA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 1hxbB-3slzA:
11.2		 1hxbB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.47A 1hxbB-6fivA:
15.5		 1hxbB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.59A 1hxbB-6fivA:
15.5		 1hxbB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
GLY A  32
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.62A 1hxwA-6fivA:
15.5		 1hxwA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		7 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.77A 1hxwB-3slzA:
11.3		 1hxwB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.52A 1hxwB-6fivA:
15.4		 1hxwB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 1k6cA-3slzA:
11.4		 1k6cA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.69A 1k6cA-3slzA:
11.4		 1k6cA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 1k6cB-3slzA:
11.2		 1k6cB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.71A 1k6cB-3slzA:
11.2		 1k6cB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.60A 1k6cB-6fivA:
15.4		 1k6cB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.56A 1muiA-3slzA:
11.2		 1muiA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.67A 1muiA-3slzA:
11.2		 1muiA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.30A 1muiA-6fivA:
15.7		 1muiA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.87A 1ohrA-3slzA:
11.2		 1ohrA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 1ohrA-6fivA:
15.5		 1ohrA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_2
(ASPARTYLPROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.71A 1ohrB-3slzA:
11.2		 1ohrB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.56A 1rl8A-3slzA:
11.1		 1rl8A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.72A 1rl8A-3slzA:
11.1		 1rl8A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RL8_A_RITA9001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.48A 1rl8B-3slzA:
11.1		 1rl8B-3slzA:
27.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 1sdtB-6fivA:
15.5		 1sdtB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 1sduA-6fivA:
15.3		 1sduA-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.32A 1sduB-6fivA:
15.5		 1sduB-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 1sduB-6fivA:
15.5		 1sduB-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.58A 1sdvA-6fivA:
15.6		 1sdvA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 1sdvB-3slzA:
11.0		 1sdvB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.81A 1sdvB-3slzA:
11.0		 1sdvB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 1sdvB-6fivA:
15.5		 1sdvB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.46A 1sguB-6fivA:
15.7		 1sguB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.48A 1sguB-6fivA:
15.7		 1sguB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.27A 1t3rA-3slzA:
11.1		 1t3rA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 1t3rA-6fivA:
15.3		 1t3rA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.83A 1t3rB-3slzA:
11.3		 1t3rB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.54A 1t3rB-3slzA:
11.3		 1t3rB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.27A 1t7iA-3slzA:
11.2		 1t7iA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 1t7iA-6fivA:
15.2		 1t7iA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7I_A_017A200_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 7 ASP A  32
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.48A 1t7iB-3slzA:
11.1		 1t7iB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 1t7jA-3slzA:
11.3		 1t7jA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T7J_A_478A200_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 7 ASP A  32
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.54A 1t7jB-3slzA:
11.2		 1t7jB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2aquA-6fivA:
15.5		 2aquA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2aquB-6fivA:
15.4		 2aquB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.57A 2avoB-3slzA:
11.1		 2avoB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.69A 2avoB-3slzA:
11.1		 2avoB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.62A 2avsA-3slzA:
11.1		 2avsA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.55A 2avsA-6fivA:
15.2		 2avsA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.47A 2avsA-6fivA:
15.2		 2avsA-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.58A 2avsB-3slzA:
11.0		 2avsB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.74A 2avsB-3slzA:
11.0		 2avsB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.41A 2avsB-6fivA:
15.3		 2avsB-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.35A 2avvA-3slzA:
11.2		 2avvA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
None
 0.61A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.44A 2avvA-6fivA:
15.3		 2avvA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 2avvB-3slzA:
11.3		 2avvB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.51A 2avvB-3slzA:
11.3		 2avvB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 2avvD-3slzA:
11.4		 2avvD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.51A 2avvD-3slzA:
11.4		 2avvD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
 0.48A 2avvD-6fivA:
15.3		 2avvD-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2avvD-6fivA:
15.3		 2avvD-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 2avvE-3slzA:
11.2		 2avvE-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.33A 2avvE-6fivA:
15.5		 2avvE-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_3
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.48A 2avvE-6fivA:
15.5		 2avvE-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 2b60A-6fivA:
15.8		 2b60A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.47A 2b60A-6fivA:
15.8		 2b60A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_2
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 2b60B-6fivA:
15.8		 2b60B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 2b7zA-6fivA:
15.8		 2b7zA-6fivA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 2b7zB-6fivA:
15.8		 2b7zB-6fivA:
27.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.56A 2bpxB-3slzA:
11.4		 2bpxB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.53A 2f80A-3slzA:
11.2		 2f80A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 2f80A-3slzA:
11.2		 2f80A-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 2f80A-6fivA:
15.5		 2f80A-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.57A 2f80B-3slzA:
11.4		 2f80B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 2f80B-3slzA:
11.4		 2f80B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2f80B-6fivA:
15.6		 2f80B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F80_B_017B301_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.41A 2f80B-6fivA:
15.6		 2f80B-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.53A 2f81A-3slzA:
11.2		 2f81A-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 2f81A-3slzA:
11.2		 2f81A-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2f81A-6fivA:
15.5		 2f81A-6fivA:
31.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.50A 2f81A-6fivA:
15.5		 2f81A-6fivA:
31.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.58A 2f81B-3slzA:
11.3		 2f81B-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.41A 2f81B-3slzA:
11.3		 2f81B-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F81_A_017A302_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.38A 2f81B-6fivA:
15.6		 2f81B-6fivA:
31.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.46A 2f8gA-3slzA:
11.2		 2f8gA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8G_B_017B401_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.22A 2f8gA-6fivA:
15.6		 2f8gA-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.60A 2f8gB-3slzA:
11.2		 2f8gB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.45A 2f8gB-3slzA:
11.2		 2f8gB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.33A 2fxdA-3slzA:
11.7		 2fxdA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_1
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 2fxdA-6fivA:
15.3		 2fxdA-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXD_A_DR7A102_2
