SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3LD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifA-3w4kA:
53.9		 1kifA-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.33A 1kifA-3w4kA:
53.9		 1kifA-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifB-3w4kA:
53.9		 1kifB-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.32A 1kifB-3w4kA:
53.9		 1kifB-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifC-3w4kA:
53.8		 1kifC-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.33A 1kifC-3w4kA:
53.8		 1kifC-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifD-3w4kA:
53.8		 1kifD-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.33A 1kifD-3w4kA:
53.8		 1kifD-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifE-3w4kA:
53.9		 1kifE-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.33A 1kifE-3w4kA:
53.9		 1kifE-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifF-3w4kA:
53.9		 1kifF-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.32A 1kifF-3w4kA:
53.9		 1kifF-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.79A 1kifG-3w4kA:
53.9		 1kifG-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.32A 1kifG-3w4kA:
53.9		 1kifG-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.80A 1kifH-3w4kA:
53.9		 1kifH-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.32A 1kifH-3w4kA:
53.9		 1kifH-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.83A 1ve9A-3w4kA:
53.0		 1ve9A-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.34A 1ve9A-3w4kA:
53.0		 1ve9A-3w4kA:
84.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		5 / 6 LEU A 215
TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-4.1A)
3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.35A 2du8A-3w4kA:
55.2		 2du8A-3w4kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DU8_A_BEZA352_0
(D-AMINO-ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 6 TYR A 224
TYR A 228
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.74A 2du8A-3w4kA:
55.2		 2du8A-3w4kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DU8_B_BEZB1352_0
(D-AMINO-ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		5 / 6 LEU A 215
TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-4.1A)
3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.34A 2du8B-3w4kA:
55.5		 2du8B-3w4kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		5 / 5 TYR A 224
TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.6A)
3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.68A 2du8G-3w4kA:
55.1		 2du8G-3w4kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 5 TYR A 228
ILE A 230
ARG A 283
GLY A 313
 3LD  A 402 (-3.8A)
None
3LD  A 402 (-3.7A)
3LD  A 402 ( 3.6A)
 0.29A 2du8J-3w4kA:
54.9		 2du8J-3w4kA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 3w4k D-AMINO-ACID OXIDASE
(Homo
sapiens) 		4 / 8 LEU A 215
ILE A 230
ALA A  49
PRO A 105
 3LD  A 402 (-4.1A)
None
FAD  A 401 ( 4.0A)
None
 0.92A 5m0oC-3w4kA:
undetectable		 5m0oC-3w4kA:
20.38