SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3BZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 2qvx 4-CHLOROBENZOATE COA
LIGASE
(Alcaligenes
sp.
AL3007) 		4 / 5 VAL X 209
VAL X 208
THR X 251
ARG X 181
 3BZ  X 505 (-4.9A)
None
None
None
 1.10A 3bjwA-2qvxX:
undetectable		 3bjwA-2qvxX:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 2qvx 4-CHLOROBENZOATE COA
LIGASE
(Alcaligenes
sp.
AL3007) 		4 / 5 VAL X 209
VAL X 208
THR X 251
ARG X 181
 3BZ  X 505 (-4.9A)
None
None
None
 1.13A 3bjwC-2qvxX:
undetectable		 3bjwC-2qvxX:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 2qvx 4-CHLOROBENZOATE COA
LIGASE
(Alcaligenes
sp.
AL3007) 		5 / 10 GLY X 303
ALA X 280
PRO X 252
THR X 283
GLY X 321
 3BZ  X 505 ( 3.9A)
3BZ  X 505 (-3.5A)
None
None
None
 1.14A 6e5zA-2qvxX:
2.5		 6e5zA-2qvxX:
16.67