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 7 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.33A 2fxdB-6fivA:
15.5		 2fxdB-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_1
(POL PROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 2fxeA-3slzA:
11.1		 2fxeA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2fxeB-6fivA:
15.5		 2fxeB-6fivA:
27.83
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.35A 2hs1A-6fivA:
15.1		 2hs1A-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.52A 2hs1B-3slzA:
11.2		 2hs1B-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 2hs1B-6fivA:
15.6		 2hs1B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.61A 2hs1B-6fivA:
15.6		 2hs1B-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.24A 2hs2A-3slzA:
11.0		 2hs2A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 2hs2A-6fivA:
15.0		 2hs2A-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.32A 2hs2B-3slzA:
11.1		 2hs2B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.52A 2hs2B-3slzA:
11.1		 2hs2B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.48A 2hs2B-6fivA:
15.6		 2hs2B-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.62A 2idwA-3slzA:
11.0		 2idwA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 2idwB-3slzA:
11.0		 2idwB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IDW_B_017B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2idwB-6fivA:
15.3		 2idwB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.57A 2ienA-3slzA:
11.1		 2ienA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 2ienA-3slzA:
11.1		 2ienA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.45A 2ienB-3slzA:
11.3		 2ienB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.68A 2ienB-3slzA:
11.3		 2ienB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEN_B_017B402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.34A 2ienB-6fivA:
15.6		 2ienB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.57A 2ieoA-3slzA:
11.2		 2ieoA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 2ieoA-3slzA:
11.2		 2ieoA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.55A 2ieoB-3slzA:
11.4		 2ieoB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.46A 2ieoB-3slzA:
11.4		 2ieoB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEO_A_017A402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2ieoB-6fivA:
15.6		 2ieoB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2IEO_A_017A402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.44A 2ieoB-6fivA:
15.6		 2ieoB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NMY_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 2nmyA-6fivA:
15.1		 2nmyA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.36A 2nmyB-3slzA:
11.1		 2nmyB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NMY_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.22A 2nmyB-6fivA:
15.2		 2nmyB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.33A 2nmzB-3slzA:
11.0		 2nmzB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.53A 2nnkA-3slzA:
11.1		 2nnkA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.27A 2nnkA-3slzA:
11.1		 2nnkA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNK_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.41A 2nnkA-6fivA:
15.2		 2nnkA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 2nnkB-3slzA:
11.3		 2nnkB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNP_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.49A 2nnpA-3slzA:
11.1		 2nnpA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.55A 2nnpA-6fivA:
15.1		 2nnpA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.31A 2nnpB-6fivA:
15.3		 2nnpB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNP_A_ROCA401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.33A 2nnpB-6fivA:
15.3		 2nnpB-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4K_A_DR7A301_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.29A 2o4kA-6fivA:
15.6		 2o4kA-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.53A 2o4kB-3slzA:
11.2		 2o4kB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.66A 2o4kB-3slzA:
11.2		 2o4kB-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4L_A_TPVA403_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.52A 2o4lA-6fivA:
15.5		 2o4lA-6fivA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4L_A_TPVA403_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 2o4lA-6fivA:
15.5		 2o4lA-6fivA:
31.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4P_A_TPVA300_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.56A 2o4pA-6fivA:
15.4		 2o4pA-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.56A 2o4pB-3slzA:
11.2		 2o4pB-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4P_A_TPVA300_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.42A 2o4pB-6fivA:
15.5		 2o4pB-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.85A 2o4sA-3slzA:
11.3		 2o4sA-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 2o4sA-6fivA:
15.6		 2o4sA-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.23A 2o4sB-6fivA:
15.5		 2o4sB-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2O4S_A_AB1A400_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.58A 2o4sB-6fivA:
15.5		 2o4sB-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.50A 2pymA-3slzA:
11.3		 2pymA-3slzA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 2pymA-3slzA:
11.3		 2pymA-3slzA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.38A 2pymA-6fivA:
15.5		 2pymA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.50A 2pymB-3slzA:
11.3		 2pymB-3slzA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 2pymB-3slzA:
11.3		 2pymB-3slzA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 2pymB-6fivA:
15.5		 2pymB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.52A 2pynA-3slzA:
11.6		 2pynA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.53A 2pynA-3slzA:
11.6		 2pynA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 2pynA-6fivA:
15.8		 2pynA-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 2pynB-3slzA:
11.6		 2pynB-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.42A 2pynB-6fivA:
15.8		 2pynB-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.96A 2q5kA-3slzA:
11.1		 2q5kA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 2q5kA-6fivA:
15.0		 2q5kA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 2q5kB-3slzA:
11.3		 2q5kB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.75A 2q5kB-3slzA:
11.3		 2q5kB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.64A 2q5kB-6fivA:
15.4		 2q5kB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 2q5kB-6fivA:
15.4		 2q5kB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.53A 2q63B-3slzA:
11.3		 2q63B-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 2q63B-3slzA:
11.3		 2q63B-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 2q63B-6fivA:
15.6		 2q63B-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.52A 2q64A-3slzA:
11.2		 2q64A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 2q64A-3slzA:
11.2		 2q64A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 2q64A-6fivA:
15.5		 2q64A-6fivA:
27.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 2q64B-3slzA:
11.2		 2q64B-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		7 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.69A 2qakA-3slzA:
11.2		 2qakA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 2qakB-3slzA:
11.3		 2qakB-3slzA:
26.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.18A 2qakB-6fivA:
15.6		 2qakB-6fivA:
30.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.39A 2qakB-6fivA:
15.6		 2qakB-6fivA:
30.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.72A 2qhcA-6fivA:
15.3		 2qhcA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.70A 2qhcB-3slzA:
11.0		 2qhcB-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.58A 2qhcB-3slzA:
11.0		 2qhcB-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2qhcB-6fivA:
15.4		 2qhcB-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.43A 2qhcB-6fivA:
15.4		 2qhcB-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 2r5pB-3slzA:
11.3		 2r5pB-3slzA:
24.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.74A 2r5pB-3slzA:
