SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '33L'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1STF_E_CCSE25_0 (PAPAIN STEFIN B (CYSTATIN B))	4qh6	CRUZIPAIN (Trypanosoma cruzi)	7 / 10	GLN A 19 GLY A 23 SER A 24 TRP A 26 PHE A 28 SER A 29 HIS A 162	33L A 301 (-3.7A) 33L A 301 (-3.7A) None None None None 33L A 301 (-4.7A)	0.31A	1stfE-4qh6A: 32.2 1stfI-4qh6A: 1.7	1stfE-4qh6A: 38.29 1stfI-4qh6A: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AI8_A_HNQA255_1 (CATHEPSIN B)	4qh6	CRUZIPAIN (Trypanosoma cruzi)	4 / 7	GLN A 19 GLY A 23 HIS A 162 TRP A 184	33L A 301 (-3.7A) 33L A 301 (-3.7A) 33L A 301 (-4.7A) None	0.28A	3ai8A-4qh6A: 27.2	3ai8A-4qh6A: 28.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC1_A_486A801_2 (GLUCOCORTICOID RECEPTOR)	4qh6	CRUZIPAIN (Trypanosoma cruzi)	3 / 3	TRP A 26 MET A 68 ASN A 69	None 33L A 301 (-3.6A) None	1.23A	5uc1B-4qh6A: undetectable	5uc1B-4qh6A: 19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC1_B_486B801_1 (GLUCOCORTICOID RECEPTOR)	4qh6	CRUZIPAIN (Trypanosoma cruzi)	3 / 3	TRP A 26 MET A 68 ASN A 69	None 33L A 301 (-3.6A) None	1.24A	5uc1A-4qh6A: undetectable	5uc1A-4qh6A: 19.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1STF_E_CCSE25_0","PAPAIN;STEFIN B (CYSTATIN B)","4qh6","CRUZIPAIN","Trypanosoma cruzi",7,"GLN A  19;GLY A  23;SER A  24;TRP A  26;PHE A  28;SER A  29;HIS A 162","33L A 301 (-3.7A);33L A 301 (-3.7A);None;None;None;None;33L A 301 (-4.7A)","0.31A","1stfE-4qh6A:32.2;1stfI-4qh6A:1.7",null],["3AI8_A_HNQA255_1","CATHEPSIN B","4qh6","CRUZIPAIN","Trypanosoma cruzi",4,"GLN A  19;GLY A  23;HIS A 162;TRP A 184","33L A 301 (-3.7A);33L A 301 (-3.7A);33L A 301 (-4.7A);None","0.28A","3ai8A-4qh6A:27.2","1stfE-4qh6A:38.29;1stfI-4qh6A:14.75"],["5UC1_A_486A801_2","GLUCOCORTICOID RECEPTOR;GLUCOCORTICOID RECEPTOR","4qh6","CRUZIPAIN","Trypanosoma cruzi",3,"TRP A  26;MET A  68;ASN A  69","None;33L A 301 (-3.6A);None","1.23A","5uc1B-4qh6A:undetectable","3ai8A-4qh6A:28.91"],["5UC1_B_486B801_1","GLUCOCORTICOID RECEPTOR;GLUCOCORTICOID RECEPTOR","4qh6","CRUZIPAIN","Trypanosoma cruzi",3,"TRP A  26;MET A  68;ASN A  69","None;33L A 301 (-3.6A);None","1.24A","5uc1A-4qh6A:undetectable","5uc1B-4qh6A:19.02"]]