SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2RH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 3o3o ALPHA-SUBUNIT
2-HYDROXYISOCAPROYL-
COA DEHYDRATASE
(Clostridioides
difficile) 		6 / 12 VAL A  38
LEU A 214
ALA A 293
MET A 313
ASN A 315
GLY A 264
 None
None
None
None
2RH  A 410 (-3.5A)
None
 1.43A 4qckA-3o3oA:
undetectable		 4qckA-3o3oA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDC_A_ASDA404_1
(3-KETOSTEROID
9ALPHA-HYDROXYLASE
OXYGENASE)		 3o3o ALPHA-SUBUNIT
2-HYDROXYISOCAPROYL-
COA DEHYDRATASE
(Clostridioides
difficile) 		5 / 12 VAL A  38
MET A 218
ALA A 293
MET A 313
ASN A 315
 None
2RH  A 410 ( 4.9A)
None
None
2RH  A 410 (-3.5A)
 1.45A 4qdcA-3o3oA:
undetectable		 4qdcA-3o3oA:
21.84