SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '36S'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I2Z_A_SALA1100_1
(SERUM ALBUMIN)		 4qpp PROTEIN ARGININE
N-METHYLTRANSFERASE
6
(Homo
sapiens) 		4 / 5 LEU A 353
LEU A 191
ILE A 290
ILE A 341
 36S  A1001 ( 4.5A)
None
None
None
 0.57A 2i2zA-4qppA:
undetectable		 2i2zA-4qppA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4qpp PROTEIN ARGININE
N-METHYLTRANSFERASE
6
(Homo
sapiens) 		5 / 12 GLY A 270
GLY A 272
LEU A 356
GLU A 266
ALA A 269
 36S  A1001 ( 4.7A)
None
None
None
None
 1.17A 3sxjA-4qppA:
8.9		 3sxjA-4qppA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4qpp PROTEIN ARGININE
N-METHYLTRANSFERASE
6
(Homo
sapiens) 		5 / 12 GLY A 270
GLY A 272
LEU A 356
GLU A 266
ALA A 269
 36S  A1001 ( 4.7A)
None
None
None
None
 1.17A 3sxjB-4qppA:
9.2		 3sxjB-4qppA:
20.74