11.3		 2r5pB-3slzA:
24.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2R5Q_B_1UNB900_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 2r5qB-6fivA:
15.7		 2r5qB-6fivA:
31.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2R5Q_D_1UND900_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 2r5qD-6fivA:
15.7		 2r5qD-6fivA:
31.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.34A 2rkfA-3slzA:
11.3		 2rkfA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 2rkfA-6fivA:
15.6		 2rkfA-6fivA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_1
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.47A 2rkgA-3slzA:
11.6		 2rkgA-3slzA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.48A 2rkgB-3slzA:
11.6		 2rkgB-3slzA:
26.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKG_B_AB1B501_2
(PROTEASE RETROPEPSIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 2rkgB-6fivA:
15.9		 2rkgB-6fivA:
28.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WM3_A_NFLA1301_1
(NMRA-LIKE FAMILY
DOMAIN CONTAINING
PROTEIN 1)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 6 LEU A  40
THR A  41
PHE A  29
LEU A  92
 None
None
None
3TL  A 126 (-4.6A)
 0.91A 2wm3A-3slzA:
undetectable		 2wm3A-3slzA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.58A 2z54A-3slzA:
11.1		 2z54A-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.58A 2z54A-3slzA:
11.1		 2z54A-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 2z54A-6fivA:
15.4		 2z54A-6fivA:
27.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.61A 2z54B-3slzA:
11.1		 2z54B-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.54A 2z54B-3slzA:
11.1		 2z54B-3slzA:
28.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 3bvbA-3slzA:
11.1		 3bvbA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.48A 3bvbB-3slzA:
11.4		 3bvbB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.53A 3cywA-3slzA:
11.1		 3cywA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 3cywA-3slzA:
11.1		 3cywA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.37A 3cywA-6fivA:
15.4		 3cywA-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.53A 3cywA-6fivA:
15.4		 3cywA-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.60A 3cywB-3slzA:
11.3		 3cywB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3cywB-3slzA:
11.3		 3cywB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 3cywB-6fivA:
15.6		 3cywB-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.51A 3cywB-6fivA:
15.6		 3cywB-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.32A 3cyxA-3slzA:
11.1		 3cyxA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.36A 3cyxA-6fivA:
15.4		 3cyxA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 3cyxA-6fivA:
15.4		 3cyxA-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.32A 3cyxB-6fivA:
15.5		 3cyxB-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.32A 3cyxB-6fivA:
15.5		 3cyxB-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.60A 3d1xA-3slzA:
11.2		 3d1xA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.42A 3d1xB-3slzA:
11.3		 3d1xB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1X_A_ROCA201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.44A 3d1xB-6fivA:
15.6		 3d1xB-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.71A 3d1yA-3slzA:
11.2		 3d1yA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
LEU A  28
ASP A  30
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
None
 0.47A 3d1yB-6fivA:
15.8		 3d1yB-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.64A 3d1zA-3slzA:
11.3		 3d1zA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.56A 3d1zB-3slzA:
11.3		 3d1zB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.46A 3d1zB-3slzA:
11.3		 3d1zB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D1Z_B_017B201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3d1zB-6fivA:
15.7		 3d1zB-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.54A 3d20A-3slzA:
11.2		 3d20A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.41A 3d20A-3slzA:
11.2		 3d20A-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.21A 3d20A-6fivA:
15.6		 3d20A-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.58A 3d20B-3slzA:
11.4		 3d20B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 3d20B-3slzA:
11.4		 3d20B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.42A 3d20B-6fivA:
15.6		 3d20B-6fivA:
30.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ILE A  37
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
 0.59A 3ebzA-6fivA:
15.9		 3ebzA-6fivA:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.45A 3ebzA-6fivA:
15.9		 3ebzA-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.37A 3ebzB-3slzA:
12.2		 3ebzB-3slzA:
25.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3EBZ_B_017B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.45A 3ebzB-6fivA:
15.8		 3ebzB-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.44A 3ekpB-3slzA:
11.6		 3ekpB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.70A 3ekpB-3slzA:
11.6		 3ekpB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 3ekpC-3slzA:
11.5		 3ekpC-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3ekpD-3slzA:
11.5		 3ekpD-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.41A 3ekqA-6fivA:
15.2		 3ekqA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.88A 3ekqB-3slzA:
11.3		 3ekqB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3ektA-3slzA:
11.5		 3ektA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3ektA-6fivA:
15.8		 3ektA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.45A 3ektC-3slzA:
11.7		 3ektC-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.61A 3ektC-3slzA:
11.7		 3ektC-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.48A 3ektD-3slzA:
11.7		 3ektD-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 3ektD-3slzA:
11.7		 3ektD-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.15A 3ektD-6fivA:
15.5		 3ektD-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.53A 3ekvA-3slzA:
11.0		 3ekvA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ekvA-6fivA:
15.2		 3ekvA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.81A 3ekvB-3slzA:
11.1		 3ekvB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ekwA-6fivA:
15.3		 3ekwA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.40A 3ekwB-6fivA:
15.2		 3ekwB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.64A 3ekxA-3slzA:
11.3		 3ekxA-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.18A 3ekxA-6fivA:
15.3		 3ekxA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.73A 3ekxB-3slzA:
11.3		 3ekxB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.65A 3ekyA-6fivA:
15.4		 3ekyA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 8 ASP A  32
GLY A  34
ALA A  35
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.61A 3el0A-3slzA:
11.0		 3el0A-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 8 ASP A  30
GLY A  32
ALA A  33
ASP A  34
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.28A 3el0A-6fivA:
14.8		 3el0A-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.32A 3el1A-3slzA:
11.3		 3el1A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.29A 3el1A-6fivA:
15.2		 3el1A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.46A 3el1A-6fivA:
15.2		 3el1A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.56A 3el1B-3slzA:
11.4		 3el1B-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.60A 3el4A-3slzA:
11.4		 3el4A-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.28A 3el4A-6fivA:
15.3		 3el4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 3el5A-3slzA:
11.0		 3el5A-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.65A 3el5B-3slzA:
11.2		 3el5B-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.52A 3el5B-3slzA:
11.2		 3el5B-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 3el5B-6fivA:
15.0		 3el5B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 8 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.43A 3el9A-6fivA:
15.0		 3el9A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.34A 3el9B-6fivA:
15.4		 3el9B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 3em3A-3slzA:
