SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3PY'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA1_1 (CES1 PROTEIN)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	6 / 12	ALA A  10 GLY A  46 GLY A  45 LEU A  12 LEU A  13 LEU A  22	None 3PY  A 802 (-3.5A) None None None None	1.36A	1ya4A-1hl2A: undetectable	1ya4A-1hl2A: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM8_A_ACAA512_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	5 / 10	TYR A  43 TYR A 137 SER A  47 GLY A 189 ILE A 206	3PY  A 802 (-4.6A) 3PY  A 802 (-4.0A) 3PY  A 802 (-3.2A) None 3PY  A 802 ( 4.9A)	1.28A	2zm8A-1hl2A: 0.0	2zm8A-1hl2A: 23.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4BWL_C_MN9C1297_0 (N-ACETYLNEURAMINATE LYASE)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	9 / 10	ILE A 139 THR A 167 GLY A 189 TYR A 190 ASP A 191 GLU A 192 GLY A 207 SER A 208 PHE A 252	3PY  A 802 ( 4.9A) 3PY  A 802 (-3.6A) None None None None None None None	0.39A	4bwlC-1hl2A: 52.2	4bwlC-1hl2A: 97.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UBE_A_2FAA401_2 (ADENOSINE KINASE)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	4 / 4	ALA A  10 VAL A  44 GLY A  49 THR A  48	None None None 3PY  A 802 (-3.4A)	0.96A	4ubeA-1hl2A: 2.9	4ubeA-1hl2A: 23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_A_P06A801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	4 / 7	ILE A 206 GLY A 205 PHE A  33 ASP A  40	3PY  A 802 ( 4.9A) None None None	0.73A	5hieA-1hl2A: undetectable	5hieA-1hl2A: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	4 / 7	ILE A 206 GLY A 205 PHE A  33 ASP A  40	3PY  A 802 ( 4.9A) None None None	0.73A	5hieB-1hl2A: undetectable	5hieB-1hl2A: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_D_P06D801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	1hl2	N-ACETYLNEURAMINATE LYASE SUBUNIT (Escherichia coli)	4 / 8	ILE A 206 GLY A 205 PHE A  33 ASP A  40	3PY  A 802 ( 4.9A) None None None	0.75A	5hieD-1hl2A: undetectable	5hieD-1hl2A: 22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IEO_A_VDYA206_2 (CDL2.3A)	4dqd	EXTRACELLULAR LIGAND-BINDING RECEPTOR (Rhodopseudomonas palustris)	4 / 8	ILE A  55 PRO A  52 ILE A  91 LEU A 323	None 3PY  A 404 (-3.9A) None None	1.01A	5ieoA-4dqdA: undetectable	5ieoA-4dqdA: 16.52