SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3S5'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4woe TAUROCYAMINE KINASE
(Schistosoma
mansoni) 		4 / 6 SER A 482
ARG A 589
GLU A 585
GLU A 584
 ADP  A 802 (-2.5A)
NO3  A 808 ( 3.0A)
3S5  A 804 ( 2.7A)
MG  A 805 (-3.6A)
 1.16A 3k9fA-4woeA:
2.4
3k9fB-4woeA:
2.4
3k9fD-4woeA:
undetectable		 3k9fA-4woeA:
20.35
3k9fB-4woeA:
20.35
3k9fD-4woeA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KHP_A_PARA1606_1
(16S RIBOSOMAL RNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 4woe TAUROCYAMINE KINASE
(Schistosoma
mansoni) 		3 / 3 TYR A 447
ARG A 690
SER A 633
 None
None
3S5  A 804 ( 4.0A)
 1.08A 4khpI-4woeA:
undetectable
4khpJ-4woeA:
undetectable		 4khpI-4woeA:
11.32
4khpJ-4woeA:
9.65