11.3		 3em3A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3em3B-3slzA:
11.5		 3em3B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.57A 3em4A-6fivA:
15.3		 3em4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_A_DR7A100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.57A 3em4B-6fivA:
15.5		 3em4B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.60A 3em4U-6fivA:
15.5		 3em4U-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.44A 3em6B-3slzA:
11.3		 3em6B-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.76A 3em6B-3slzA:
11.3		 3em6B-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.53A 3gguA-3slzA:
12.1		 3gguA-3slzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 3gguA-3slzA:
12.1		 3gguA-3slzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.13A 3gguA-6fivA:
15.8		 3gguA-6fivA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.23A 3gguB-3slzA:
12.0		 3gguB-3slzA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.14A 3gguB-6fivA:
15.8		 3gguB-6fivA:
27.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.63A 3jvyA-3slzA:
11.1		 3jvyA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 3jvyA-3slzA:
11.1		 3jvyA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.44A 3jvyA-6fivA:
15.4		 3jvyA-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 3jvyB-3slzA:
11.4		 3jvyB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.44A 3jvyB-6fivA:
15.5		 3jvyB-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.48A 3jw2A-3slzA:
11.6		 3jw2A-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.71A 3jw2A-3slzA:
11.6		 3jw2A-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.39A 3k4vA-3slzA:
11.1		 3k4vA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.66A 3k4vC-3slzA:
11.2		 3k4vC-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.51A 3k4vC-6fivA:
15.5		 3k4vC-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.34A 3k4vD-3slzA:
11.1		 3k4vD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K4V_D_ROCD201_3
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.50A 3k4vD-6fivA:
15.4		 3k4vD-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.56A 3lzsA-3slzA:
11.3		 3lzsA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3lzsA-3slzA:
11.3		 3lzsA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3lzsA-6fivA:
15.5		 3lzsA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3lzsA-6fivA:
15.5		 3lzsA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.56A 3lzsB-3slzA:
11.3		 3lzsB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 3lzsB-3slzA:
11.3		 3lzsB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.20A 3lzsB-6fivA:
15.5		 3lzsB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.44A 3lzsB-6fivA:
15.5		 3lzsB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.54A 3lzuA-3slzA:
11.2		 3lzuA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.48A 3lzuA-3slzA:
11.2		 3lzuA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 3lzuA-6fivA:
15.4		 3lzuA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3lzuA-6fivA:
15.4		 3lzuA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.28A 3lzvA-3slzA:
11.2		 3lzvA-3slzA:
28.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LZV_A_017A200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 3lzvA-6fivA:
14.9		 3lzvA-6fivA:
30.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 3lzvB-3slzA:
11.6		 3lzvB-3slzA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.61A 3mwsA-3slzA:
11.9		 3mwsA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.44A 3mwsA-3slzA:
11.9		 3mwsA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 3mwsA-6fivA:
16.1		 3mwsA-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3mwsB-3slzA:
11.7		 3mwsB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 3n3iA-6fivA:
11.0		 3n3iA-6fivA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
VAL A  99
ILE A  37
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
3TL  A 201 ( 4.8A)
 1.21A 3n3iA-6fivA:
11.0		 3n3iA-6fivA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.65A 3ndtA-3slzA:
11.1		 3ndtA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.82A 3ndtB-3slzA:
11.2		 3ndtB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.39A 3ndtB-3slzA:
11.2		 3ndtB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.42A 3ndtC-3slzA:
11.3		 3ndtC-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDT_D_ROCD100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 3ndtC-6fivA:
15.4		 3ndtC-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.73A 3ndtD-3slzA:
11.1		 3ndtD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.54A 3ndtD-3slzA:
11.1		 3ndtD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDT_D_ROCD100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.47A 3ndtD-6fivA:
15.5		 3ndtD-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.34A 3nduA-3slzA:
11.0		 3nduA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_A_ROCA101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduA-6fivA:
15.3		 3nduA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.35A 3nduB-3slzA:
11.2		 3nduB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_A_ROCA101_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.46A 3nduB-6fivA:
15.5		 3nduB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-3.4A)
 0.67A 3nduC-3slzA:
11.2		 3nduC-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_D_ROCD100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduC-6fivA:
15.4		 3nduC-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.33A 3nduD-3slzA:
7.9		 3nduD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDU_D_ROCD100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3nduD-6fivA:
15.1		 3nduD-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.76A 3ndwA-3slzA:
11.2		 3ndwA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.35A 3ndwA-6fivA:
15.2		 3ndwA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 3ndwA-6fivA:
15.2		 3ndwA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDW_A_RITA100_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ARG A  13
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 3ndwB-6fivA:
15.1		 3ndwB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 3ndxA-3slzA:
11.2		 3ndxA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDX_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.37A 3ndxA-6fivA:
15.2		 3ndxA-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NDX_A_RITA100_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.50A 3ndxA-6fivA:
15.2		 3ndxA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.37A 3nu3A-3slzA:
11.1		 3nu3A-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU3_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 3nu3A-6fivA:
15.5		 3nu3A-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.45A 3nu3B-3slzA:
11.3		 3nu3B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-4.0A)
 0.87A 3nu3B-3slzA:
11.3		 3nu3B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU3_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.25A 3nu3B-6fivA:
15.6		 3nu3B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU4_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.93A 3nu4A-6fivA:
15.4		 3nu4A-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.28A 3nu4B-3slzA:
11.4		 3nu4B-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU4_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 3nu4B-6fivA:
15.6		 3nu4B-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.67A 3nu5A-3slzA:
11.1		 3nu5A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.38A 3nu5A-3slzA:
11.1		 3nu5A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 3nu5B-3slzA:
11.3		 3nu5B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-4.0A)
 0.79A 3nu5B-3slzA:
11.3		 3nu5B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU5_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.35A 3nu5B-6fivA:
15.6		 3nu5B-6fivA:
31.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU5_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.26A 3nu5B-6fivA:
15.6		 3nu5B-6fivA:
31.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.67A 3nu6A-3slzA:
11.2		 3nu6A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3nu6B-3slzA:
11.4		 3nu6B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU6_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 3nu6B-6fivA:
15.6		 3nu6B-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 8 ASP A  32
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.45A 3nu9A-3slzA:
11.1		 3nu9A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 8 ASP A  32
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.55A 3nu9A-3slzA:
11.1		 3nu9A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3nu9B-3slzA:
11.3		 3nu9B-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU9_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.15A 3nu9B-6fivA:
15.5		 3nu9B-6fivA:
30.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NU9_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.48A 3nu9B-6fivA:
15.5		 3nu9B-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.88A 3nujA-3slzA:
11.2		 3nujA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.46A 3nujB-3slzA:
11.4		 3nujB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NUJ_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.20A 3nujB-6fivA:
15.6		 3nujB-6fivA:
30.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 3nuoB-3slzA:
11.4		 3nuoB-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NUO_B_478B478_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.24A 3nuoB-6fivA:
15.5		 3nuoB-6fivA:
31.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_1
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 ASP A  32
GLY A  34
ALA A  35
GLY A  56
LEU A  92
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.28A 3ogpA-3slzA:
12.0		 3ogpA-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_A_017A200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.60A 3ogpA-6fivA:
21.8		 3ogpA-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_A_017A200_2
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
LEU A  92
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.42A 3ogpB-3slzA:
12.0		 3ogpB-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_A_017A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ILE A  35
MET A  56
GLY A  58
VAL A  99
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
None
3TL  A 201 (-4.8A)
 0.54A 3ogpB-6fivA:
22.0		 3ogpB-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
GLY A  56
LEU A  92
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.47A 3ogpA-3slzA:
12.0		 3ogpA-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_B_017B200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ILE A  35
MET A  56
GLY A  58
VAL A  99
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
None
3TL  A 201 (-4.8A)
 0.64A 3ogpA-6fivA:
21.7		 3ogpA-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_2
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 ASP A  32
GLY A  34
ALA A  35
GLY A  56
LEU A  92
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.21A 3ogpB-3slzA:
12.0		 3ogpB-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGP_B_017B200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.46A 3ogpB-6fivA:
22.0		 3ogpB-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
LEU A  92
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.43A 3ogqA-3slzA:
11.8		 3ogqA-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.52A 3ogqA-6fivA:
21.4		 3ogqA-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
LEU A  92
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.6A)
 0.31A 3ogqB-3slzA:
12.0		 3ogqB-3slzA:
26.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
MET A  56
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-4.7A)
3TL  A 201 (-3.4A)
 0.65A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-3.4A)
 0.48A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OGQ_A_AB1A200_2
(FIV PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  35
GLY A  58
LEU A 101
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.3A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.8A)
 0.36A 3ogqB-6fivA:
21.5		 3ogqB-6fivA:
95.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.67A 3oxcA-3slzA:
11.0		 3oxcA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXC_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.39A 3oxcA-6fivA:
14.9		 3oxcA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.35A 3oxcB-3slzA:
11.0		 3oxcB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXC_A_ROCA401_3
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.47A 3oxcB-6fivA:
15.2		 3oxcB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 3oxvA-3slzA:
11.6		 3oxvA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.33A 3oxvA-6fivA:
15.6		 3oxvA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.48A 3oxvA-6fivA:
15.6		 3oxvA-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.75A 3oxvB-3slzA:
11.3		 3oxvB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.56A 3oxvC-3slzA:
11.4		 3oxvC-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.34A 3oxvC-6fivA:
15.7		 3oxvC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.29A 3oxvC-6fivA:
15.7		 3oxvC-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.80A 3oxvD-3slzA:
11.5		 3oxvD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 3oxwA-3slzA:
11.4		 3oxwA-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.31A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.21A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.55A 3oxwA-6fivA:
15.7		 3oxwA-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3oxwB-3slzA:
11.6		 3oxwB-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.63A 3oxwB-3slzA:
11.6		 3oxwB-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.22A 3oxwB-6fivA:
15.9		 3oxwB-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.25A 3oxwC-3slzA:
11.6		 3oxwC-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 1.30A 3oxwC-6fivA:
15.7		 3oxwC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.55A 3oxwC-6fivA:
15.7		 3oxwC-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3oxwD-3slzA:
11.3		 3oxwD-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.69A 3oxwD-3slzA:
11.3		 3oxwD-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXW_D_017D200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
None
 0.65A 3oxwD-6fivA:
15.8		 3oxwD-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.61A 3oxxA-3slzA:
11.2		 3oxxA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 3oxxA-3slzA:
11.2		 3oxxA-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.30A 3oxxA-6fivA:
15.4		 3oxxA-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.38A 3oxxB-6fivA:
15.4		 3oxxB-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_A_DR7A100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.56A 3oxxB-6fivA:
15.4		 3oxxB-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.34A 3oxxC-3slzA:
11.0		 3oxxC-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.30A 3oxxC-6fivA:
15.2		 3oxxC-6fivA:
30.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.53A 3oxxC-6fivA:
15.2		 3oxxC-6fivA:
30.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 3oy4A-3slzA:
11.1		 3oy4A-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.76A 3oy4A-6fivA:
15.0		 3oy4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.72A 3oy4A-6fivA:
15.0		 3oy4A-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 3oy4B-3slzA:
11.2		 3oy4B-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.47A 3oy4B-6fivA:
15.1		 3oy4B-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.55A 3pwmA-3slzA:
11.1		 3pwmA-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 3pwmA-3slzA:
11.1		 3pwmA-3slzA:
25.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWM_B_017B402_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.47A 3pwmA-6fivA:
15.4		 3pwmA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.47A 3pwmB-3slzA:
11.3		 3pwmB-3slzA:
25.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWM_B_017B402_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.48A 3pwmB-6fivA:
15.7		 3pwmB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.64A 3pwrA-3slzA:
11.1		 3pwrA-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.27A 3pwrA-3slzA:
11.1		 3pwrA-3slzA:
