SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3C0'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 (-4.4A)
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.52A 4dajA-4u16A:
35.6
4dajA-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 234
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.44A 4dajA-4u16A:
35.6
4dajA-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 TYR A 148
SER A 151
ASN A 152
TRP A 199
TYR A 529
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 (-4.4A)
3C0  A1202 (-3.7A)
1.36A 4dajA-4u16A:
35.6
4dajA-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ASP A 147
TYR A 148
SER A 151
TRP A 199
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-4.4A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.43A 4dajB-4u16A:
35.7
4dajB-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.33A 4dajB-4u16A:
35.7
4dajB-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_B_0HKB2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.40A 4dajB-4u16A:
35.7
4dajB-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
THR A 234
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 (-4.4A)
None
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.49A 4dajC-4u16A:
39.4
4dajC-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ASP A 147
TYR A 148
THR A 234
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.37A 4dajC-4u16A:
39.4
4dajC-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_C_0HKC2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 SER A 151
ASN A 152
TYR A 529
TYR A 533
CYH A 532
3C0  A1202 (-2.9A)
None
3C0  A1202 (-3.7A)
3C0  A1202 (-4.5A)
3C0  A1202 (-3.6A)
1.40A 4dajC-4u16A:
39.4
4dajC-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ASP A 147
TYR A 148
SER A 151
ASN A 152
TRP A 199
THR A 231
THR A 234
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 (-4.4A)
None
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.46A 4dajD-4u16A:
35.5
4dajD-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
8 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.40A 4dajD-4u16A:
35.5
4dajD-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DAJ_D_0HKD2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 TYR A 148
SER A 151
ASN A 152
TRP A 199
TRP A 503
TYR A 529
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 (-4.4A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
1.48A 4dajD-4u16A:
35.5
4dajD-4u16A:
86.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 234
ALA A 238
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.26A 4u14A-4u16A:
36.2
4u14A-4u16A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ILE A 116
ASP A 147
TYR A 148
SER A 151
TRP A 199
THR A 231
ALA A 235
ALA A 238
TRP A 503
ASN A 507
TYR A 529
CYH A 532
None
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-4.4A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.47A 4u14A-4u16A:
36.2
4u14A-4u16A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ILE A 116
ASP A 147
TYR A 148
THR A 234
ASN A 507
TYR A 529
CYH A 532
None
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.38A 4u14A-4u16A:
36.2
4u14A-4u16A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U14_A_0HKA2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
4 / 4 ASN A 152
LEU A 225
PHE A 239
TYR A 506
None
None
None
3C0  A1202 (-3.7A)
0.43A 4u14A-4u16A:
36.2
4u14A-4u16A:
89.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.56A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.34A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.34A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 234
ALA A 238
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.37A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 ASP A 147
TYR A 148
TRP A 199
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-4.4A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.40A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
3 / 3 ASN A 152
PHE A 239
TYR A 506
None
None
3C0  A1202 (-3.7A)
0.40A 4u15A-4u16A:
50.6
4u15A-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
12 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
THR A 234
ALA A 235
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.42A 4u15B-4u16A:
47.3
4u15B-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ASP A 147
TYR A 148
SER A 151
THR A 231
TRP A 503
ASN A 507
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.6A)
1.31A 4u15B-4u16A:
47.3
4u15B-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 ASP A 147
TYR A 148
THR A 234
ALA A 238
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.6A)
1.22A 4u15B-4u16A:
47.3
4u15B-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
7 / 12 ASP A 147
TYR A 148
THR A 234
TRP A 503
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.39A 4u15B-4u16A:
47.3
4u15B-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U15_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
4 / 4 ASN A 152
TRP A 199
LEU A 225
PHE A 239
None
3C0  A1202 (-4.4A)
None
None
0.53A 4u15B-4u16A:
47.3
4u15B-4u16A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
10 / 12 ASP A 147
TYR A 148
SER A 151
ALA A 235
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.5A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.58A 5cxvA-4u16A:
39.2
5cxvA-4u16A:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
10 / 12 ASP A 147
TYR A 148
SER A 151
TRP A 199
ALA A 235
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-4.4A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.66A 5cxvA-4u16A:
39.2
5cxvA-4u16A:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CXV_A_0HKA501_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 ASP A 147
TYR A 148
TRP A 199
ALA A 238
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-4.4A)
3C0  A1202 (-3.5A)
3C0  A1202 (-3.6A)
1.28A 5cxvA-4u16A:
39.2
5cxvA-4u16A:
67.80
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 ASP A 147
TYR A 148
ALA A 235
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.5A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.47A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 ASP A 147
TYR A 148
SER A 151
TRP A 199
THR A 231
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-4.4A)
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.73A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 ASP A 147
TYR A 148
THR A 231
ALA A 235
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-3.5A)
3C0  A1202 (-3.6A)
1.44A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 231
TRP A 503
ASN A 507
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.6A)
1.40A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
6 / 12 ASP A 147
TYR A 148
THR A 234
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
None
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
1.49A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 ASP A 147
TYR A 148
TRP A 199
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.4A)
3C0  A1202 (-3.7A)
3C0  A1202 (-4.4A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.59A 5dsgA-4u16A:
40.8
5dsgA-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
5 / 12 LEU A 144
TRP A 503
TYR A 529
TYR A 533
CYH A 532
None
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-4.5A)
3C0  A1202 (-3.6A)
1.46A 5dsgB-4u16A:
42.6
5dsgB-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 TYR A 148
SER A 151
TRP A 199
LEU A 225
THR A 231
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-4.4A)
None
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.68A 5dsgB-4u16A:
42.6
5dsgB-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
11 / 12 TYR A 148
TRP A 199
LEU A 225
THR A 231
THR A 234
ALA A 238
TRP A 503
TYR A 506
ASN A 507
TYR A 529
CYH A 532
3C0  A1202 (-3.7A)
3C0  A1202 (-4.4A)
None
None
None
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
3C0  A1202 (-3.7A)
3C0  A1202 (-2.9A)
3C0  A1202 (-3.7A)
3C0  A1202 (-3.6A)
0.54A 5dsgB-4u16A:
42.6
5dsgB-4u16A:
75.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Escherichia
virus
T4;
Rattus
norvegicus)
3 / 3 ASP A 147
ASN A 152
PHE A 239
3C0  A1202 (-3.4A)
None
None
0.66A 5dsgB-4u16A:
42.6
5dsgB-4u16A:
75.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)
4u16 MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3

(Rattus
norvegicus;
Escherichia
virus
T4)
5 / 12 TRP A 143
LEU A 144
SER A 151
ALA A 238
TRP A 503
None
None
3C0  A1202 (-2.9A)
3C0  A1202 (-3.5A)
3C0  A1202 ( 4.0A)
1.46A 6drxA-4u16A:
25.6
6drxA-4u16A:
29.23