SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3QL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 4wlk YUIC
(Bacillus
subtilis) 		5 / 12 THR A 137
ALA A 127
THR A 125
ALA A 150
THR A 112
 None
3QL  A 301 (-3.6A)
None
None
None
 1.44A 5d0xH-4wlkA:
undetectable
5d0xI-4wlkA:
undetectable		 5d0xH-4wlkA:
20.76
5d0xI-4wlkA:
23.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 4wlk YUIC
(Bacillus
subtilis) 		5 / 12 ILE A 156
GLY A 153
ALA A 127
TYR A  93
LEU A 161
 None
3QL  A 301 (-3.6A)
3QL  A 301 (-3.6A)
3QL  A 301 (-3.6A)
None
 1.17A 5hw4A-4wlkA:
undetectable		 5hw4A-4wlkA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K4P_A_SORA611_0
(PROBABLE
PHOSPHATIDYLETHANOLA
MINE TRANSFERASE
MCR-1)		 4wlk YUIC
(Bacillus
subtilis) 		4 / 6 THR A 100
SER A  99
TYR A  93
GLY A  96
 3QL  A 301 (-3.5A)
3QL  A 301 (-4.6A)
3QL  A 301 (-3.6A)
None
 0.77A 5k4pA-4wlkA:
undetectable		 5k4pA-4wlkA:
21.07