25.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWR_A_ROCA401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3pwrA-6fivA:
15.3		 3pwrA-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 3pwrB-3slzA:
11.2		 3pwrB-3slzA:
25.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3PWR_A_ROCA401_3
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 3pwrB-6fivA:
15.6		 3pwrB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.40A 3s43B-3slzA:
11.4		 3s43B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 3s43B-6fivA:
15.4		 3s43B-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.30A 3s45B-3slzA:
12.2		 3s45B-3slzA:
25.71
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S45_B_478B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.31A 3s45B-6fivA:
15.8		 3s45B-6fivA:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S45_B_478B201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.55A 3s45B-6fivA:
15.8		 3s45B-6fivA:
31.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.38A 3s53A-6fivA:
15.2		 3s53A-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.39A 3s53B-6fivA:
15.5		 3s53B-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.61A 3s54A-3slzA:
11.2		 3s54A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.55A 3s54A-3slzA:
11.2		 3s54A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.70A 3s54B-3slzA:
11.3		 3s54B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.36A 3s54B-3slzA:
11.3		 3s54B-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_A_ROCA201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.44A 3s56A-6fivA:
14.8		 3s56A-6fivA:
29.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SM2_A_478A126_2
(GAG-PRO-POL
POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		11 / 11 ASP A  32
ALA A  35
HIS A  37
VAL A  39
VAL A  54
GLY A  56
ALA A  57
LEU A  83
PRO A  89
TYR A  90
LEU A  92
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
3TL  A 126 ( 4.1A)
None
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
3TL  A 126 (-3.6A)
None
3TL  A 126 (-4.0A)
3TL  A 126 (-4.4A)
3TL  A 126 (-4.6A)
 0.32A 3sm2B-3slzA:
21.5		 3sm2B-3slzA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_A_TPVA100_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.38A 3spkA-6fivA:
15.8		 3spkA-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
LEU A  28
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.38A 3spkB-6fivA:
15.8		 3spkB-6fivA:
29.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 7 ASP A  32
GLY A  34
ALA A  35
VAL A  39
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
 0.31A 3t3cA-3slzA:
11.5		 3t3cA-3slzA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 7 ASP A  30
GLY A  32
ALA A  33
ASP A  34
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.14A 3t3cA-6fivA:
15.2		 3t3cA-6fivA:
28.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.33A 3tkgA-3slzA:
11.3		 3tkgA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_B_ROCB801_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 3tkgA-6fivA:
13.8		 3tkgA-6fivA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.33A 3tkgB-3slzA:
11.2		 3tkgB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_B_ROCB801_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.40A 3tkgB-6fivA:
15.5		 3tkgB-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_C_ROCC901_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.52A 3tkgC-6fivA:
15.2		 3tkgC-6fivA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 3tkgD-3slzA:
11.0		 3tkgD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKG_C_ROCC901_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 3tkgD-6fivA:
15.5		 3tkgD-6fivA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 3tkwA-3slzA:
11.3		 3tkwA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKW_B_017B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.20A 3tkwA-6fivA:
15.6		 3tkwA-6fivA:
30.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TKW_B_017B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.45A 3tkwA-6fivA:
15.6		 3tkwA-6fivA:
30.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.76A 3tl9A-3slzA:
11.2		 3tl9A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 3tl9A-3slzA:
11.2		 3tl9A-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 3ttpA-6fivA:
15.8		 3ttpA-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 3ttpB-6fivA:
15.8		 3ttpB-6fivA:
27.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.28A 3u7sA-3slzA:
11.9		 3u7sA-3slzA:
26.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 3u7sA-6fivA:
15.8		 3u7sA-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_2
(POL POLYPROTEIN)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 3u7sB-6fivA:
16.1		 3u7sB-6fivA:
29.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.28A 3ucbA-3slzA:
12.2		 3ucbA-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.31A 3ucbA-6fivA:
16.0		 3ucbA-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ILE A  37
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
None
 0.64A 3ucbA-6fivA:
16.0		 3ucbA-6fivA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.43A 3ucbB-3slzA:
11.3		 3ucbB-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.36A 3ucbB-6fivA:
15.9		 3ucbB-6fivA:
32.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UCB_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ILE A  37
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 ( 4.8A)
None
 0.70A 3ucbB-6fivA:
15.9		 3ucbB-6fivA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.89A 3ufnA-3slzA:
11.9		 3ufnA-3slzA:
26.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.48A 3ufnA-3slzA:
11.9		 3ufnA-3slzA:
26.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UFN_A_ROCA401_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.34A 3ufnA-6fivA:
15.8		 3ufnA-6fivA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
ALA A  35
VAL A  39
LEU A  83
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
None
 0.50A 3wsjA-3slzA:
10.3		 3wsjA-3slzA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
 0.58A 3wsjA-6fivA:
12.0		 3wsjA-6fivA:
26.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 7 LEU A  30
ASP A  32
ALA A  35
VAL A  54
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
 0.55A 3wsjB-3slzA:
10.1		 3wsjB-3slzA:
27.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 4dqbA-3slzA:
11.0		 4dqbA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.72A 4dqbA-3slzA:
11.0		 4dqbA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.59A 4dqbB-3slzA:
11.0		 4dqbB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.67A 4dqbB-6fivA:
15.3		 4dqbB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.54A 4dqcB-3slzA:
11.2		 4dqcB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 4dqcB-6fivA:
15.4		 4dqcB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.83A 4dqeA-3slzA:
11.1		 4dqeA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.70A 4dqeA-6fivA:
15.2		 4dqeA-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 4dqeB-3slzA:
11.1		 4dqeB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.67A 4dqeB-6fivA:
15.3		 4dqeB-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.44A 4dqfA-3slzA:
10.6		 4dqfA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.75A 4dqfA-3slzA:
10.6		 4dqfA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.27A 4dqfB-3slzA:
10.9		 4dqfB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.57A 4dqhA-3slzA:
11.0		 4dqhA-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
LEU A  28
ASP A  30
ALA A  33
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
None
 0.76A 4dqhA-6fivA:
15.1		 4dqhA-6fivA:
28.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 4dqhB-3slzA:
11.1		 4dqhB-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.63A 4dqhB-6fivA:
15.3		 4dqhB-6fivA:
28.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 4hlaA-3slzA:
11.1		 4hlaA-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 4hlaA-6fivA:
15.5		 4hlaA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.58A 4hlaA-6fivA:
15.5		 4hlaA-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.29A 4hlaB-3slzA:
11.1		 4hlaB-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 4hlaB-6fivA:
