SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3CU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMA_A_SAMA375_0
(PROBABLE TRNA
(5-METHYLAMINOMETHYL
-2-THIOURIDYLATE)-ME
THYLTRANSFERASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 GLY A 556
ASP A 542
ASN A 543
GLY A 569
PHE A 575
 None
3CU  A1001 ( 2.5A)
None
None
3CU  A1001 (-4.5A)
 1.21A 2hmaA-3cttA:
undetectable		 2hmaA-3cttA:
18.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		8 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ASP A 542
PHE A 575
ALA A 576
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-3.9A)
 1.44A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		12 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
ASP A 542
PHE A 575
ALA A 576
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-3.9A)
 0.33A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 327
ILE A 364
ASP A 571
PHE A 575
ALA A 576
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 4.8A)
3CU  A1001 (-4.5A)
None
 1.38A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.17A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 364
ARG A 598
ASP A 571
PHE A 575
ALA A 576
 3CU  A1001 (-4.5A)
3CU  A1001 ( 4.7A)
3CU  A1001 ( 4.8A)
3CU  A1001 (-4.5A)
None
 1.43A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QMJ_A_ACRA1001_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 6 THR A 205
TYR A 299
TRP A 441
MET A 444
TRP A 539
THR A 544
 None
3CU  A1001 (-3.6A)
3CU  A1001 (-4.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
None
 0.26A 2qmjA-3cttA:
61.8		 2qmjA-3cttA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ASP A 443
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.51A 2x2iA-3cttA:
36.2		 2x2iA-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1050_2
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 TRP A 441
MET A 444
ARG A 526
TRP A 539
 3CU  A1001 (-4.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
 0.52A 2x2iA-3cttA:
36.1		 2x2iA-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_B_QPSB1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.60A 2x2iB-3cttA:
32.4		 2x2iB-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 2x2iC-3cttA:
36.2		 2x2iC-3cttA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 203
ASP A 327
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 2x2iD-3cttA:
32.3		 2x2iD-3cttA:
24.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
ASP A 443
MET A 444
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.49A 3l4wA-3cttA:
60.8		 3l4wA-3cttA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3L4W_A_MIGA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 441
ASP A 443
MET A 444
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.19A 3l4wA-3cttA:
60.8		 3l4wA-3cttA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.45A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
ARG A 526
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.44A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_A_ACRA701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.17A 3phaA-3cttA:
35.5		 3phaA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.48A 3phaB-3cttA:
40.9		 3phaB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 542
ASP A 366
ILE A 364
ILE A 328
ASP A 203
 3CU  A1001 ( 2.5A)
None
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
GOL  A3001 (-2.6A)
 1.18A 3phaB-3cttA:
40.9		 3phaB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
TRP A 406
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.43A 3phaC-3cttA:
40.8		 3phaC-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
ARG A 526
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.39A 3phaC-3cttA:
40.8		 3phaC-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 328
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.44A 3phaD-3cttA:
41.2		 3phaD-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ASP A 327
ILE A 364
MET A 444
ASP A 542
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.43A 3phaD-3cttA:
41.2		 3phaD-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.48A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.93A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_A_ACRA664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.45A 3pocA-3cttA:
40.9		 3pocA-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.49A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.97A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB664_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.47A 3pocB-3cttA:
42.1		 3pocB-3cttA:
24.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 PRO A 206
ASP A 327
ILE A 364
ASP A 443
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.29A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 TRP A 406
MET A 444
ARG A 526
ASP A 542
PHE A 575
 None
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.20A 3topA-3cttA:
48.7		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_A_ACRA1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 5 ILE A 328
TRP A 441
TRP A 539
THR A 544
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.6A)
None
 0.21A 3topA-3cttA:
48.6		 3topA-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TOP_B_ACRB1_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.51A 3topB-3cttA:
48.7		 3topB-3cttA:
43.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASN A 207
ASP A 327
ILE A 364
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3w37A-3cttA:
47.9		 3w37A-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3W37_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.33A 3w37A-3cttA:
47.9		 3w37A-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASN A 207
ASP A 327
ILE A 328
ASP A 542
PHE A 575
 None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.43A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		9 / 12 ASN A 207
ASP A 327
ILE A 364
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 None
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		9 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.33A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEL_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ILE A 328
TRP A 406
MET A 444
TRP A 539
 3CU  A1001 ( 3.9A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
 0.45A 3welA-3cttA:
48.1		 3welA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEM_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3wemA-3cttA:
47.4		 3wemA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEN_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
TRP A 441
ASP A 443
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.69A 3wenA-3cttA:
47.5		 3wenA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_1
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASN A 207
ASP A 327
ILE A 328
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 3weoA-3cttA:
55.0		 3weoA-3cttA:
36.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 6 ILE A 364
TRP A 406
MET A 444
TRP A 539
 3CU  A1001 (-4.5A)
None
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
 0.47A 3weoA-3cttA:
55.0		 3weoA-3cttA:
36.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 327
ILE A 328
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.34A 4b9zA-3cttA:
36.9		 4b9zA-3cttA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.37A 4b9zA-3cttA:
36.9		 4b9zA-3cttA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.31A 4feuA-3cttA:
0.5
4feuB-3cttA:
undetectable		 4feuA-3cttA:
15.32
4feuB-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.40A 4fevE-3cttA:
0.0		 4fevE-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 SER A 297
ASP A 203
ASP A 571
ASP A 542
HIS A 538
 None
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 2.5A)
None
 1.44A 4fewE-3cttA:
0.5
4fewF-3cttA:
0.5		 4fewE-3cttA:
15.32
4fewF-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_E_KANE301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 SER A 297
ASP A 443
ASP A 203
ASP A 571
HIS A 538
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.28A 4fewE-3cttA:
0.5
4fewF-3cttA:
0.5		 4fewE-3cttA:
15.32
4fewF-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.48A 4gkhC-3cttA:
1.7
4gkhD-3cttA:
0.0		 4gkhC-3cttA:
15.32
4gkhD-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_H_KANH301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 10 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.38A 4gkhG-3cttA:
0.0
4gkhH-3cttA:
1.5		 4gkhG-3cttA:
15.32
4gkhH-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_I_KANI301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 ASP A 443
ASP A 203
ASP A 571
GLU A 182
HIS A 538
 3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
None
 1.48A 4gkhI-3cttA:
0.0
4gkhJ-3cttA:
0.0		 4gkhI-3cttA:
15.32
4gkhJ-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 10 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.35A 4gkhK-3cttA:
0.2
4gkhL-3cttA:
1.5		 4gkhK-3cttA:
15.32
4gkhL-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 11 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.39A 4gkiC-3cttA:
0.0
4gkiD-3cttA:
1.5		 4gkiC-3cttA:
15.32
4gkiD-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_L_KANL301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 HIS A 538
ASP A 443
ASP A 203
ASP A 571
GLU A 182
 None
3CU  A1001 (-2.7A)
GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
None
 1.50A 4gkiK-3cttA:
1.7
4gkiL-3cttA:
1.7		 4gkiK-3cttA:
15.32
4gkiL-3cttA:
15.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_1
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
ASP A 443
MET A 444
PHE A 450
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
None
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.47A 5iefA-3cttA:
49.1		 5iefA-3cttA:
29.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEF_A_NBVA1005_2
(NEUTRAL
ALPHA-GLUCOSIDASE AB)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		4 / 4 ARG A 526
TRP A 539
ASP A 571
ARG A 598
 3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 4.7A)
 0.41A 5iefA-3cttA:
49.1		 5iefA-3cttA:
29.99
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN6_A_MIGA1013_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 364
TRP A 406
TRP A 441
ASP A 443
MET A 444
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.71A 5nn6A-3cttA:
51.5		 5nn6A-3cttA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ASP A 327
ILE A 364
TRP A 406
TRP A 441
ASP A 443
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 5nn8A-3cttA:
54.9		 5nn8A-3cttA:
44.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NN8_A_ACRA1015_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ASP A 571
ASP A 542
ASP A 443
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 4.8A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-2.7A)
3CU  A1001 (-3.9A)
 1.44A 5nn8A-3cttA:
54.9		 5nn8A-3cttA:
44.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1401_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 10 TRP A 441
ASP A 443
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-4.9A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.50A 5x7pA-3cttA:
32.8		 5x7pA-3cttA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.28A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.93A 6c9xA-3cttA:
35.7		 6c9xA-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 203
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.41A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.27A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9X_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.94A 6c9xB-3cttA:
35.7		 6c9xB-3cttA:
25.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 328
MET A 444
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.50A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.00A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.53A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_A_VOGA701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.03A 6c9zA-3cttA:
34.3		 6c9zA-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ILE A 328
MET A 444
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.44A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		5 / 12 ASP A 203
ILE A 364
MET A 444
ARG A 526
PHE A 575
 GOL  A3001 (-2.6A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.5A)
 1.10A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 ASP A 203
TYR A 299
ILE A 328
ILE A 364
TRP A 406
ASP A 443
MET A 444
ARG A 526
TRP A 539
PHE A 575
HIS A 600
 GOL  A3001 (-2.6A)
3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.52A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C9Z_B_VOGB701_0
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.02A 6c9zB-3cttA:
35.5		 6c9zB-3cttA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.77A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.41A 6ca1A-3cttA:
40.8		 6ca1A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.40A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.79A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA1_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.44A 6ca1B-3cttA:
39.4		 6ca1B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.47A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		11 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.47A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_A_MIGA701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 TYR A 299
ASP A 327
ILE A 328
ILE A 364
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-3.6A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.89A 6ca3A-3cttA:
35.7		 6ca3A-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		10 / 12 ASP A 327
ILE A 328
ILE A 364
ASP A 443
MET A 444
ARG A 526
TRP A 539
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 (-4.6A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.42A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		8 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
ASP A 443
ASP A 542
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-2.7A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 0.78A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		7 / 12 ASP A 327
ILE A 328
ILE A 364
TRP A 406
TRP A 441
PHE A 575
HIS A 600
 3CU  A1001 (-2.7A)
3CU  A1001 ( 3.9A)
3CU  A1001 (-4.5A)
None
3CU  A1001 (-4.9A)
3CU  A1001 (-4.5A)
3CU  A1001 (-3.9A)
 1.25A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CA3_B_MIGB701_1
(GLYCOSYL HYDROLASE,
FAMILY 31)		 3ctt MALTASE-GLUCOAMYLASE
(Homo
sapiens) 		6 / 12 ASP A 327
ILE A 364
MET A 444
ARG A 526
ASP A 542
PHE A 575
 3CU  A1001 (-2.7A)
3CU  A1001 (-4.5A)
3CU  A1001 ( 3.9A)
3CU  A1001 ( 3.5A)
3CU  A1001 ( 2.5A)
3CU  A1001 (-4.5A)
 1.47A 6ca3B-3cttA:
34.4		 6ca3B-3cttA:
6.67