SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '30N'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEY_B_EV1B1771_1 (CAMP AND CAMP-INHIBITED CGMP 3', 5'-CYCLIC PHOSPHODIESTERASE)	4qc6	BIFUNCTIONAL AAC/APH (Staphylococcus warneri)	5 / 8	LEU A 124 ILE A 117 TYR A 148 PHE A 153 GLN A 100	None None 30N A 202 (-4.5A) None None	1.28A	2weyB-4qc6A: undetectable	2weyB-4qc6A: 17.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3S79_A_ASDA601_1 (CYTOCHROME P450 19A1)	4qc6	BIFUNCTIONAL AAC/APH (Staphylococcus warneri)	5 / 12	ILE A 70 ILE A 112 VAL A 30 LEU A 25 MET A 21	None 30N A 202 (-4.9A) None FMT A 203 ( 4.4A) None	0.98A	3s79A-4qc6A: undetectable	3s79A-4qc6A: 17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JKV_A_ASDA602_1 (AROMATASE)	4qc6	BIFUNCTIONAL AAC/APH (Staphylococcus warneri)	5 / 12	ILE A 70 ILE A 112 VAL A 30 LEU A 25 MET A 21	None 30N A 202 (-4.9A) None FMT A 203 ( 4.4A) None	0.96A	5jkvA-4qc6A: undetectable	5jkvA-4qc6A: 17.03