15.5		 4hlaB-6fivA:
29.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 LEU A  28
ASP A  30
GLY A  32
ALA A  33
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
None
 0.56A 4hlaB-6fivA:
15.5		 4hlaB-6fivA:
29.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4J5J_B_478B401_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.76A 4j5jB-6fivA:
16.0		 4j5jB-6fivA:
32.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.46A 4jecB-3slzA:
11.2		 4jecB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JEC_B_478B401_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.29A 4jecB-6fivA:
15.4		 4jecB-6fivA:
30.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 4ll3B-3slzA:
11.2		 4ll3B-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.16A 4ll3B-6fivA:
15.5		 4ll3B-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.43A 4ll3A-3slzA:
11.2		 4ll3A-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.16A 4ll3A-6fivA:
15.5		 4ll3A-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 ARG A  13
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.61A 4ll3B-6fivA:
15.5		 4ll3B-6fivA:
28.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.34A 4njtA-3slzA:
11.3		 4njtA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.67A 4njtA-3slzA:
11.3		 4njtA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 4njtB-3slzA:
11.9		 4njtB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJT_B_017B101_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.17A 4njtB-6fivA:
15.9		 4njtB-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.44A 4njtC-3slzA:
11.4		 4njtC-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.69A 4njtC-3slzA:
11.4		 4njtC-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
 0.31A 4njtD-3slzA:
11.8		 4njtD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.58A 4njuA-3slzA:
11.3		 4njuA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.68A 4njuA-3slzA:
11.3		 4njuA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_A_TPVA500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.42A 4njuA-6fivA:
15.4		 4njuA-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 4njuB-3slzA:
11.7		 4njuB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.72A 4njuB-3slzA:
11.7		 4njuB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_A_TPVA500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.42A 4njuB-6fivA:
15.9		 4njuB-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.59A 4njuC-3slzA:
11.2		 4njuC-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.69A 4njuC-3slzA:
11.2		 4njuC-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_C_TPVC500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.44A 4njuC-6fivA:
15.4		 4njuC-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 4njuD-3slzA:
11.7		 4njuD-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.71A 4njuD-3slzA:
11.7		 4njuD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJU_C_TPVC500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ARG A  13
LEU A  28
ASP A  30
ALA A  33
GLY A  58
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.42A 4njuD-6fivA:
15.9		 4njuD-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.50A 4njvA-3slzA:
11.4		 4njvA-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_A_RITA500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.27A 4njvA-6fivA:
15.5		 4njvA-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
GLY A  34
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.72A 4njvB-3slzA:
11.7		 4njvB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_A_RITA500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
ASP A  30
GLY A  32
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.22A 4njvB-6fivA:
15.9		 4njvB-6fivA:
31.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_D_RITD500_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 11 ARG A  13
ASP A  30
GLY A  32
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.27A 4njvC-6fivA:
15.5		 4njvC-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_D_RITD500_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.59A 4njvD-3slzA:
11.7		 4njvD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4NJV_D_RITD500_2
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.16A 4njvD-6fivA:
15.9		 4njvD-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 6 MET A  56
ILE A  18
ILE A  25
VAL A  20
 3TL  A 201 (-4.7A)
None
None
None
 1.02A 4olmA-6fivA:
undetectable		 4olmA-6fivA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.26A 4q1wA-3slzA:
11.3		 4q1wA-3slzA:
25.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1W_A_017A104_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.45A 4q1wA-6fivA:
15.2		 4q1wA-6fivA:
30.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.81A 4q1wB-3slzA:
11.1		 4q1wB-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.26A 4q1xA-3slzA:
11.3		 4q1xA-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 4q1xB-3slzA:
11.2		 4q1xB-3slzA:
25.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.26A 4q1yA-3slzA:
11.4		 4q1yA-3slzA:
25.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1Y_A_017A106_1
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		8 / 10 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.53A 4q1yA-6fivA:
15.3		 4q1yA-6fivA:
30.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
ALA A  33
ILE A  37
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
None
 0.60A 4q1yB-6fivA:
15.3		 4q1yB-6fivA:
30.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QGI_A_ROCA101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 11 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.52A 4qgiA-6fivA:
15.2		 4qgiA-6fivA:
30.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QGI_A_ROCA101_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.67A 4qgiB-3slzA:
11.2		 4qgiB-3slzA:
26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.87A 4rvjA-3slzA:
11.1		 4rvjA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 4rvjB-3slzA:
11.9		 4rvjB-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.27A 4rvjB-6fivA:
15.8		 4rvjB-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.93A 4rvjC-3slzA:
11.1		 4rvjC-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 11 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 4rvjC-3slzA:
11.1		 4rvjC-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 9 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.52A 4rvjD-3slzA:
11.9		 4rvjD-3slzA:
25.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.28A 4rvjD-6fivA:
15.8		 4rvjD-6fivA:
31.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.33A 5e5jA-3slzA:
11.5		 5e5jA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.33A 5e5jA-6fivA:
15.7		 5e5jA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.76A 5e5jB-3slzA:
11.3		 5e5jB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.61A 5e5kA-3slzA:
11.5		 5e5kA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.34A 5e5kA-3slzA:
11.5		 5e5kA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.28A 5e5kB-3slzA:
11.2		 5e5kB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.32A 5e5kB-6fivA:
15.4		 5e5kB-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.11A 5ewzB-6fivA:
undetectable		 5ewzB-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_2
(PROTEASE E35D-DRV)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		4 / 7 GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 5kqyB-6fivA:
15.7		 5kqyB-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 9 LEU A  30
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.59A 5kr0B-3slzA:
11.4		 5kr0B-3slzA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 9 LEU A  28
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.49A 5kr0B-6fivA:
15.7		 5kr0B-6fivA:
29.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_2
(PROTEASE PR5-DRV)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		4 / 8 GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.66A 5kr1B-3slzA:
11.1		 5kr1B-3slzA:
27.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.01A 5m35B-6fivA:
undetectable		 5m35B-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.97A 5m36A-6fivA:
