SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2OH'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1GTN_V_TRPV81_0 (TRP RNA-BINDINGATTENUATION PROTEIN) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 12 | GLY A 83ALA A 181GLY A 232ALA A 180ILE A 236 | None2OH A 402 (-3.9A)2OH A 402 ( 3.8A)2OH A 402 ( 3.8A)None | 0.90A | 1gtnL-5it1A:undetectable1gtnV-5it1A:undetectable | 1gtnL-5it1A:9.041gtnV-5it1A:9.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UTD_L_TRPL81_0 (TRANSCRIPTIONATTENUATION PROTEINMTRB) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 12 | GLY A 232ALA A 180ILE A 236GLY A 83ALA A 181 | 2OH A 402 ( 3.8A)2OH A 402 ( 3.8A)NoneNone2OH A 402 (-3.9A) | 0.86A | 1utdL-5it1A:undetectable1utdM-5it1A:undetectable | 1utdL-5it1A:9.041utdM-5it1A:9.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UTD_O_TRPO81_0 (TRANSCRIPTIONATTENUATION PROTEINMTRB) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 12 | GLY A 232ALA A 180ILE A 236GLY A 83ALA A 181 | 2OH A 402 ( 3.8A)2OH A 402 ( 3.8A)NoneNone2OH A 402 (-3.9A) | 0.85A | 1utdO-5it1A:undetectable1utdP-5it1A:undetectable | 1utdO-5it1A:9.041utdP-5it1A:9.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1UTD_P_TRPP81_0 (TRANSCRIPTIONATTENUATION PROTEINMTRB) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 11 | GLY A 232ALA A 180ILE A 236GLY A 83ALA A 181 | 2OH A 402 ( 3.8A)2OH A 402 ( 3.8A)NoneNone2OH A 402 (-3.9A) | 0.84A | 1utdP-5it1A:undetectable1utdQ-5it1A:undetectable | 1utdP-5it1A:9.041utdQ-5it1A:9.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2VCT_C_ASDC1223_1 (GLUTATHIONES-TRANSFERASE A2) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 4 / 8 | ILE A 236GLY A 232LEU A 193LEU A 192 | None2OH A 402 ( 3.8A)NoneNone | 0.93A | 2vctC-5it1A:undetectable | 2vctC-5it1A:20.20 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4J7X_B_SASB804_1 (SEPIAPTERINREDUCTASE) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 12 | LEU A 234PHE A 155ALA A 169GLY A 190LEU A 189 | HEM A 401 ( 4.4A)NoneNone2OH A 402 ( 4.6A)2OH A 402 ( 4.3A) | 1.00A | 4j7xB-5it1A:undetectable | 4j7xB-5it1A:21.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BRD_B_RFPB502_1 (RIFAMPINMONOOXYGENASE) |
5it1 | PUTATIVE CYTOCHROMEP450 (Streptomycespeucetius) | 5 / 12 | GLY A 156ARG A 161VAL A 157GLY A 190GLY A 191 | NoneNoneNone2OH A 402 ( 4.6A)None | 1.12A | 6brdB-5it1A:undetectable | 6brdB-5it1A:13.42 |