SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2LY'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5cqa BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B
(Homo
sapiens) 		4 / 4 VAL A1893
VAL A1898
ASN A1944
ILE A1950
 2LY  A2001 ( 4.8A)
2LY  A2001 ( 4.9A)
2LY  A2001 (-3.2A)
2LY  A2001 ( 4.5A)
 0.10A 4cutA-5cqaA:
22.2		 4cutA-5cqaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5cqa BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B
(Homo
sapiens) 		6 / 6 PRO A1888
VAL A1893
VAL A1898
TYR A1901
ASN A1944
ILE A1950
 2LY  A2001 (-4.9A)
2LY  A2001 ( 4.8A)
2LY  A2001 ( 4.9A)
None
2LY  A2001 (-3.2A)
2LY  A2001 ( 4.5A)
 0.11A 5pbeA-5cqaA:
22.3		 5pbeA-5cqaA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5cqa BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B
(Homo
sapiens) 		4 / 8 VAL A1893
CYH A1940
ASN A1944
ILE A1950
 2LY  A2001 ( 4.8A)
2LY  A2001 ( 4.3A)
2LY  A2001 (-3.2A)
2LY  A2001 ( 4.5A)
 0.55A 5y1yA-5cqaA:
15.7		 5y1yA-5cqaA:
31.45