undetectable		 5m36A-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 CYH A  90
MET A  56
ASN A  55
 None
3TL  A 201 (-4.7A)
None
 1.29A 5qh8A-6fivA:
undetectable		 5qh8A-6fivA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.56A 5t2zA-3slzA:
11.4		 5t2zA-3slzA:
29.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 5t2zA-3slzA:
11.4		 5t2zA-3slzA:
29.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5T2Z_B_017B201_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.19A 5t2zA-6fivA:
15.7		 5t2zA-6fivA:
30.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.49A 5t2zB-3slzA:
11.4		 5t2zB-3slzA:
29.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T2Z_B_017B201_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.65A 5t2zB-3slzA:
11.4		 5t2zB-3slzA:
29.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.32A 5t8hA-3slzA:
11.6		 5t8hA-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
ILE A  37
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 ( 4.8A)
3TL  A 201 (-3.4A)
 0.38A 5t8hA-6fivA:
15.7		 5t8hA-6fivA:
29.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.79A 5t8hB-3slzA:
11.2		 5t8hB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_2
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  54
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.3A)
3TL  A 126 (-3.4A)
 0.54A 5t8hB-3slzA:
11.2		 5t8hB-3slzA:
25.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-4.0A)
 0.73A 6dgxA-3slzA:
11.2		 6dgxA-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.60A 6dgxA-3slzA:
11.2		 6dgxA-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.21A 6dgxA-6fivA:
15.4		 6dgxA-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.50A 6dgxA-6fivA:
15.4		 6dgxA-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
ALA A  35
VAL A  39
LEU A  83
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
None
3TL  A 126 (-4.0A)
 0.66A 6dgxB-3slzA:
11.1		 6dgxB-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.38A 6dgxB-3slzA:
11.1		 6dgxB-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
LEU A  83
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
None
 0.62A 6dgxB-3slzA:
11.1		 6dgxB-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
ALA A  33
GLY A  58
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.43A 6dgxB-6fivA:
15.2		 6dgxB-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
3TL  A 126 (-3.4A)
 0.31A 6dh0A-3slzA:
11.1		 6dh0A-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.26A 6dh0A-6fivA:
15.4		 6dh0A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.49A 6dh0A-6fivA:
15.4		 6dh0A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.42A 6dh0B-3slzA:
11.2		 6dh0B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
LEU A  83
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
None
3TL  A 126 (-4.0A)
 0.67A 6dh0B-3slzA:
11.2		 6dh0B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.58A 6dh3A-3slzA:
11.1		 6dh3A-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.25A 6dh3A-6fivA:
15.4		 6dh3A-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.56A 6dh3B-3slzA:
10.8		 6dh3B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.35A 6dh3B-3slzA:
10.8		 6dh3B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH3_A_017A101_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.25A 6dh3B-6fivA:
15.3		 6dh3B-6fivA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.61A 6dh6A-3slzA:
11.1		 6dh6A-3slzA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  59
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.3A)
 0.34A 6dh6A-6fivA:
15.4		 6dh6A-6fivA:
31.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_0
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  59
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-4.3A)
None
 0.56A 6dh6A-6fivA:
15.4		 6dh6A-6fivA:
31.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
LEU A  83
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
None
3TL  A 126 (-4.0A)
 0.61A 6dh6B-3slzA:
11.1		 6dh6B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.39A 6dh6B-3slzA:
11.1		 6dh6B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
LEU A  83
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
None
 0.60A 6dh6B-3slzA:
11.1		 6dh6B-3slzA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DH6_A_017A104_1
(PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
 0.27A 6dh6B-6fivA:
15.2		 6dh6B-6fivA:
31.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.49A 6difA-6fivA:
15.3		 6difA-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.51A 6difB-3slzA:
11.2		 6difB-3slzA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
GLY A  34
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
None
3TL  A 126 (-4.0A)
 0.73A 6difB-3slzA:
11.2		 6difB-3slzA:
23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
GLY A  32
ALA A  33
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.4A)
None
 0.45A 6difB-6fivA:
15.5		 6difB-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.57A 6dilA-3slzA:
11.1		 6dilA-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 LEU A  30
ASP A  32
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.63A 6dilA-3slzA:
11.1		 6dilA-3slzA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		7 / 12 ARG A  13
LEU A  28
ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 None
None
3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.59A 6dilA-6fivA:
15.3		 6dilA-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.53A 6dilB-3slzA:
11.3		 6dilB-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		6 / 12 LEU A  30
ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 None
3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.62A 6dilB-3slzA:
11.3		 6dilB-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.56A 6dj1A-3slzA:
11.1		 6dj1A-3slzA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.64A 6dj1A-3slzA:
11.1		 6dj1A-3slzA:
23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.53A 6dj1A-6fivA:
15.4		 6dj1A-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.58A 6dj1B-3slzA:
11.0		 6dj1B-3slzA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.73A 6dj1B-3slzA:
11.0		 6dj1B-3slzA:
23.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.75A 6dj1B-6fivA:
15.6		 6dj1B-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 12 ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.24A 6dj1B-6fivA:
15.6		 6dj1B-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 10 ASP A  32
ALA A  35
VAL A  39
GLY A  56
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
3TL  A 126 (-4.0A)
 0.86A 6dj2A-3slzA:
11.1		 6dj2A-3slzA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_0
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		5 / 10 ASP A  30
ALA A  33
ASP A  34
GLY A  58
VAL A  99
 3TL  A 201 (-3.5A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
None
 0.66A 6dj2A-6fivA:
15.4		 6dj2A-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
GLY A  56
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-3.4A)
 0.55A 6dj2B-3slzA:
11.1		 6dj2B-3slzA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 3slz GAG-PRO-POL
POLYPROTEIN
(Murine
leukemia
virus) 		5 / 12 ASP A  32
GLY A  34
ALA A  35
VAL A  39
PRO A  89
 3TL  A 126 (-2.4A)
3TL  A 126 (-3.1A)
3TL  A 126 ( 4.0A)
None
3TL  A 126 (-4.0A)
 0.73A 6dj2B-3slzA:
11.1		 6dj2B-3slzA:
24.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
GLY A  58
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
3TL  A 201 (-3.4A)
 0.56A 6dj2B-6fivA:
15.6		 6dj2B-6fivA:
30.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		6 / 12 ARG A  13
ASP A  30
GLY A  32
ALA A  33
ASP A  34
VAL A  99
 None
3TL  A 201 (-3.5A)
3TL  A 201 (-3.4A)
3TL  A 201 (-4.0A)
3TL  A 201 (-3.9A)
None
 0.68A 6dj2B-6fivA:
15.6		 6dj2B-6fivA:
30.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.99A 6fn9A-6fivA:
undetectable		 6fn9A-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 1.03A 6fnaB-6fivA:
undetectable		 6fnaB-6fivA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 6fiv RETROPEPSIN
(Feline
immunodeficiency
virus) 		3 / 3 MET A  56
GLN A  54
ARG A  64
 3TL  A 201 (-4.7A)
3TL  A 201 ( 4.1A)
None
 0.98A 6fnbA-6fivA:
undetectable		 6fnbA-6fivA:
18.26