SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2UO'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HKK_A_ALEA300_1 (CARBONIC ANHYDRASE 2)	4oqr	CYP105AS1 (Amycolatopsis orientalis)	4 / 6	ASN A 67 ASN A 96 ILE A 236 THR A 286	HEM A 501 ( 4.8A) None 2UO A 502 (-4.1A) 2UO A 502 ( 4.4A)	1.08A	2hkkA-4oqrA: undetectable	2hkkA-4oqrA: 20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FWI_A_CAMA420_0 (CAMPHOR 5-MONOOXYGENASE)	4oqr	CYP105AS1 (Amycolatopsis orientalis)	4 / 7	THR A 95 VAL A 239 THR A 244 VAL A 282	2UO A 502 (-4.0A) 2UO A 502 ( 4.9A) HEM A 501 (-3.1A) 2UO A 502 ( 4.4A)	0.84A	3fwiA-4oqrA: 41.8	3fwiA-4oqrA: 28.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NM5_B_LOCB502_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	4oqr	CYP105AS1 (Amycolatopsis orientalis)	4 / 4	ASN A 247 SER A 181 ALA A 389 VAL A 282	None None 2UO A 502 ( 4.1A) 2UO A 502 ( 4.4A)	0.96A	5nm5A-4oqrA: undetectable	5nm5A-4oqrA: 24.39