SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3NF'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_A_FCNA1199_1
(EPOXIDASE)
3nfz ASPARTOACYLASE-2
(Mus
musculus)
5 / 9 TYR A 287
ASN A  70
HIS A  21
GLU A  24
HIS A 116
3NF  A 322 (-4.4A)
3NF  A 322 (-3.9A)
ZN  A 319 ( 3.4A)
ZN  A 319 ( 2.1A)
ZN  A 319 (-3.4A)
1.41A 2bnnA-3nfzA:
undetectable
2bnnB-3nfzA:
0.0
2bnnA-3nfzA:
23.31
2bnnB-3nfzA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)
3nfz ASPARTOACYLASE-2
(Mus
musculus)
4 / 8 ILE A 127
PHE A 281
PRO A 150
PHE A 251
3NF  A 322 (-4.0A)
None
None
None
1.01A 5x23A-3nfzA:
undetectable
5x23A-3nfzA:
21.49