SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3DY'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans)
4 / 7 ASP A 231
GLN A 259
TYR A 233
PRO A 232
3DY  A 521 (-2.6A)
None
None
None
1.20A 3l2vA-4u6dA:
undetectable
3l2vA-4u6dA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHD_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans)
5 / 12 LEU A 368
SER A  86
PRO A 113
ASN A 364
HIS A 230
None
None
None
None
3DY  A 521 ( 3.7A)
1.49A 5uhdC-4u6dA:
0.7
5uhdC-4u6dA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_A_ACTA816_0
(UNCHARACTERIZED
PROTEIN)
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans)
3 / 3 ARG A  88
ARG A 107
ASP A 127
3DY  A 521 (-4.0A)
None
None
0.60A 6d8pA-4u6dA:
undetectable
6d8pA-4u6dA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans)
3 / 3 ASN A 218
PRO A 195
GLN A 181
None
None
3DY  A 521 (-3.2A)
0.59A 6jnhA-4u6dA:
undetectable
6jnhA-4u6dA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
4u6d CONSERVED
HYPOTHETICAL
PERIPLASMIC PROTEIN

(Zobellia
galactanivorans)
3 / 3 ASN A 218
PRO A 195
GLN A 181
None
None
3DY  A 521 (-3.2A)
0.58A 6jogA-4u6dA:
undetectable
6jogA-4u6dA:
16.43