SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3NI'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3usc HYDROGENASE-1 LARGE
CHAIN
(Escherichia
coli) 		4 / 6 CYH L  79
VAL L  78
HIS L  83
CYH L 579
 FCO  L 601 ( 2.3A)
3NI  L 602 ( 4.8A)
FCO  L 601 (-3.9A)
FCO  L 601 ( 2.3A)
 1.42A 1ekjG-3uscL:
undetectable
1ekjH-3uscL:
undetectable		 1ekjG-3uscL:
18.07
1ekjH-3uscL:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P9G_A_ACTA42_0
(EAFP 2)		 3usc HYDROGENASE-1 LARGE
CHAIN
(Escherichia
coli) 		3 / 3 CYH L  79
ARG L 509
CYH L  76
 FCO  L 601 ( 2.3A)
FCO  L 601 (-4.2A)
3NI  L 602 (-2.2A)
 1.39A 1p9gA-3uscL:
undetectable		 1p9gA-3uscL:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_A_IL2A901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 3usc HYDROGENASE-1 LARGE
CHAIN
(Escherichia
coli) 		5 / 12 LEU L 114
THR L 532
THR L 533
ILE L 398
VAL L  78
 None
FCO  L 601 (-3.7A)
None
None
3NI  L 602 ( 4.8A)
 1.20A 3sp9A-3uscL:
undetectable		 3sp9A-3uscL:
17.24